Insights into the molecular recognition of the 5'-GNN-3' family of DNA sequences by zinc finger domains.
about
Zinc finger nucleases: custom-designed molecular scissors for genome engineering of plant and mammalian cellsTherapeutic modulation of endogenous gene function by agents with designed DNA-sequence specificitiesA rapid, generally applicable method to engineer zinc fingers illustrated by targeting the HIV-1 promoterTargeted genome editing in human cells with zinc finger nucleases constructed via modular assemblyZinc Finger Tools: custom DNA-binding domains for transcription factors and nucleasesOrigins of Programmable Nucleases for Genome EngineeringDevelopment of zinc finger domains for recognition of the 5'-ANN-3' family of DNA sequences and their use in the construction of artificial transcription factorsEngineering polydactyl zinc-finger transcription factorsDevelopment of zinc finger domains for recognition of the 5'-CNN-3' family DNA sequences and their use in the construction of artificial transcription factorsDirected evolution of an enhanced and highly efficient FokI cleavage domain for zinc finger nucleasesUtrophin up-regulation by an artificial transcription factor in transgenic miceZinc-finger-based transcriptional repression of rhodopsin in a model of dominant retinitis pigmentosa.Electrospray ionization mass spectrometry of oligonucleotide complexes with drugs, metals, and proteins.Scanning the human genome with combinatorial transcription factor libraries.Genetic reprogramming of tumor cells by zinc finger transcription factorsLaboratory-directed protein evolutionDesign of a zinc finger protein binding a sequence upstream of the A20 gene.ZFN-site searches genomes for zinc finger nuclease target sites and off-target sites.Custom-designed zinc finger nucleases: what is next?Synthetic zinc finger proteins: the advent of targeted gene regulation and genome modification technologies.Heritable endogenous gene regulation in plants with designed polydactyl zinc finger transcription factors.Zinc finger nucleases for targeted mutagenesis and repair of the sickle-cell disease mutation: An in-silico study.Attenuation of HIV-1 replication in primary human cells with a designed zinc finger transcription factor.Chimeric TALE recombinases with programmable DNA sequence specificityInhibition of human immunodeficiency virus type 1 replication with artificial transcription factors targeting the highly conserved primer-binding site.Global analysis of Drosophila Cys₂-His₂ zinc finger proteins reveals a multitude of novel recognition motifs and binding determinants.Targeted chromosomal cleavage and mutagenesis in Drosophila using zinc-finger nucleasesA zinc finger protein array for the visual detection of specific DNA sequences for diagnostic applicationsIdentity of zinc finger nucleases with specificity to herpes simplex virus type II genomic DNA: novel HSV-2 vaccine/therapy precursorsProviral HIV-genome-wide and pol-gene specific zinc finger nucleases: usability for targeted HIV gene therapy.Determining the specificities of TALENs, Cas9, and other genome-editing enzymesA systematic survey of the Cys2His2 zinc finger DNA-binding landscape.Fusion proteins consisting of human immunodeficiency virus type 1 integrase and the designed polydactyl zinc finger protein E2C direct integration of viral DNA into specific sitesEpigenetic reprogramming of cancer cells via targeted DNA methylation.Zinc finger arrays binding human papillomavirus types 16 and 18 genomic DNA: precursors of gene-therapeutics for in-situ reversal of associated cervical neoplasiaPredicting DNA recognition by Cys2His2 zinc finger proteins.Synthesis of programmable integrases.Zinc Finger Database (ZiFDB): a repository for information on C2H2 zinc fingers and engineered zinc-finger arrays.Comparing zinc finger nucleases and transcription activator-like effector nucleases for gene targeting in Drosophila.Site-specific integration of retroviral DNA in human cells using fusion proteins consisting of human immunodeficiency virus type 1 integrase and the designed polydactyl zinc-finger protein E2C.
P2860
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P2860
Insights into the molecular recognition of the 5'-GNN-3' family of DNA sequences by zinc finger domains.
description
2000 nî lūn-bûn
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2000 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2000 թվականի նոյեմբերին հրատարակված գիտական հոդված
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2000年の論文
@ja
2000年論文
@yue
2000年論文
@zh-hant
2000年論文
@zh-hk
2000年論文
@zh-mo
2000年論文
@zh-tw
2000年论文
@wuu
name
Insights into the molecular re ...... uences by zinc finger domains.
@ast
Insights into the molecular re ...... uences by zinc finger domains.
@en
type
label
Insights into the molecular re ...... uences by zinc finger domains.
@ast
Insights into the molecular re ...... uences by zinc finger domains.
@en
prefLabel
Insights into the molecular re ...... uences by zinc finger domains.
@ast
Insights into the molecular re ...... uences by zinc finger domains.
@en
P2093
P356
P1476
Insights into the molecular re ...... uences by zinc finger domains.
@en
P2093
P304
P356
10.1006/JMBI.2000.4133
P407
P577
2000-11-01T00:00:00Z