RORgammat recruits steroid receptor coactivators to ensure thymocyte survival
about
β-catenin/TCF-1 pathway in T cell development and differentiationThe therapeutic potential of RORγ modulators in the treatment of human diseaseIdentification of Tetraazacyclic Compounds as Novel Potent Inhibitors Antagonizing RORγt Activity and Suppressing Th17 Cell DifferentiationT cell factor 1 regulates thymocyte survival via a RORγt-dependent pathwayId1 induces apoptosis through inhibition of RORgammat expressionRetinoid-related Orphan Receptors (RORs): Roles in Cellular Differentiation and Development.Retinoid-related orphan receptors (RORs): critical roles in development, immunity, circadian rhythm, and cellular metabolismUrsolic acid suppresses interleukin-17 (IL-17) production by selectively antagonizing the function of RORgamma t proteinInhibition of RORγt activity and Th17 differentiation by a set of novel compounds.Structural determinant for inducing RORgamma specific inverse agonism triggered by a synthetic benzoxazinone ligand.A critical role for protein kinase C-theta-mediated T cell survival in cardiac allograft rejection.Differential requirement of PKC-theta in the development and function of natural regulatory T cells.Molecular mechanisms that control mouse and human TCR-alphabeta and TCR-gammadelta T cell development.Developing and activated T cell survival depends on differential signaling pathways to regulate anti-apoptotic Bcl-x(L).Yin-Yang Regulation of RORγt Protein Complex in Th17 Differentiation.Autophagy-related intrinsically disordered proteins in intra-nuclear compartments.Ubiquitination of RORγt at Lysine 446 Limits Th17 Differentiation by Controlling Coactivator Recruitment.The roles of CCR6 in migration of Th17 cells and regulation of effector T-cell balance in the gut.Regulation of Th17 Differentiation by IKKα-Dependent and -Independent Phosphorylation of RORγt.A two-amino-acid substitution in the transcription factor RORγt disrupts its function in TH17 differentiation but not in thymocyte development.Pharmacological inhibition of RORγt suppresses the Th17 pathway and alleviates arthritis in vivo.SRC1 promotes Th17 differentiation by overriding Foxp3 suppression to stimulate RORγt activity in a PKC-θ-dependent manner.Sumoylation of RORγt regulates T17 differentiation and thymocyte development
P2860
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P2860
RORgammat recruits steroid receptor coactivators to ensure thymocyte survival
description
2005 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2005
@ast
im September 2005 veröffentlichter wissenschaftlicher Artikel
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scientific journal article
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vedecký článok (publikovaný 2005/09/15)
@sk
vědecký článek publikovaný v roce 2005
@cs
wetenschappelijk artikel (gepubliceerd op 2005/09/15)
@nl
наукова стаття, опублікована у вересні 2005
@uk
مقالة علمية (نشرت في 15-9-2005)
@ar
name
RORgammat recruits steroid receptor coactivators to ensure thymocyte survival
@ast
RORgammat recruits steroid receptor coactivators to ensure thymocyte survival
@en
RORgammat recruits steroid receptor coactivators to ensure thymocyte survival
@nl
type
label
RORgammat recruits steroid receptor coactivators to ensure thymocyte survival
@ast
RORgammat recruits steroid receptor coactivators to ensure thymocyte survival
@en
RORgammat recruits steroid receptor coactivators to ensure thymocyte survival
@nl
prefLabel
RORgammat recruits steroid receptor coactivators to ensure thymocyte survival
@ast
RORgammat recruits steroid receptor coactivators to ensure thymocyte survival
@en
RORgammat recruits steroid receptor coactivators to ensure thymocyte survival
@nl
P2093
P3181
P1476
RORgammat recruits steroid receptor coactivators to ensure thymocyte survival
@en
P2093
Huimin Xie
Maureen S. Sadim
Zuoming Sun
P304
P3181
P356
10.4049/JIMMUNOL.175.6.3800
P407
P577
2005-09-15T00:00:00Z