staggerer phenotype in retinoid-related orphan receptor alpha-deficient mice. - Wikidata - wikimedia - TriplyDB

staggerer phenotype in retinoid-related orphan receptor alpha-deficient mice.

staggerer phenotype in retinoid-related orphan receptor alpha-deficient mice.

http://www.wikidata.org/entity/Q36014244

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Redundant function of REV-ERBalpha and beta and non-essential role for Bmal1 cycling in transcriptional regulation of intracellular circadian rhythms Transcriptional regulation of apolipoprotein C-III gene expression by the orphan nuclear receptor RORalpha The orphan nuclear receptor ROR alpha is a negative regulator of the inflammatory response Modulation of retinoic acid receptor-related orphan receptor alpha and gamma activity by 7-oxygenated sterol ligands Disruption of retinoid-related orphan receptor beta changes circadian behavior, causes retinal degeneration and leads to vacillans phenotype in mice Pathogenic mechanisms of a polyglutamine-mediated neurodegenerative disease, spinocerebellar ataxia type 1 In vitro and in vivo evidence for orphan nuclear receptor RORalpha function in bone metabolism Circadian clock regulation of skeletal muscle growth and repair The role of cerebellar circuitry alterations in the pathophysiology of autism spectrum disorders From genes to environment: using integrative genomics to build a "systems-level" understanding of autism spectrum disorders ROR nuclear receptors: structures, related diseases, and drug discovery T helper 17 lineage differentiation is programmed by orphan nuclear receptors ROR alpha and ROR gamma RORalpha coordinates reciprocal signaling in cerebellar development through sonic hedgehog and calcium-dependent pathways RORγ directly regulates the circadian expression of clock genes and downstream targets in vivo Mouse model reveals the role of RERE in cerebellar foliation and the migration and maturation of Purkinje cells NABP1, a novel RORgamma-regulated gene encoding a single-stranded nucleic-acid-binding protein Retinoic acid actions through mammalian nuclear receptors.Impairments in motor coordination without major changes in cerebellar plasticity in the Tc1 mouse model of Down syndrome Convergence of linkage, gene expression and association data demonstrates the influence of the RAR-related orphan receptor alpha (RORA) gene on neovascular AMD: a systems biology based approach Hairless is a nuclear receptor corepressor essential for skin function.The benzenesulfoamide T0901317 [N-(2,2,2-trifluoroethyl)-N-[4-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]phenyl]-benzenesulfonamide] is a novel retinoic acid receptor-related orphan receptor-alpha/gamma inverse agonist.RORα and ROR γ are expressed in human skin and serve as receptors for endogenously produced noncalcemic 20-hydroxy- and 20,23-dihydroxyvitamin D.Analysis of hairless corepressor mutants to characterize molecular cooperation with the vitamin D receptor in promoting the mammalian hair cycle.RORα binds to E2F1 to inhibit cell proliferation and regulate mammary gland branching morphogenesis Ligand regulation of retinoic acid receptor-related orphan receptors: implications for development of novel therapeutics Identification of Reverb(alpha) as a novel ROR(alpha) target gene.Transcriptional regulation of human Rev-erbalpha gene expression by the orphan nuclear receptor retinoic acid-related orphan receptor alpha.RORα suppresses breast tumor invasion by inducing SEMA3F expression Spermatogenesis and testis development are normal in mice lacking testicular orphan nuclear receptor 2 Phenotypic and genetic analysis of the cerebellar mutant tmgc26, a new ENU-induced ROR-alpha allele Novel mechanism of nuclear receptor corepressor interaction dictated by activation function 2 helix determinants.Action of RORs and their ligands in (patho)physiology.Regulation of the human hydroxysteroid sulfotransferase (SULT2A1) by RORα and RORγ and its potential relevance to human liver diseases.REV-ERB and ROR nuclear receptors as drug targets.Sp1 elements in SULT2B1b promoter and 5'-untranslated region of mRNA: Sp1/Sp2 induction and augmentation by histone deacetylase inhibition.Prospective study of common variants in the retinoic acid receptor-related orphan receptor α gene and risk of neovascular age-related macular degeneration.Mutant laboratory mice with abnormalities in hair follicle morphogenesis, cycling, and/or structure: annotated tables.Activation of orphan receptor-mediated transcription by Ca(2+)/calmodulin-dependent protein kinase IV.Creation of differentiation-specific genomic maps of human epidermis through laser capture microdissection Homozygous staggerer (sg/sg) mice display improved insulin sensitivity and enhanced glucose uptake in skeletal muscle

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staggerer phenotype in retinoid-related orphan receptor alpha-deficient mice.

http://www.wikidata.org/entity/Q36014244

description

1998 nî lūn-bûn

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1998年の論文

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1998年学术文章

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1998年学术文章

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1998年学术文章

@zh-hans

1998年学术文章

@zh-my

1998年学术文章

@zh-sg

1998年學術文章

@yue

1998年學術文章

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1998年學術文章

@zh-hant

name

staggerer phenotype in retinoid-related orphan receptor alpha-deficient mice.

@ast

staggerer phenotype in retinoid-related orphan receptor alpha-deficient mice.

@en

type

label

staggerer phenotype in retinoid-related orphan receptor alpha-deficient mice.

@ast

staggerer phenotype in retinoid-related orphan receptor alpha-deficient mice.

@en

prefLabel

staggerer phenotype in retinoid-related orphan receptor alpha-deficient mice.

@ast

staggerer phenotype in retinoid-related orphan receptor alpha-deficient mice.

@en

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Proceedings of the National Academy of Sciences of the United States of America

P1476

staggerer phenotype in retinoid-related orphan receptor alpha-deficient mice

@en

P2093

E André

http://www.w3.org/2001/XMLSchema#string

F Conquet

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F Crépel

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H Daniel

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M Becker-André

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M Steinmayr

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N Auclair

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N Delhaye-Bouchaud

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P2860

ROR gamma: the third member of ROR/RZR orphan receptor subfamily that is highly expressed in skeletal muscle

Isoform-specific amino-terminal domains dictate DNA-binding properties of ROR alpha, a novel family of orphan hormone nuclear receptors

RZRs, a new family of retinoid-related orphan receptors that function as both monomers and homodimers

The steroid and thyroid hormone receptor superfamily

Cross-talk among ROR alpha 1 and the Rev-erb family of orphan nuclear receptors

Targeted replacement of the homeobox gene Hox-3.1 by the Escherichia coli lacZ in mouse chimeric embryos.

Staggerer, a new mutation in the mouse affecting the cerebellum.

Identification of nuclear receptor mRNAs by RT-PCR amplification of conserved zinc-finger motif sequences.

Deficient cerebellar long-term depression and impaired motor learning in mGluR1 mutant mice.

Motor deficit and impairment of synaptic plasticity in mice lacking mGluR1.

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3960-3965

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10.1073/PNAS.95.7.3960

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7

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95

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Constantino Sotelo

Laure Rondi-Reig

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51314531

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9520475

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19945

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