Beta-cell-specific ablation of the hepatocyte growth factor receptor results in reduced islet size, impaired insulin secretion, and glucose intolerance
about
Loss of sugar detection by GLUT2 affects glucose homeostasis in miceThe discovery of hepatocyte growth factor (HGF) and its significance for cell biology, life sciences and clinical medicinec-Met signaling in the development of tumorigenesis and chemoresistance: potential applications in pancreatic cancerLoss of HGF/c-Met signaling in pancreatic β-cells leads to incomplete maternal β-cell adaptation and gestational diabetes mellitus.Disruption of hepatocyte growth factor/c-Met signaling enhances pancreatic beta-cell death and accelerates the onset of diabetesHepatocyte growth factor signaling ameliorates podocyte injury and proteinuria.Placental insufficiency decreases pancreatic vascularity and disrupts hepatocyte growth factor signaling in the pancreatic islet endothelial cell in fetal sheepDynamic expression and localization of c-MET isoforms in the developing rat pancreas.Epigenetic regulation of the lncRNA MEG3 and its target c-MET in pancreatic neuroendocrine tumors.Hepatocyte growth factor attenuates liver fibrosis induced by bile duct ligationhepatocyte growth factor is a downstream effector that mediates the antifibrotic action of peroxisome proliferator-activated receptor-gamma agonists.Suppression of tumor invasion and metastasis by concurrent inhibition of c-Met and VEGF signaling in pancreatic neuroendocrine tumorsThe MET Receptor Tyrosine Kinase Confers Repair of Murine Pancreatic Acinar Cells following Acute and Chronic Injury.Chitosan-assisted differentiation of porcine adipose tissue-derived stem cells into glucose-responsive insulin-secreting clusters.Human umbilical cord matrix-derived stem cells exert trophic effects on β-cell survival in diabetic rats and isolated islets.Activation of hepatocyte growth factor receptor, c-met, in renal tubules is required for renoprotection after acute kidney injury.Hepatocyte growth factor twenty years on: Much more than a growth factor.Hepatocyte growth factor and Met in drug discovery.Promise and challenges on the horizon of MET-targeted cancer therapeuticsPancreatic islet hepatocyte growth factor and vascular endothelial growth factor A signaling in growth restricted fetuses.Molecular magnetic resonance imaging approaches used to aid in the understanding of the tissue regeneration marker Met in vivo: implications for tissue engineering.Partial-Hepatectomized (70%) Model Shows a Correlation between Hepatocyte Growth Factor Levels and Beta-Cell Mass.Adult-onset deletion of Pten increases islet mass and beta cell proliferation in mice.PTEN controls β-cell regeneration in aged mice by regulating cell cycle inhibitor p16ink4a.Lack of beta-catenin in early life induces abnormal glucose homeostasis in mice.Biological roles of hepatocyte growth factor-Met signaling from genetically modified animals.HGF-Met Pathway in Regeneration and Drug Discovery.
P2860
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P2860
Beta-cell-specific ablation of the hepatocyte growth factor receptor results in reduced islet size, impaired insulin secretion, and glucose intolerance
description
2005 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2005
@ast
im August 2005 veröffentlichter wissenschaftlicher Artikel
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scientific journal article
@en
vedecký článok (publikovaný 2005/08/01)
@sk
vědecký článek publikovaný v roce 2005
@cs
wetenschappelijk artikel (gepubliceerd op 2005/08/01)
@nl
наукова стаття, опублікована в серпні 2005
@uk
مقالة علمية (نشرت في أغسطس 2005)
@ar
name
Beta-cell-specific ablation of ...... etion, and glucose intolerance
@ast
Beta-cell-specific ablation of ...... etion, and glucose intolerance
@en
Beta-cell-specific ablation of ...... etion, and glucose intolerance
@nl
type
label
Beta-cell-specific ablation of ...... etion, and glucose intolerance
@ast
Beta-cell-specific ablation of ...... etion, and glucose intolerance
@en
Beta-cell-specific ablation of ...... etion, and glucose intolerance
@nl
prefLabel
Beta-cell-specific ablation of ...... etion, and glucose intolerance
@ast
Beta-cell-specific ablation of ...... etion, and glucose intolerance
@en
Beta-cell-specific ablation of ...... etion, and glucose intolerance
@nl
P2093
P2860
P921
P3181
P1476
Beta-cell-specific ablation of ...... etion, and glucose intolerance
@en
P2093
Chang-Goo Huh
Chunsun Dai
Snorri S. Thorgeirsson
Youhua Liu
P2860
P304
P3181
P356
10.1016/S0002-9440(10)62987-2
P407
P577
2005-08-01T00:00:00Z