A neurotoxic peripherin splice variant in a mouse model of ALS
about
GFAP and its role in Alexander diseaseDysfunctions of neuronal and glial intermediate filaments in diseaseOxr1 improves pathogenic cellular features of ALS-associated FUS and TDP-43 mutationsA two-hybrid screen identifies an unconventional role for the intermediate filament peripherin in regulating the subcellular distribution of the SNAP25-interacting protein, SIP30Identification of novel susceptibility loci for Guam neurodegenerative disease: challenges of genome scans in genetic isolates.Global gene expression profiling of somatic motor neuron populations with different vulnerability identify molecules and pathways of degeneration and protectionTranscriptional profile of primary astrocytes expressing ALS-linked mutant SOD1.Syncoilin modulates peripherin filament networks and is necessary for large-calibre motor neurons.A frameshift deletion in peripherin gene associated with amyotrophic lateral sclerosis.The cytoskeleton in neurodegenerative diseases.Charcot-Marie-Tooth type 2B disease-causing RAB7A mutant proteins show altered interaction with the neuronal intermediate filament peripherin.Withaferin A effectively targets soluble vimentin in the glaucoma filtration surgical model of fibrosis.Protein kinase Cepsilon binds peripherin and induces its aggregation, which is accompanied by apoptosis of neuroblastoma cells.Molecular and cellular pathways of neurodegeneration in motor neurone diseaseLow molecular weight species of TDP-43 generated by abnormal splicing form inclusions in amyotrophic lateral sclerosis and result in motor neuron death.Oxidants induce alternative splicing of alpha-synuclein: Implications for Parkinson's disease.Amyotrophic lateral sclerosis: contemporary concepts in etiopathogenesis and pharmacotherapy.From Transcriptome to Noncoding RNAs: Implications in ALS Mechanism.Algal Toxin Azaspiracid-1 Induces Early Neuronal Differentiation and Alters Peripherin Isoform Stoichiometry.Noncoding RNAs and RNA editing in brain development, functional diversification, and neurological disease.PATHOLOGIES OF AXONAL TRANSPORT IN NEURODEGENERATIVE DISEASESGenetics of amyotrophic lateral sclerosis: an update.Management of amyotrophic lateral sclerosis (ALS) by the family nurse practitioner: a timeline for anticipated referrals.Neurofilament dynamics and involvement in neurological disorders.Mutant SOD1 and mitochondrial damage alter expression and splicing of genes controlling neuritogenesis in models of neurodegeneration.ALS mouse model SOD1G93A displays early pathology of sensory small fibers associated to accumulation of a neurotoxic splice variant of peripherin.A novel peripherin isoform generated by alternative translation is required for normal filament network formation.Defective axonal transport of neurofilament proteins in neurons overexpressing peripherin.Mutant copper-zinc superoxide dismutase binds to and destabilizes human low molecular weight neurofilament mRNA.Comparative analysis of genetic modifiers in Drosophila points to common and distinct mechanisms of pathogenesis among polyglutamine diseases.Type III Intermediate Filaments Desmin, Glial Fibrillary Acidic Protein (GFAP), Vimentin, and Peripherin.Pathological hallmarks of amyotrophic lateral sclerosis/frontotemporal lobar degeneration in transgenic mice produced with TDP-43 genomic fragments.THEME 9IN VIVOEXPERIMENTAL MODELS
P2860
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P2860
A neurotoxic peripherin splice variant in a mouse model of ALS
description
2003 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի մարտին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2003
@ast
im März 2003 veröffentlichter wissenschaftlicher Artikel
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scientific journal article
@en
vedecký článok (publikovaný 2003/03/17)
@sk
vědecký článek publikovaný v roce 2003
@cs
wetenschappelijk artikel (gepubliceerd op 2003/03/17)
@nl
наукова стаття, опублікована в березні 2003
@uk
مقالة علمية (نشرت في 17-3-2003)
@ar
name
A neurotoxic peripherin splice variant in a mouse model of ALS
@ast
A neurotoxic peripherin splice variant in a mouse model of ALS
@en
A neurotoxic peripherin splice variant in a mouse model of ALS
@nl
type
label
A neurotoxic peripherin splice variant in a mouse model of ALS
@ast
A neurotoxic peripherin splice variant in a mouse model of ALS
@en
A neurotoxic peripherin splice variant in a mouse model of ALS
@nl
prefLabel
A neurotoxic peripherin splice variant in a mouse model of ALS
@ast
A neurotoxic peripherin splice variant in a mouse model of ALS
@en
A neurotoxic peripherin splice variant in a mouse model of ALS
@nl
P2093
P2860
P921
P356
P1476
A neurotoxic peripherin splice variant in a mouse model of ALS
@en
P2093
Gerry Shaw
Heather D. Durham
Janice Robertson
Jean-Pierre Julien
Michael J. Strong
Minh Dang Nguyen
Mohammad M. Doroudchi
Walter E. Mushynski
P2860
P304
P356
10.1083/JCB.200205027
P407
P577
2003-03-17T00:00:00Z