SUMO-specific protease 2 is essential for modulating p53-Mdm2 in development of trophoblast stem cell niches and lineages
about
SUMOylation of hnRNP-K is required for p53-mediated cell-cycle arrest in response to DNA damageAdvances in the development of SUMO specific protease (SENP) inhibitorsRegulation of epithelial-mesenchymal transition through SUMOylation of transcription factorsDisruption of SUMO-specific protease 2 induces mitochondria mediated neurodegenerationSUMO-specific protease 2 is essential for suppression of polycomb group protein-mediated gene silencing during embryonic development.Reciprocal regulation of Wnt and Gpr177/mouse Wntless is required for embryonic axis formationSUMO-specific protease 2 in Mdm2-mediated regulation of p53De-SUMOylation enzyme of sentrin/SUMO-specific protease 2 regulates disturbed flow-induced SUMOylation of ERK5 and p53 that leads to endothelial dysfunction and atherosclerosis.Gpr177 deficiency impairs mammary development and prohibits Wnt-induced tumorigenesis.Increased epithelial stem cell traits in advanced endometrial endometrioid carcinoma.Manipulating gene activity in Wnt1-expressing precursors of neural epithelial and neural crest cells.SUMO-4: A novel functional candidate in the human placental protein SUMOylation machinery.The RNA-binding protein hnRNPLL induces a T cell alternative splicing program delineated by differential intron retention in polyadenylated RNA.Dysregulation of promyelocytic leukemia (PML) protein expression in preeclamptic placentae.Genes and signals regulating murine trophoblast cell developmentExpression of Gpr177, a Wnt trafficking regulator, in mouse embryogenesisThe balance of WNT and FGF signaling influences mesenchymal stem cell fate during skeletal development.Induction of SENP1 in endothelial cells contributes to hypoxia-driven VEGF expression and angiogenesis.Epidermal Wnt controls hair follicle induction by orchestrating dynamic signaling crosstalk between the epidermis and dermis.SUMOylation represses Nanog expression via modulating transcription factors Oct4 and Sox2SUMO--a post-translational modification with therapeutic potential?Gpr177/mouse Wntless is essential for Wnt-mediated craniofacial and brain development.Cardiac function and disease: emerging role of small ubiquitin-related modifier.Derivation of mouse trophoblast stem cells from blastocysts.A novel cyclic AMP/Epac1/CaMKI signaling cascade promotes GCM1 desumoylation and placental cell fusion.SUMO-Specific Protease 2 (SENP2) Is an Important Regulator of Fatty Acid Metabolism in Skeletal Muscle.Enhanced desumoylation in murine hearts by overexpressed SENP2 leads to congenital heart defects and cardiac dysfunction.Mechanisms of p53 activation and physiological relevance in the developing kidney.The E3 ligase APC/C-Cdh1 regulates MEF2A-dependent transcription by targeting SUMO-specific protease 2 for ubiquitination and degradation.FGF inhibition directs BMP4-mediated differentiation of human embryonic stem cells to syncytiotrophoblast.Transcriptional Profile and Structural Conservation of SUMO-Specific Proteases in Schistosoma mansoni.Stem cells of the suture mesenchyme in craniofacial bone development, repair and regeneration.Extraembryonic but not embryonic SUMO-specific protease 2 is required for heart development.Gpr177, a novel locus for bone mineral density and osteoporosis, regulates osteogenesis and chondrogenesis in skeletal developmentTwo distinct sites in Nup153 mediate interaction with the SUMO proteases SENP1 and SENP2.Sumoylation and regulation of cardiac gene expression.Altered gene expression and spongiotrophoblast differentiation in placenta from a mouse model of diabetes in pregnancy.An essential role of small ubiquitin-like modifier (SUMO)-specific Protease 2 in myostatin expression and myogenesis.Transcriptional repression of estrogen receptor α signaling by SENP2 in breast cancer cells.SUMO Losing Balance: SUMO Proteases Disrupt SUMO Homeostasis to Facilitate Cancer Development and Progression.
P2860
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P2860
SUMO-specific protease 2 is essential for modulating p53-Mdm2 in development of trophoblast stem cell niches and lineages
description
2008 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2008
@ast
im Dezember 2008 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2008/12/16)
@sk
vědecký článek publikovaný v roce 2008
@cs
wetenschappelijk artikel (gepubliceerd op 2008/12/16)
@nl
наукова стаття, опублікована в грудні 2008
@uk
مقالة علمية (نشرت في 16-12-2008)
@ar
name
SUMO-specific protease 2 is es ...... stem cell niches and lineages
@ast
SUMO-specific protease 2 is es ...... stem cell niches and lineages
@en
SUMO-specific protease 2 is es ...... stem cell niches and lineages
@nl
type
label
SUMO-specific protease 2 is es ...... stem cell niches and lineages
@ast
SUMO-specific protease 2 is es ...... stem cell niches and lineages
@en
SUMO-specific protease 2 is es ...... stem cell niches and lineages
@nl
prefLabel
SUMO-specific protease 2 is es ...... stem cell niches and lineages
@ast
SUMO-specific protease 2 is es ...... stem cell niches and lineages
@en
SUMO-specific protease 2 is es ...... stem cell niches and lineages
@nl
P2093
P2860
P3181
P1433
P1476
SUMO-specific protease 2 is es ...... stem cell niches and lineages
@en
P2093
Frank Costantini
Naoya Asai
Shang-Yi Chiu
P2860
P3181
P356
10.1371/JOURNAL.PBIO.0060310
P407
P50
P577
2008-12-16T00:00:00Z