Src and Pyk2 mediate G-protein-coupled receptor activation of epidermal growth factor receptor (EGFR) but are not required for coupling to the mitogen-activated protein (MAP) kinase signaling cascade
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International Union of Pharmacology LVIII: update on the P2Y G protein-coupled nucleotide receptors: from molecular mechanisms and pathophysiology to therapySrc kinase becomes preferentially associated with the VEGFR, KDR/Flk-1, following VEGF stimulation of vascular endothelial cells.Cell-surface receptors transactivation mediated by g protein-coupled receptorsHeparin-binding epidermal growth factor-like growth factor/diphtheria toxin receptor in normal and neoplastic hematopoiesisHarnessing the genome for characterization of G-protein coupled receptors in cancer pathogenesisUnravelling the molecular complexity of GPCR-mediated EGFR transactivation using functional genomics approachesSignal transduction of physiological concentrations of vasopressin in A7r5 vascular smooth muscle cells. A role for PYK2 and tyrosine phosphorylation of K+ channels in the stimulation of Ca2+ spikingChronic ethanol feeding impairs endothelin-1-stimulated glucose uptake via decreased G alpha 11 expression in rat adipocytesIL-1 beta induces proMMP-9 expression via c-Src-dependent PDGFR/PI3K/Akt/p300 cascade in rat brain astrocytesSrc homology 3 binding sites in the P2Y2 nucleotide receptor interact with Src and regulate activities of Src, proline-rich tyrosine kinase 2, and growth factor receptors.Lysophosphatidic acid 5 receptor induces activation of Na(+)/H(+) exchanger 3 via apical epidermal growth factor receptor in intestinal epithelial cellsCXCL12 and [N33A]CXCL12 in 5637 and HeLa cells: regulating HER1 phosphorylation via calmodulin/calcineurin.Multiple actions of lysophosphatidic acid on fibroblasts revealed by transcriptional profilingImpaired NK-cell migration in WAS/XLT patients: role of Cdc42/WASp pathway in the control of chemokine-induced beta2 integrin high-affinity stateThe role of endogenous epidermal growth factor receptor ligands in mediating corneal epithelial homeostasis.AICAR and metformin, but not exercise, increase muscle glucose transport through AMPK-, ERK-, and PDK1-dependent activation of atypical PKC.GnRH-(1-5) transactivates EGFR in Ishikawa human endometrial cells via an orphan G protein-coupled receptorCardiovascular actions of neurotrophinsPyk2 activation triggers epidermal growth factor receptor signaling and cell motility after wounding sheets of epithelial cells.Clostridium difficile toxin B differentially affects GPCR-stimulated Ca2+ responses in macrophages: independent roles for Rho and PLA2.Self-reinforcing loop of amphiregulin and Y-box binding protein-1 contributes to poor outcomes in ovarian cancer.Role of protein kinase C and epidermal growth factor receptor signalling in growth stimulation by neurotensin in colon carcinoma cells.Galpha and Gbeta gamma require distinct Src-dependent pathways to activate Rap1 and Ras.Role of sphingosine-1-phosphate phosphatase 1 in epidermal growth factor-induced chemotaxis.Noncanonical G-protein-dependent modulation of osteoclast differentiation and bone resorption mediated by Pasteurella multocida toxinDiversity of G protein-coupled receptor signaling pathways to ERK/MAP kinaseDistinct mechanisms of receptor and nonreceptor tyrosine kinase activation by reactive oxygen species in vascular smooth muscle cells: role of metalloprotease and protein kinase C-deltaCigarette smoke extract induces COX-2 expression via a PKCalpha/c-Src/EGFR, PDGFR/PI3K/Akt/NF-kappaB pathway and p300 in tracheal smooth muscle cells.Follicle-stimulating hormone activates extracellular signal-regulated kinase but not extracellular signal-regulated kinase kinase through a 100-kDa phosphotyrosine phosphatase12/15-Lipoxygenase-dependent ROS production is required for diet-induced endothelial barrier dysfunction.erbB2 is required for G protein-coupled receptor signaling in the heart.TNF transactivation of EGFR stimulates cytoprotective COX-2 expression in gastrointestinal epithelial cells.Extracellular ATP stimulates epithelial cell motility through Pyk2-mediated activation of the EGF receptorDifferential expression of FAK and Pyk2 in metastatic and non-metastatic EL4 lymphoma cell linesAlpha1a-Adrenoceptor Genetic Variant Triggers Vascular Smooth Muscle Cell Hyperproliferation and Agonist Induced Hypertrophy via EGFR Transactivation Pathway.Striatal-enriched protein-tyrosine phosphatase (STEP) regulates Pyk2 kinase activity.Tri-nucleotide receptors play a critical role in epithelial cell wound repair.International Union of Basic and Clinical Pharmacology. XCIX. Angiotensin Receptors: Interpreters of Pathophysiological Angiotensinergic Stimuli [corrected].Involvement of Protein Kinase D1 in Signal Transduction from the Protein Kinase C Pathway to the Tyrosine Kinase Pathway in Response to Gonadotropin-releasing HormonePYK2: a calcium-sensitive protein tyrosine kinase activated in response to fertilization of the zebrafish oocyte.
P2860
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P2860
Src and Pyk2 mediate G-protein-coupled receptor activation of epidermal growth factor receptor (EGFR) but are not required for coupling to the mitogen-activated protein (MAP) kinase signaling cascade
description
2001 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի հունիսին հրատարակված գիտական հոդված
@hy
article publié dans la revue scientifique Journal of Biological Chemistry
@fr
artículu científicu espublizáu en 2001
@ast
im Juni 2001 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2001/06/08)
@sk
vědecký článek publikovaný v roce 2001
@cs
wetenschappelijk artikel (gepubliceerd op 2001/06/08)
@nl
наукова стаття, опублікована в червні 2001
@uk
name
Src and Pyk2 mediate G-protein ...... (MAP) kinase signaling cascade
@ast
Src and Pyk2 mediate G-protein ...... (MAP) kinase signaling cascade
@en
Src and Pyk2 mediate G-protein ...... (MAP) kinase signaling cascade
@nl
type
label
Src and Pyk2 mediate G-protein ...... (MAP) kinase signaling cascade
@ast
Src and Pyk2 mediate G-protein ...... (MAP) kinase signaling cascade
@en
Src and Pyk2 mediate G-protein ...... (MAP) kinase signaling cascade
@nl
prefLabel
Src and Pyk2 mediate G-protein ...... (MAP) kinase signaling cascade
@ast
Src and Pyk2 mediate G-protein ...... (MAP) kinase signaling cascade
@en
Src and Pyk2 mediate G-protein ...... (MAP) kinase signaling cascade
@nl
P2093
P2860
P921
P3181
P356
P1476
Src and Pyk2 mediate G-protein ...... (MAP) kinase signaling cascade
@en
P2093
E. S. Chiu
J. Andreev
J. Schlessinger
L. A. Cary
M. L. Galisteo
M. Okigaki
O. Kranenburg
S. K. Logan
W. H. Moolenaar
P2860
P304
20130–20135
P3181
P356
10.1074/JBC.M102307200
P407
P577
2001-06-08T00:00:00Z