Genomewide analyses define different modes of transcriptional regulation by peroxisome proliferator-activated receptor-β/δ (PPARβ/δ) - Wikidata - wikimedia - TriplyDB

Genomewide analyses define different modes of transcriptional regulation by peroxisome proliferator-activated receptor-β/δ (PPARβ/δ)

Genomewide analyses define different modes of transcriptional regulation by peroxisome proliferator-activated receptor-β/δ (PPARβ/δ)

http://www.wikidata.org/entity/Q28476779

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The role of peroxisome proliferator-activated receptors in carcinogenesis and chemoprevention Inverse PPARβ/δ agonists suppress oncogenic signaling to the ANGPTL4 gene and inhibit cancer cell invasion PPARδ regulates satellite cell proliferation and skeletal muscle regeneration PPARβ/δ promotes HRAS-induced senescence and tumor suppression by potentiating p-ERK and repressing p-AKT signaling Coex-Rank: An approach incorporating co-expression information for combined analysis of microarray data.Neuron-specific deletion of peroxisome proliferator-activated receptor delta (PPARδ) in mice leads to increased susceptibility to diet-induced obesity.Genome-wide binding patterns of thyroid hormone receptor beta.Analysis of the peroxisome proliferator-activated receptor-β/δ (PPARβ/δ) cistrome reveals novel co-regulatory role of ATF4.Mixed-polarization phenotype of ascites-associated macrophages in human ovarian carcinoma: correlation of CD163 expression, cytokine levels and early relapse.Regulation of TAK1/TAB1-mediated IL-1β signaling by cytoplasmic PPARβ/δ.Integrative and systemic approaches for evaluating PPARβ/δ (PPARD) function.PPARγ and NF-κB regulate the gene promoter activity of their shared repressor, TNIP1 An Ideal PPAR Response Element Bound to and Activated by PPARα.Conditional Expression of Human PPARδ and a Dominant Negative Variant of hPPARδ In Vivo Activation of PPAR-δ induces microRNA-100 and decreases the uptake of very low-density lipoprotein in endothelial cells.Deregulation of PPARβ/δ target genes in tumor-associated macrophages by fatty acid ligands in the ovarian cancer microenvironment.Research resource: The estrogen receptor α cistrome defined by DamIP Identification of a binding motif specific to HNF4 by comparative analysis of multiple nuclear receptors.Establishing the Role of PPARβ/δ in Carcinogenesis The coactivator PGC-1α regulates skeletal muscle oxidative metabolism independently of the nuclear receptor PPARβ/δ in sedentary mice fed a regular chow diet.PPARγ regulates resistance vessel tone through a mechanism involving RGS5-mediated control of protein kinase C and BKCa channel activity.Nuclear receptor/microRNA circuitry links muscle fiber type to energy metabolism.Peroxisome proliferator-activated receptor-β/δ regulates angiogenic cell behaviors and oxygen-induced retinopathy.PPARδ induces estrogen receptor-positive mammary neoplasia through an inflammatory and metabolic phenotype linked to mTOR activation.PPARβ/δ modulates ethanol-induced hepatic effects by decreasing pyridoxal kinase activity.PPARδ as a Metabolic Initiator of Mammary Neoplasia and Immune Tolerance The transcriptional PPARβ/δ network in human macrophages defines a unique agonist-induced activation state.Suppression of PPARβ, and DHA treatment, inhibit NaV1.5 and NHE-1 pro-invasive activities.Transcription factor binding site enrichment analysis predicts drivers of altered gene expression in nonalcoholic steatohepatitis.Molecular Pathways: Dietary Regulation of Stemness and Tumor Initiation by the PPAR-δ Pathway.Metabolic Reprogramming via PPARα Signaling in Cardiac Hypertrophy and Failure From Metabolomics to Epigenetics.Altered glycogen metabolism causes hepatomegaly following an Atg7 deletion.Cross-enhancement of ANGPTL4 transcription by HIF1 alpha and PPAR beta/delta is the result of the conformational proximity of two response elements PPARs as determinants of the estrogen receptor lineage: use of synthetic lethality for the treatment of estrogen receptor-negative breast cancer.PPARα Is Required for PPARδ Action in Regulation of Body Weight and Hepatic Steatosis in Mice.Plac1 Is a Key Regulator of the Inflammatory Response and Immune Tolerance In Mammary Tumorigenesis.

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Genomewide analyses define different modes of transcriptional regulation by peroxisome proliferator-activated receptor-β/δ (PPARβ/δ)

http://www.wikidata.org/entity/Q28476779

description

2011 nî lūn-bûn

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2011 թուականի Յունուարին հրատարակուած գիտական յօդուած

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2011年の論文

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Genomewide analyses define dif ...... tivated receptor-β/δ (PPARβ/δ)

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Anne Schönbauer

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Florian Finkernagel

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Helmut Blöcker

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Kerstin Kaddatz

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Maren Scharfe

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Michael Jarek

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Sabine Müller-Brüsselbach

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Wolfgang Meissner

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Identification and analysis of functional elements in 1% of the human genome by the ENCODE pilot project

Ultrafast and memory-efficient alignment of short DNA sequences to the human genome

Model-based analysis of ChIP-Seq (MACS)

Bioconductor: open software development for computational biology and bioinformatics

The peroxisome proliferator-activated receptor delta, an integrator of transcriptional repression and nuclear receptor signaling.

PANTHER version 7: improved phylogenetic trees, orthologs and collaboration with the Gene Ontology Consortium

SMRT repression of nuclear receptors controls the adipogenic set point and metabolic homeostasis

Structure of the intact PPAR-gamma-RXR- nuclear receptor complex on DNA

Fitting a mixture model by expectation maximization to discover motifs in biopolymers

Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources

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