Cross-talk among ROR alpha 1 and the Rev-erb family of orphan nuclear receptors
about
The orphan nuclear receptor ROR alpha is a negative regulator of the inflammatory responseA functional Rev-erb alpha responsive element located in the human Rev-erb alpha promoter mediates a repressing activityThe nuclear receptor Rev-erbalpha is a liver X receptor (LXR) target gene driving a negative feedback loop on select LXR-induced pathways in human macrophagesTwo receptor interaction domains in the corepressor, N-CoR/RIP13, are required for an efficient interaction with Rev-erbA alpha and RVR: physical association is dependent on the E region of the orphan receptorsFunctional analysis of retinoid Z receptor beta, a brain-specific nuclear orphan receptorTranscriptional activation of the nuclear receptor RZR alpha by the pineal gland hormone melatonin and identification of CGP 52608 as a synthetic ligandIdentification of heme as the ligand for the orphan nuclear receptors REV-ERBalpha and REV-ERBbeta.RORgamma t, a novel isoform of an orphan receptor, negatively regulates Fas ligand expression and IL-2 production in T cellsNuclear receptors and AMPK: resetting metabolismRole of Nuclear Receptors in Central Nervous System Development and Associated DiseasesThe Structural Basis of Gas-Responsive Transcription by the Human Nuclear Hormone Receptor REV-ERBβNuclear receptor Rev-erbalpha: a heme receptor that coordinates circadian rhythm and metabolismCharacterization of the core mammalian clock component, NPAS2, as a REV-ERBalpha/RORalpha target geneExpression of AFP and Rev-Erb A/Rev-Erb B and N-CoR in fetal rat liver, liver injury and liver regenerationThe orphan nuclear receptor RORalpha restrains adipocyte differentiation through a reduction of C/EBPbeta activity and perilipin gene expressionIdentification of inherited genetic variations influencing prognosis in early-onset breast cancerRetinoic acid actions through mammalian nuclear receptors.Molecular signatures reveal circadian clocks may orchestrate the homeorhetic response to lactationRev-erbalpha2 mRNA encodes a stable protein with a potential role in circadian clock regulationNuclear hormone receptors for heme: REV-ERBalpha and REV-ERBbeta are ligand-regulated components of the mammalian clock.Conserved genes act as modifiers of invertebrate SMN loss of function defectsThe nuclear receptor gene family in the Pacific oyster, Crassostrea gigas, contains a novel subfamily groupInteractions of the crustacean nuclear receptors HR3 and E75 in the regulation of gene transcription.Novel mechanism of nuclear receptor corepressor interaction dictated by activation function 2 helix determinants.Action of RORs and their ligands in (patho)physiology.REV-ERB and ROR nuclear receptors as drug targets.Transcriptional repression by Rev-erbA alpha is dependent on the signature motif and helix 5 in the ligand binding domain: silencing does not involve an interaction with N-CoR.Transcriptional repression by the orphan steroid receptor RVR/Rev-erb beta is dependent on the signature motif and helix 5 in the E region: functional evidence for a biological role of RVR in myogenesis.The orphan Rev-erb nuclear receptors: a link between metabolism, circadian rhythm and inflammation?Retinoid-related Orphan Receptors (RORs): Roles in Cellular Differentiation and Development.Retinoid-related orphan receptors (RORs): critical roles in development, immunity, circadian rhythm, and cellular metabolismstaggerer phenotype in retinoid-related orphan receptor alpha-deficient mice.GENE REGULATION. Discrete functions of nuclear receptor Rev-erbα couple metabolism to the clock.Nuclear hormone receptor CHR3 is a critical regulator of all four larval molts of the nematode Caenorhabditis elegansDifferential display of DNA-binding proteins reveals heat-shock factor 1 as a circadian transcription factor.Determinants of target gene specificity for ROR alpha 1: monomeric DNA binding by an orphan nuclear receptor.The monomer-binding orphan receptor Rev-Erb represses transcription as a dimer on a novel direct repeatRetinoic Acid-Related Orphan Receptors (RORs): Regulatory Functions in Immunity, Development, Circadian Rhythm, and Metabolism.Adopting new orphans into the family of metabolic regulatorsUsing a seed-network to query multiple large-scale gene expression datasets from the developing retina in order to identify and prioritize experimental targets.
P2860
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P2860
Cross-talk among ROR alpha 1 and the Rev-erb family of orphan nuclear receptors
description
1994 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
1994 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 1994
@ast
im September 1994 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 1994/09/01)
@sk
vědecký článek publikovaný v roce 1994
@cs
wetenschappelijk artikel (gepubliceerd op 1994/09/01)
@nl
наукова стаття, опублікована у вересні 1994
@uk
مقالة علمية (نشرت في سبتمبر 1994)
@ar
name
Cross-talk among ROR alpha 1 and the Rev-erb family of orphan nuclear receptors
@ast
Cross-talk among ROR alpha 1 and the Rev-erb family of orphan nuclear receptors
@en
Cross-talk among ROR alpha 1 and the Rev-erb family of orphan nuclear receptors
@nl
type
label
Cross-talk among ROR alpha 1 and the Rev-erb family of orphan nuclear receptors
@ast
Cross-talk among ROR alpha 1 and the Rev-erb family of orphan nuclear receptors
@en
Cross-talk among ROR alpha 1 and the Rev-erb family of orphan nuclear receptors
@nl
prefLabel
Cross-talk among ROR alpha 1 and the Rev-erb family of orphan nuclear receptors
@ast
Cross-talk among ROR alpha 1 and the Rev-erb family of orphan nuclear receptors
@en
Cross-talk among ROR alpha 1 and the Rev-erb family of orphan nuclear receptors
@nl
P2093
P921
P356
P1476
Cross-talk among ROR alpha 1 and the Rev-erb family of orphan nuclear receptors
@en
P2093
B. Blumberg
B. M. Forman
R. Henshaw
R. M. Evans
S. A. Kliewer
P304
P356
10.1210/MEND.8.9.7838158
P577
1994-09-01T00:00:00Z