Adipose-specific expression, phosphorylation of Ser794 in insulin receptor substrate-1, and activation in diabetic animals of salt-inducible kinase-2
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Phosphorylation of microtubule-associated protein tau by AMPK-related kinasesLKB1 is a master kinase that activates 13 kinases of the AMPK subfamily, including MARK/PAR-1RegPhos: a system to explore the protein kinase-substrate phosphorylation network in humansMolecular mechanisms of insulin resistance in humans and their potential links with mitochondrial dysfunctionC. elegans serine-threonine kinase KIN-29 modulates TGFbeta signaling and regulates body size formation.Regulation of insulin sensitivity by serine/threonine phosphorylation of insulin receptor substrate proteins IRS1 and IRS2SIK1 is part of a cell sodium-sensing network that regulates active sodium transport through a calcium-dependent processCaffeine modulates phosphorylation of insulin receptor substrate-1 and impairs insulin signal transduction in rat skeletal muscleIdentification of salt-inducible kinase 3 as a novel tumor antigen associated with tumorigenesis of ovarian cancer.Insulin and metabolic stress stimulate multisite serine/threonine phosphorylation of insulin receptor substrate 1 and inhibit tyrosine phosphorylation.Regulation of AMP-activated protein kinase by LKB1 and CaMKK in adipocytes.AMP-activated protein kinase inhibits IGF-I signaling and protein synthesis in vascular smooth muscle cells via stimulation of insulin receptor substrate 1 S794 and tuberous sclerosis 2 S1345 phosphorylation.Interaction between salt-inducible kinase 2 and protein phosphatase 2A regulates the activity of calcium/calmodulin-dependent protein kinase I and protein phosphatase methylesterase-1.Chemical proteomics-based analysis of off-target binding profiles for rosiglitazone and pioglitazone: clues for assessing potential for cardiotoxicity.The LKB1-salt-inducible kinase pathway functions as a key gluconeogenic suppressor in the liver.The AMPK-related kinase SIK2 is regulated by cAMP via phosphorylation at Ser358 in adipocytesRole of salt-inducible kinase 1 in the activation of MEF2-dependent transcription by BDNFα-TEA cooperates with MEK or mTOR inhibitors to induce apoptosis via targeting IRS/PI3K pathways.Improved insulin sensitivity by calorie restriction is associated with reduction of ERK and p70S6K activities in the liver of obese Zucker ratsA hormone-dependent module regulating energy balance.Lack of salt-inducible kinase 2 (SIK2) prevents the development of cardiac hypertrophy in response to chronic high-salt intake.Activation of AMPKα2 in adipocytes is essential for nicotine-induced insulin resistance in vivo.A potent inhibitor of SIK2, 3, 3', 7-trihydroxy-4'-methoxyflavon (4'-O-methylfisetin), promotes melanogenesis in B16F10 melanoma cells.KIN-29 SIK regulates chemoreceptor gene expression via an MEF2 transcription factor and a class II HDAC.Salt-inducible Kinase 3 Signaling Is Important for the Gluconeogenic Programs in Mouse Hepatocytes.Muscle-specific knock-out of NUAK family SNF1-like kinase 1 (NUAK1) prevents high fat diet-induced glucose intoleranceSalt-inducible kinase 2 and -3 are downregulated in adipose tissue from obese or insulin-resistant individuals: implications for insulin signalling and glucose uptake in human adipocytes.Phosphorylation of the insulin receptor by AMP-activated protein kinase (AMPK) promotes ligand-independent activation of the insulin signalling pathway in rodent muscleSkeletal muscle salt inducible kinase 1 promotes insulin resistance in obesity.AMPK and Exercise: Glucose Uptake and Insulin Sensitivity.Reversible acetylation regulates salt-inducible kinase (SIK2) and its function in autophagyPotential Role of the AMP-activated Protein Kinase in Regulation of Insulin Action.Activation of salt-inducible kinase 2 promotes the viability of peritoneal mesothelial cells exposed to stress of peritoneal dialysisPhosphorylation of IRS proteins, insulin action, and insulin resistance.Interaction between salt-inducible kinase 2 (SIK2) and p97/valosin-containing protein (VCP) regulates endoplasmic reticulum (ER)-associated protein degradation in mammalian cells.Insulin resistance due to phosphorylation of insulin receptor substrate-1 at serine 302.The diverse oncogenic and tumor suppressor roles of salt-inducible kinase (SIK) in cancer.Salt-inducible kinase 2 regulates mitotic progression and transcription in prostate cancerSIK2 regulates CRTCs, HDAC4 and glucose uptake in adipocytes.Inhibition of SIK2 and SIK3 during differentiation enhances the anti-inflammatory phenotype of macrophages
P2860
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P2860
Adipose-specific expression, phosphorylation of Ser794 in insulin receptor substrate-1, and activation in diabetic animals of salt-inducible kinase-2
description
2003 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի մայիսին հրատարակված գիտական հոդված
@hy
article publié dans la revue scientifique Journal of Biological Chemistry
@fr
artículu científicu espublizáu en 2003
@ast
im Mai 2003 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2003/05/16)
@sk
vědecký článek publikovaný v roce 2003
@cs
wetenschappelijk artikel (gepubliceerd op 2003/05/16)
@nl
наукова стаття, опублікована в травні 2003
@uk
name
Adipose-specific expression, p ...... als of salt-inducible kinase-2
@ast
Adipose-specific expression, p ...... als of salt-inducible kinase-2
@en
Adipose-specific expression, p ...... als of salt-inducible kinase-2
@nl
type
label
Adipose-specific expression, p ...... als of salt-inducible kinase-2
@ast
Adipose-specific expression, p ...... als of salt-inducible kinase-2
@en
Adipose-specific expression, p ...... als of salt-inducible kinase-2
@nl
prefLabel
Adipose-specific expression, p ...... als of salt-inducible kinase-2
@ast
Adipose-specific expression, p ...... als of salt-inducible kinase-2
@en
Adipose-specific expression, p ...... als of salt-inducible kinase-2
@nl
P2093
P2860
P921
P3181
P356
P1476
Adipose-specific expression, p ...... als of salt-inducible kinase-2
@en
P2093
Hiroshi Takemori
Hiroyasu Yamamoto
Masaaki Muraoka
Mitsuhiro Okamoto
Nanao Horike
Soji Kasayama
Tomoichiro Asano
Xiao Jian Sun
P2860
P304
18440–18447
P3181
P356
10.1074/JBC.M211770200
P407
P577
2003-05-16T00:00:00Z