Acyl-CoA carboxylases (accD2 and accD3), together with a unique polyketide synthase (Cg-pks), are key to mycolic acid biosynthesis in Corynebacterianeae such as Corynebacterium glutamicum and Mycobacterium tuberculosis
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Platensimycin activity against mycobacterial beta-ketoacyl-ACP synthasesComparative and functional genomics of Rhodococcus opacus PD630 for biofuels developmentComplete genome sequence and analysis of the multiresistant nosocomial pathogen Corynebacterium jeikeium K411, a lipid-requiring bacterium of the human skin floraBiosynthesis and function of polyacetylenes and allied natural productsBiosynthesis of mycobacterial arabinogalactan: identification of a novel alpha(1-->3) arabinofuranosyltransferaseStructural diversity in the six-fold redundant set of acyl-CoA carboxyltransferases in Mycobacterium tuberculosisThe reductase that catalyzes mycolic motif synthesis is required for efficient attachment of mycolic acids to arabinogalactanPathway to synthesis and processing of mycolic acids in Mycobacterium tuberculosisAccD6, a member of the Fas II locus, is a functional carboxyltransferase subunit of the acyl-coenzyme A carboxylase in Mycobacterium tuberculosisIdentification of an alpha(1-->6) mannopyranosyltransferase (MptA), involved in Corynebacterium glutamicum lipomanann biosynthesis, and identification of its orthologue in Mycobacterium tuberculosisACCase 6 is the essential acetyl-CoA carboxylase involved in fatty acid and mycolic acid biosynthesis in mycobacteriaIdentification of a novel arabinofuranosyltransferase (AftA) involved in cell wall arabinan biosynthesis in Mycobacterium tuberculosisIdentification and characterization of Rv3281 as a novel subunit of a biotin-dependent acyl-CoA Carboxylase in Mycobacterium tuberculosis H37RvBiochemical and structural characterization of an essential acyl coenzyme A carboxylase from Mycobacterium tuberculosisBiochemical characterization of the Mycobacterium tuberculosis phosphoribosyl-1-pyrophosphate synthetaseAnalysis of a new mannosyltransferase required for the synthesis of phosphatidylinositol mannosides and lipoarbinomannan reveals two lipomannan pools in corynebacterineaeIdentification of a Desaturase Involved in Mycolic Acid Biosynthesis in Mycobacterium smegmatisIdentification of KasA as the cellular target of an anti-tubercular scaffoldCharacterization of the Corynebacterium glutamicum deltapimB' deltamgtA double deletion mutant and the role of Mycobacterium tuberculosis orthologues Rv2188c and Rv0557 in glycolipid biosynthesisDirect visualization of the outer membrane of mycobacteria and corynebacteria in their native state.Synthesis and biological evaluation of NAS-21 and NAS-91 analogues as potential inhibitors of the mycobacterial FAS-II dehydratase enzyme Rv0636.Deletion of Cg-emb in corynebacterianeae leads to a novel truncated cell wall arabinogalactan, whereas inactivation of Cg-ubiA results in an arabinan-deficient mutant with a cell wall galactan core.The two carboxylases of Corynebacterium glutamicum essential for fatty acid and mycolic acid synthesisStructural characterization of a partially arabinosylated lipoarabinomannan variant isolated from a Corynebacterium glutamicum ubiA mutant.Genome sequence of Brucella abortus vaccine strain S19 compared to virulent strains yields candidate virulence genesLoss of a mycobacterial gene encoding a reductase leads to an altered cell wall containing beta-oxo-mycolic acid analogs and accumulation of ketones.The complete genome sequence of Corynebacterium pseudotuberculosis FRC41 isolated from a 12-year-old girl with necrotizing lymphadenitis reveals insights into gene-regulatory networks contributing to virulenceComplete genome sequence of Corynebacterium variabile DSM 44702 isolated from the surface of smear-ripened cheeses and insights into cheese ripening and flavor generationStructure-based inhibitor design of AccD5, an essential acyl-CoA carboxylase carboxyltransferase domain of Mycobacterium tuberculosisAssay development for identifying inhibitors of the mycobacterial FadD32 activity.Topology and mutational analysis of the single Emb arabinofuranosyltransferase of Corynebacterium glutamicum as a model of Emb proteins of Mycobacterium tuberculosis.Lipoarabinomannan biosynthesis in Corynebacterineae: the interplay of two α(1→2)-mannopyranosyltransferases MptC and MptD in mannan branching.Characterization of the mycobacterial acyl-CoA carboxylase holo complexes reveals their functional expansion into amino acid catabolismCharacterization of myo-inositol utilization by Corynebacterium glutamicum: the stimulon, identification of transporters, and influence on L-lysine formationHigh quality draft genome sequence of Corynebacterium ulceribovis type strain IMMIB-L1395(T) (DSM 45146(T))The lipoprotein LpqW is essential for the mannosylation of periplasmic glycolipids in Corynebacteria.Crystallization and preliminary crystallographic analysis of DtsR1, a carboxyltransferase subunit of acetyl-CoA carboxylase from Corynebacterium glutamicum.Identification of a novel alpha(1-->6) mannopyranosyltransferase MptB from Corynebacterium glutamicum by deletion of a conserved gene, NCgl1505, affords a lipomannan- and lipoarabinomannan-deficient mutant.bkaR is a TetR-type repressor that controls an operon associated with branched-chain keto-acid metabolism in Mycobacteria.The influence of AccD5 on AccD6 carboxyltransferase essentiality in pathogenic and non-pathogenic Mycobacterium.
P2860
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P2860
Acyl-CoA carboxylases (accD2 and accD3), together with a unique polyketide synthase (Cg-pks), are key to mycolic acid biosynthesis in Corynebacterianeae such as Corynebacterium glutamicum and Mycobacterium tuberculosis
description
2004 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2004 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
article publié dans la revue scientifique Journal of Biological Chemistry
@fr
artículu científicu espublizáu en 2004
@ast
im Oktober 2004 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2004/10/22)
@sk
vědecký článek publikovaný v roce 2004
@cs
wetenschappelijk artikel (gepubliceerd op 2004/10/22)
@nl
наукова стаття, опублікована в жовтні 2004
@uk
name
Acyl-CoA carboxylases (accD2 a ...... and Mycobacterium tuberculosis
@ast
Acyl-CoA carboxylases (accD2 a ...... and Mycobacterium tuberculosis
@en
Acyl-CoA carboxylases (accD2 a ...... and Mycobacterium tuberculosis
@nl
type
label
Acyl-CoA carboxylases (accD2 a ...... and Mycobacterium tuberculosis
@ast
Acyl-CoA carboxylases (accD2 a ...... and Mycobacterium tuberculosis
@en
Acyl-CoA carboxylases (accD2 a ...... and Mycobacterium tuberculosis
@nl
prefLabel
Acyl-CoA carboxylases (accD2 a ...... and Mycobacterium tuberculosis
@ast
Acyl-CoA carboxylases (accD2 a ...... and Mycobacterium tuberculosis
@en
Acyl-CoA carboxylases (accD2 a ...... and Mycobacterium tuberculosis
@nl
P2093
P2860
P3181
P356
P1476
Acyl-CoA carboxylases (accD2 a ...... and Mycobacterium tuberculosis
@en
P2093
Alistair K Brown
Hermann Sahm
Karin Krumbach
Kevin J C Gibson
Lothar Eggeling
Roland Gande
Susumu Shioyama
Tadao Oikawa
P2860
P304
44847-44857
P3181
P356
10.1074/JBC.M408648200
P407
P577
2004-08-11T00:00:00Z