hepatocyte growth factor is a downstream effector that mediates the antifibrotic action of peroxisome proliferator-activated receptor-gamma agonists. - Wikidata - wikimedia - TriplyDB

hepatocyte growth factor is a downstream effector that mediates the antifibrotic action of peroxisome proliferator-activated receptor-gamma agonists.

hepatocyte growth factor is a downstream effector that mediates the antifibrotic action of peroxisome proliferator-activated receptor-gamma agonists.

http://www.wikidata.org/entity/Q35677086

about

Opposite action of peroxisome proliferator-activated receptor-gamma in regulating renal inflammation: functional switch by its ligand New molecular medicine-based scar management strategies Hepatocyte Growth Factor Prevented High-Fat Diet-Induced Obesity and Improved Insulin Resistance in Mice.ID2 predicts poor prognosis in breast cancer, especially in triple-negative breast cancer, and inhibits E-cadherin expression Hepatocyte growth factor, a biomarker of macroangiopathy in diabetes mellitus.Rosiglitazone inhibits transforming growth factor-β1 mediated fibrogenesis in ADPKD cyst-lining epithelial cells.Mouse hepatic oval cells require Met-dependent PI3K to impair TGF-β-induced oxidative stress and apoptosis.Neuroprotectin/protectin D1: endogenous biosynthesis and actions on diabetic macrophages in promoting wound healing and innervation impaired by diabetes.tPA protects renal interstitial fibroblasts and myofibroblasts from apoptosis Progression of glomerular and tubular disease in pediatrics.The PPARγ Agonist Rosiglitazone Is Antifibrotic for Scleroderma Lung Fibroblasts: Mechanisms of Action and Differential Racial Effects.The Role of PPARs in Lung Fibrosis.Peroxisome proliferator-activated receptor γ: innate protection from excessive fibrogenesis and potential therapeutic target in systemic sclerosis Regulation of Matrix Remodeling by Peroxisome Proliferator-Activated Receptor-γ: A Novel Link Between Metabolism and Fibrogenesis.Tissue-type plasminogen activator promotes murine myofibroblast activation through LDL receptor-related protein 1-mediated integrin signaling PPARγ activation following apoptotic cell instillation promotes resolution of lung inflammation and fibrosis via regulation of efferocytosis and proresolving cytokines.Rapid Identification of Potential Drugs for Diabetic Nephropathy Using Whole-Genome Expression Profiles of Glomeruli.A Novel Mechanism of PPARgamma Regulation of TGFbeta1: Implication in Cancer Biology Cardiac and renal protective effects of irbesartan via peroxisome proliferator-activated receptorγ-hepatocyte growth factor pathway independent of angiotensin II Type 1a receptor blockade in mouse model of salt-sensitive hypertension Rosiglitazone abrogates bleomycin-induced scleroderma and blocks profibrotic responses through peroxisome proliferator-activated receptor-gamma PPARs and the kidney in metabolic syndrome.Racial differences between blacks and whites with systemic sclerosis Renal interstitial cells, proteinuria and progression of lupus nephritis: new frontiers for old factors.Peroxisome proliferator-activated receptor-gamma abrogates Smad-dependent collagen stimulation by targeting the p300 transcriptional coactivator.Inhibition of integrin-linked kinase attenuates renal interstitial fibrosis.TGF-beta signal transduction in chronic kidney disease Madecassoside ameliorates bleomycin-induced pulmonary fibrosis in mice through promoting the generation of hepatocyte growth factor via PPAR-γ in colon.PPAR modulation of kinase-linked receptor signaling in physiology and disease.PPARγ and chronic kidney disease.PAI-1 in tissue fibrosis.Improvement of metabolic syndrome by irbesartan via the PPARγ/HGF pathway in apolipoprotein E knockout mice.Electrophilic peroxisome proliferator-activated receptor-gamma ligands have potent antifibrotic effects in human lung fibroblasts.Mesenchymal Stem/Stromal Cells in Liver Fibrosis: Recent Findings, Old/New Caveats and Future Perspectives.The Role of PPAR Gamma in Systemic Sclerosis.The emerging role of hepatocyte growth factor in renal diseases.MiRNA-200b represses transforming growth factor-β1-induced EMT and fibronectin expression in kidney proximal tubular cells.Antifibrotic effect by activation of peroxisome proliferator-activated receptor-gamma in corneal fibroblasts.PPARgamma agonists prevent TGFbeta1/Smad3-signaling in human hepatic stellate cells.PPARgamma agonist and angiotensin II receptor antagonist ameliorate renal tubulointerstitial fibrosis.Correlation between TSP-1, TGF-β and PPAR-γ expression levels and glioma microvascular density.

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P2860

hepatocyte growth factor is a downstream effector that mediates the antifibrotic action of peroxisome proliferator-activated receptor-gamma agonists.

http://www.wikidata.org/entity/Q35677086

description

2005 nî lūn-bûn

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Journal of the American Society of Nephrology

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P2093

Bradley C Spataro

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Chunsun Dai

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Kebin Hu

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Xiaoyan Wen

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Yingjian Li

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Youhua Liu

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P2860

Epithelial-mesenchymal transition and its implications for fibrosis

TGF-beta signal transduction and mesangial cell fibrogenesis

Sustained expression of naked plasmid DNA encoding hepatocyte growth factor in mice promotes liver and overall body growth

The organization, promoter analysis, and expression of the human PPARgamma gene

Placental defect and embryonic lethality in mice lacking hepatocyte growth factor/scatter factor

Expression of peroxisomal proliferator-activated receptors and retinoid X receptors in the kidney

Beta-cell-specific ablation of the hepatocyte growth factor receptor results in reduced islet size, impaired insulin secretion, and glucose intolerance

Hepatocyte growth factor antagonizes the profibrotic action of TGF-beta1 in mesangial cells by stabilizing Smad transcriptional corepressor TGIF

Primary structure of rat HGF receptor and induced expression in glomerular mesangial cells

PPAR gamma is required for placental, cardiac, and adipose tissue development

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54-65

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10.1681/ASN.2005030257

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1

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17

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1820837

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