Impaired nonhomologous end-joining provokes soft tissue sarcomas harboring chromosomal translocations, amplifications, and deletions
about
Alternative end-joining mechanisms: a historical perspectivePhosphorylation and regulation of DNA ligase IV stability by DNA-dependent protein kinaseWRN interacts physically and functionally with the recombination mediator protein RAD52Oncogenic transformation in the absence of Xrcc4 targets peripheral B cells that have undergone editing and switchingEukaryotic DNA ligases: structural and functional insightsInvolvement of p53 in the repair of DNA double strand breaks: multifaceted Roles of p53 in homologous recombination repair (HRR) and non-homologous end joining (NHEJ)Structural Basis of DNA Ligase IV-Artemis Interaction in Nonhomologous End-JoiningDNA ligase IV syndrome; a reviewNon-homologous end-joining, a sticky affairRegulation of DNA double-strand break repair pathway choiceDNA-dependent protein kinase catalytic subunit is not required for dysfunctional telomere fusion and checkpoint response in the telomerase-deficient mouseSelective utilization of nonhomologous end-joining and homologous recombination DNA repair pathways during nervous system developmentPARP-1 and Ku compete for repair of DNA double strand breaks by distinct NHEJ pathwaysImpaired replication stress response in cells from immunodeficiency patients carrying Cernunnos/XLF mutations.Influence of genetic background on the occurrence of chromosomal rearrangements in Saccharomyces cerevisiae.Mechanism of genomic instability in cells infected with the high-risk human papillomaviruses.ARTEMIS stabilizes the genome and modulates proliferative responses in multipotent mesenchymal cellsHomozygous DNA ligase IV R278H mutation in mice leads to leaky SCID and represents a model for human LIG4 syndromeNon-consensus heptamer sequences destabilize the RAG post-cleavage complex, making ends available to alternative DNA repair pathways.Release of Ku and MRN from DNA ends by Mre11 nuclease activity and Ctp1 is required for homologous recombination repair of double-strand breaks.Short inverted repeats initiate gene amplification through the formation of a large DNA palindrome in mammalian cells.Components of the Rb pathway are critical targets of UV mutagenesis in a murine melanoma model.Relevance of LIG4 gene polymorphisms with cancer susceptibility: evidence from a meta-analysisTargeting abnormal DNA double strand break repair in cancerXRCC4 suppresses medulloblastomas with recurrent translocations in p53-deficient mice.Genetic polymorphisms of DNA double-strand break repair pathway genes and glioma susceptibility.DNA repair mechanisms in dividing and non-dividing cells.A mouse model of human oral-esophageal cancer.Developmental modulation of nonhomologous end joining in Caenorhabditis elegans.Mechanisms of sarcoma development.Human Mre11/human Rad50/Nbs1 and DNA ligase IIIalpha/XRCC1 protein complexes act together in an alternative nonhomologous end joining pathwayRegulatory networks integrating cell cycle control with DNA damage checkpoints and double-strand break repair.Electron microscopy visualization of DNA-protein complexes formed by Ku and DNA ligase IV2-Step purification of the Ku DNA repair protein expressed in Escherichia coli.Repair of radiation damage to DNA.The DNA-dependent protein kinase: the director at the end.Cell cycle- and DNA repair pathway-specific effects of apoptosis on tumor suppression.Tumor suppressor genetics.Evidence for replicative repair of DNA double-strand breaks leading to oncogenic translocation and gene amplification.Clonal and non-clonal chromosome aberrations and genome variation and aberration.
P2860
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P2860
Impaired nonhomologous end-joining provokes soft tissue sarcomas harboring chromosomal translocations, amplifications, and deletions
description
2001 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2001
@ast
im Dezember 2001 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2001/12/01)
@sk
vědecký článek publikovaný v roce 2001
@cs
wetenschappelijk artikel (gepubliceerd op 2001/12/01)
@nl
наукова стаття, опублікована в грудні 2001
@uk
مقالة علمية (نشرت في ديسمبر 2001)
@ar
name
Impaired nonhomologous end-joi ...... amplifications, and deletions
@ast
Impaired nonhomologous end-joi ...... amplifications, and deletions
@en
Impaired nonhomologous end-joi ...... amplifications, and deletions
@nl
type
label
Impaired nonhomologous end-joi ...... amplifications, and deletions
@ast
Impaired nonhomologous end-joi ...... amplifications, and deletions
@en
Impaired nonhomologous end-joi ...... amplifications, and deletions
@nl
prefLabel
Impaired nonhomologous end-joi ...... amplifications, and deletions
@ast
Impaired nonhomologous end-joi ...... amplifications, and deletions
@en
Impaired nonhomologous end-joi ...... amplifications, and deletions
@nl
P2093
P3181
P1433
P1476
Impaired nonhomologous end-joi ...... amplifications, and deletions
@en
P2093
C C Morton
D H Castrillon
D O Ferguson
P A Farazi
R A DePinho
P304
P3181
P356
10.1016/S1097-2765(01)00425-7
P577
2001-12-01T00:00:00Z