Spectral characterization of brain and macrophage nitric oxide synthases. Cytochrome P-450-like hemeproteins that contain a flavin semiquinone radical
about
Cloning, characterization, and expression of a cDNA encoding an inducible nitric oxide synthase from the human chondrocyteNitric oxide synthases in mammalsStabilization and characterization of a heme-oxy reaction intermediate in inducible nitric-oxide synthaseSingle Crystal Structural and Absorption Spectral Characterizations of Nitric Oxide Synthase Complexed with N ω -Hydroxy- l -arginine and Diatomic Ligands ,Pterin interactions with distinct reductase activities of NO synthaseA bridging interaction allows calmodulin to activate NO synthase through a bi-modal mechanismQuantitative vibrational dynamics of iron in nitrosyl porphyrins.NADPH-cytochrome P450 oxidoreductase: prototypic member of the diflavin reductase family.Intraprotein electron transfer in inducible nitric oxide synthase holoenzymeRegulation of interdomain electron transfer in the NOS output state for NO productionLys842 in neuronal nitric-oxide synthase enables the autoinhibitory insert to antagonize calmodulin binding, increase FMN shielding, and suppress interflavin electron transferTetrahydrobiopterin in cardiovascular health and disease.Nitric oxide blocks cellular heme insertion into a broad range of heme proteinsCharacterization of key residues in the subdomain encoded by exons 8 and 9 of human inducible nitric oxide synthase: a critical role for Asp-280 in substrate binding and subunit interactions.High-level expression of functional rat neuronal nitric oxide synthase in Escherichia coli.Intraprotein electron transfer between the FMN and heme domains in endothelial nitric oxide synthase holoenzyme.Mutation of Glu-361 in human endothelial nitric-oxide synthase selectively abolishes L-arginine binding without perturbing the behavior of heme and other redox centersSurface charges and regulation of FMN to heme electron transfer in nitric-oxide synthase.Recruitment of governing elements for electron transfer in the nitric oxide synthase familyA conserved flavin-shielding residue regulates NO synthase electron transfer and nicotinamide coenzyme specificityMechanism of Nitric Oxide Synthase Regulation: Electron Transfer and Interdomain Interactions.Identification of redox partners and development of a novel chimeric bacterial nitric oxide synthase for structure activity analysesHeme enzyme structure and function.Mechanistic studies of inactivation of inducible nitric oxide synthase by amidinesArg375 tunes tetrahydrobiopterin functions and modulates catalysis by inducible nitric oxide synthaseHeme coordination of NO in NO synthase.Involvement of nitric oxide in the endothelium-dependent relaxation induced by hydrogen peroxide in the rabbit aortaNitric oxide synthases reveal a role for calmodulin in controlling electron transfer.Metabolism of aminoguanidine, diaminoguanidine, and NG-amino-L-arginine by neuronal NO-synthase and covalent alteration of the heme prosthetic groupIdentification of the tyrosine nitration sites in human endothelial nitric oxide synthase by liquid chromatography-mass spectrometry.A pivotal role for tryptophan 447 in enzymatic coupling of human endothelial nitric oxide synthase (eNOS): effects on tetrahydrobiopterin-dependent catalysis and eNOS dimerizationFast ferrous heme-NO oxidation in nitric oxide synthases.Dissecting regulation mechanism of the FMN to heme interdomain electron transfer in nitric oxide synthases.Mutations in the FMN domain modulate MCD spectra of the heme site in the oxygenase domain of inducible nitric oxide synthase.Complementation analysis of mutants of nitric oxide synthase reveals that the active site requires two hemes.Structures of nitric oxide synthase isoforms complexed with the inhibitor AR-R17477 suggest a rational basis for specificity and inhibitor design.Role of arginine guanidinium moiety in nitric-oxide synthase mechanism of oxygen activation.Purification and characterization of nitric oxide synthase (NOSNoc) from a Nocardia species.Structural analysis of porcine brain nitric oxide synthase reveals a role for tetrahydrobiopterin and L-arginine in the formation of an SDS-resistant dimer.Exploring the electron transfer properties of neuronal nitric-oxide synthase by reversal of the FMN redox potential.
P2860
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P2860
Spectral characterization of brain and macrophage nitric oxide synthases. Cytochrome P-450-like hemeproteins that contain a flavin semiquinone radical
description
1992 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
1992 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
article publié dans la revue scientifique Journal of Biological Chemistry
@fr
artículu científicu espublizáu en 1992
@ast
im Oktober 1992 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 1992/10/15)
@sk
vědecký článek publikovaný v roce 1992
@cs
wetenschappelijk artikel (gepubliceerd op 1992/10/15)
@nl
наукова стаття, опублікована в жовтні 1992
@uk
name
Spectral characterization of b ...... n a flavin semiquinone radical
@ast
Spectral characterization of b ...... n a flavin semiquinone radical
@en
Spectral characterization of b ...... n a flavin semiquinone radical
@nl
type
label
Spectral characterization of b ...... n a flavin semiquinone radical
@ast
Spectral characterization of b ...... n a flavin semiquinone radical
@en
Spectral characterization of b ...... n a flavin semiquinone radical
@nl
prefLabel
Spectral characterization of b ...... n a flavin semiquinone radical
@ast
Spectral characterization of b ...... n a flavin semiquinone radical
@en
Spectral characterization of b ...... n a flavin semiquinone radical
@nl
P921
P1476
Spectral characterization of b ...... n a flavin semiquinone radical
@en
P2093
D. J. Stuehr
M. Ikeda-Saito
P304
20547–20550
P407
P577
1992-10-15T00:00:00Z