Tar DNA binding protein-43 (TDP-43) associates with stress granules: analysis of cultured cells and pathological brain tissue
about
Redox signalling directly regulates TDP-43 via cysteine oxidation and disulphide cross-linkingTDP-35 sequesters TDP-43 into cytoplasmic inclusions through binding with RNATARDBP mutation analysis in TDP-43 proteinopathies and deciphering the toxicity of mutant TDP-43Altered ribostasis: RNA-protein granules in degenerative disordersRecent progress in the discovery of small molecules for the treatment of amyotrophic lateral sclerosis (ALS)Conjoint pathologic cascades mediated by ALS/FTLD-U linked RNA-binding proteins TDP-43 and FUSInside out: the role of nucleocytoplasmic transport in ALS and FTLDRedox Imbalance and Viral Infections in Neurodegenerative DiseasesAlterations in stress granule dynamics driven by TDP-43 and FUS: a link to pathological inclusions in ALS?TDP-43: a new player on the AD field?Pathological mechanisms underlying TDP-43 driven neurodegeneration in FTLD-ALS spectrum disordersConverging mechanisms in ALS and FTD: disrupted RNA and protein homeostasisRole of stress granules and RNA-binding proteins in neurodegeneration: a mini-reviewTherapeutic and diagnostic challenges for frontotemporal dementiaDoes a loss of TDP-43 function cause neurodegeneration?ALS-associated TDP-43 induces endoplasmic reticulum stress, which drives cytoplasmic TDP-43 accumulation and stress granule formationStress Granules Modulate SYK to Cause Microglial Cell Dysfunction in Alzheimer's Disease.RNA-processing protein TDP-43 regulates FOXO-dependent protein quality control in stress responseFUS and TARDBP but not SOD1 interact in genetic models of amyotrophic lateral sclerosisPub1p C-Terminal RRM Domain Interacts with Tif4631p through a Conserved Region Neighbouring the Pab1p Binding SiteStructural and molecular insights into the mechanism of action of human angiogenin-ALS variants in neuronsTDP-43 aggregation in neurodegeneration: are stress granules the key?TDP-43 Proteinopathy and ALS: Insights into Disease Mechanisms and Therapeutic Targets.Frontotemporal dementia: a bridge between dementia and neuromuscular diseaseLegal but lethal: functional protein aggregation at the verge of toxicityThe LO-BaFL method and ALS microarray expression analysisWelander distal myopathy is caused by a mutation in the RNA-binding protein TIA1Oxr1 improves pathogenic cellular features of ALS-associated FUS and TDP-43 mutationsFUS Interacts with HSP60 to Promote Mitochondrial DamageAberrant localization of FUS and TDP43 is associated with misfolding of SOD1 in amyotrophic lateral sclerosisAre aberrant phase transitions a driver of cellular aging?The Myoblast C2C12 Transfected with Mutant Valosin-Containing Protein Exhibits Delayed Stress Granule Resolution on Oxidative Stress.The ALS disease protein TDP-43 is actively transported in motor neuron axons and regulates axon outgrowth.Overexpression of ALS-associated p.M337V human TDP-43 in mice worsens disease features compared to wild-type human TDP-43 mice.A high-content screen identifies novel compounds that inhibit stress-induced TDP-43 cellular aggregation and associated cytotoxicity.Inhibition of TDP-43 accumulation by bis(thiosemicarbazonato)-copper complexes.Gene expression responses to FUS, EWS, and TAF15 reduction and stress granule sequestration analyses identifies FET-protein non-redundant functions.Kinase Inhibitor Screening Identifies Cyclin-Dependent Kinases and Glycogen Synthase Kinase 3 as Potential Modulators of TDP-43 Cytosolic Accumulation during Cell Stress.Prions, amyloids, and RNA: Pieces of a puzzle.Mitochondrial dysfunction and decrease in body weight of a transgenic knock-in mouse model for TDP-43.
P2860
Q24300438-359E8062-BC60-4C2D-8765-82BA60224B48Q24338199-82943B95-9069-4651-BCEC-F3FAD4409E4CQ24594172-0B80DEEB-E0DC-4C2B-B316-709BC5E77FF1Q24604643-3ECDCA58-4CB4-4BD9-98DC-DD6C0AC74DB6Q24613709-D01B69C5-A154-467A-B4AB-5E0A3E9E5D19Q24634807-7A953EE4-E02F-465B-9295-2FA1CF184793Q26748482-B5F1C7F3-DDCE-4427-803A-5AF828C5CA15Q26750630-B6C15F68-1D81-4BA2-900E-D8C69583623FQ26777971-A78E8318-887D-4E68-8A3D-B2B02DD5C406Q26823723-8D5C49E1-EAA6-4D70-9EF1-FF1969F904A1Q26828357-58B6600C-5078-451E-A46E-F896BE9B6492Q26863439-BB54A9B9-0EAE-4DF7-BC51-C0BF64607090Q26864147-05A399BA-A3A5-4A5F-98EE-E158F983A53FQ26998919-3BBDB058-F5CD-44F4-9619-3163B905697FQ27026848-2311EE5F-2849-41C1-BBFB-7FF4F1C3AD58Q27301374-8FF1FEA5-FD22-463E-BAE9-804014CEE752Q27311810-E1D88636-D35D-472C-8112-3684C838C30DQ27312567-50CCDEA9-DF60-4DD6-8AAD-1D2949149EABQ27339258-8B857E48-5B7E-48B2-BFDA-3881EE32D1C4Q27674307-176A6E2C-3C19-4F3F-B499-8FE6E54A3714Q27674359-15FDA2EE-9052-4689-BF31-F70C3839666CQ27692111-4A3069A7-1AF9-4C43-8A19-C96ED5290296Q28080628-B3C44AF1-03CD-4E7F-9F09-3F1D128E6F72Q28081198-FA6A71B1-C5FA-4845-B782-DF25F1A06387Q28084859-C10BDF5F-3974-4D11-AD78-C5E46D0867BEQ28275676-73CF3A75-5610-43E9-9C3A-16AF822EC919Q28285385-627614C1-8864-4F2B-925F-D00B85CD77E7Q28383058-3B5030D2-2051-440A-B003-1C10AC7738A0Q28547727-9AA89291-66AA-4B6C-BF58-2FDD7440D335Q28730723-2AE63B28-0C11-41A1-A357-F0A545629616Q28821465-D232D402-342D-49E6-8F9E-2CDDEA3F9250Q30008982-BEB5D6E1-345A-4B66-85E2-8CD145F48614Q30523244-A2EB7620-2693-4D28-8733-42F4E646FA31Q30541711-BE03A618-45C0-4FF1-B861-8608F2373257Q30570770-08AACE15-32F8-4EA0-A085-5B5A1C16B427Q31082029-EB61A9D6-E5B8-4211-9A35-D821A8E3EFA0Q31104690-2882BA7F-7D77-4244-A264-05CA6085F7A2Q31122876-386A00C5-A541-4F68-9C53-CB36001E2BC1Q33363261-5B4EA191-1F9C-4785-A274-C2A351A5DCB9Q33675871-5F21FF4A-1A54-4D28-97C5-0D0E52577B85
P2860
Tar DNA binding protein-43 (TDP-43) associates with stress granules: analysis of cultured cells and pathological brain tissue
description
2010 nî lūn-bûn
@nan
2010 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Tar DNA binding protein-43 (TD ...... and pathological brain tissue
@ast
Tar DNA binding protein-43 (TD ...... and pathological brain tissue
@en
Tar DNA binding protein-43 (TD ...... and pathological brain tissue
@nl
type
label
Tar DNA binding protein-43 (TD ...... and pathological brain tissue
@ast
Tar DNA binding protein-43 (TD ...... and pathological brain tissue
@en
Tar DNA binding protein-43 (TD ...... and pathological brain tissue
@nl
prefLabel
Tar DNA binding protein-43 (TD ...... and pathological brain tissue
@ast
Tar DNA binding protein-43 (TD ...... and pathological brain tissue
@en
Tar DNA binding protein-43 (TD ...... and pathological brain tissue
@nl
P2093
P2860
P3181
P1433
P1476
Tar DNA binding protein-43 (TD ...... and pathological brain tissue
@en
P2093
Allison Citro
Aylin Bilgutay
Benjamin Wolozin
Liqun Liu-Yesucevitz
Michael Sherman
Nava Zaarur
Robert Bowser
Tapan Mehta
Tara Vanderweyde
P2860
P304
P3181
P356
10.1371/JOURNAL.PONE.0013250
P407
P577
2010-10-11T00:00:00Z