The LKB1-salt-inducible kinase pathway functions as a key gluconeogenic suppressor in the liver. - Wikidata - wikimedia - TriplyDB

The LKB1-salt-inducible kinase pathway functions as a key gluconeogenic suppressor in the liver.

The LKB1-salt-inducible kinase pathway functions as a key gluconeogenic suppressor in the liver.

http://www.wikidata.org/entity/Q34086454

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Use of bedaquiline and delamanid in diabetes patients: clinical and pharmacological considerations The emerging role of AMPK in the regulation of breathing and oxygen supply The interplay between obesity and cancer: a fly view Salt-inducible Kinase 3 Signaling Is Important for the Gluconeogenic Programs in Mouse Hepatocytes.LKB1 and Notch Pathways Interact and Control Biliary Morphogenesis.Salt-inducible kinase 2 and -3 are downregulated in adipose tissue from obese or insulin-resistant individuals: implications for insulin signalling and glucose uptake in human adipocytes.Liver AMP-Activated Protein Kinase Is Unnecessary for Gluconeogenesis but Protects Energy State during Nutrient Deprivation.Salt-inducible kinases mediate nutrient-sensing to link dietary sugar and tumorigenesis in Drosophila.Skeletal muscle salt inducible kinase 1 promotes insulin resistance in obesity.Deletion of Lkb1 in Renal Tubular Epithelial Cells Leads to CKD by Altering Metabolism.Anti-Inflammatory Effects of Metformin Irrespective of Diabetes Status SIKs control osteocyte responses to parathyroid hormone SIK2 Restricts Autophagic Flux To Support Triple-Negative Breast Cancer Survival.Benzimidazole derivative small-molecule 991 enhances AMPK activity and glucose uptake induced by AICAR or contraction in skeletal muscle.Down-regulation of salt-inducible kinase 1 (SIK1) is mediated by RNF2 in hepatocarcinogenesis.The diverse oncogenic and tumor suppressor roles of salt-inducible kinase (SIK) in cancer.AMPK antagonizes hepatic glucagon-stimulated cyclic AMP signalling via phosphorylation-induced activation of cyclic nucleotide phosphodiesterase 4B.SIK2 regulates CRTCs, HDAC4 and glucose uptake in adipocytes.Deregulation of CRTCs in Aging and Age-Related Disease Risk.The mechanisms of action of metformin.Development of Chemical Probes for Investigation of Salt-Inducible Kinase Function in Vivo.Deletion of Lkb1 in adult mice results in body weight reduction and lethality.14-3-3 proteins mediate inhibitory effects of cAMP on salt-inducible kinases (SIKs).The tumor suppressor gene lkb1 is essential for glucose homeostasis during zebrafish early development.Salt-inducible kinase induces cytoplasmic histone deacetylase 4 to promote vascular calcification.The protein kinase SIK downregulates the polarity protein Par3.Post-translational regulation contributes to the loss of LKB1 expression through SIRT1 deacetylase in osteosarcomas.The energy sensing LKB1-AMPKα1 pathway regulates IGF1 secretion and consequent activation of the IGF1R-PKB pathway in primary hepatocytes.Structure of the complex of phosphorylated liver kinase B1 and 14-3-3ζ.LKB1, Salt-Inducible Kinases, and MEF2C Are Linked Dependencies in Acute Myeloid Leukemia.Drosophila as a Model to Study the Link between Metabolism and Cancer.Parathyroid Hormone Signaling in Osteocytes Identifying Inhibitors of Inflammation: A Novel High-Throughput MALDI-TOF Screening Assay for Salt-Inducible Kinases (SIKs)Analysing the Expression of Eight Clock Genes in Five Tissues From Fasting and Fed Sows Upregulation of liver kinase B1 predicts poor prognosis in hepatocellular carcinoma

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The LKB1-salt-inducible kinase pathway functions as a key gluconeogenic suppressor in the liver.

http://www.wikidata.org/entity/Q34086454

description

2014 nî lūn-bûn

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2014 թուականի Օգոստոսին հրատարակուած գիտական յօդուած

@hyw

2014 թվականի օգոստոսին հրատարակված գիտական հոդված

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2014年の論文

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2014年学术文章

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2014年学术文章

@zh-cn

2014年学术文章

@zh-hans

2014年学术文章

@zh-my

2014年学术文章

@zh-sg

2014年學術文章

@yue

name

The LKB1-salt-inducible kinase ...... genic suppressor in the liver.

@ast

The LKB1-salt-inducible kinase ...... genic suppressor in the liver.

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The LKB1-salt-inducible kinase ...... genic suppressor in the liver.

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type

label

The LKB1-salt-inducible kinase ...... genic suppressor in the liver.

@ast

The LKB1-salt-inducible kinase ...... genic suppressor in the liver.

@en

The LKB1-salt-inducible kinase ...... genic suppressor in the liver.

@nl

prefLabel

The LKB1-salt-inducible kinase ...... genic suppressor in the liver.

@ast

The LKB1-salt-inducible kinase ...... genic suppressor in the liver.

@en

The LKB1-salt-inducible kinase ...... genic suppressor in the liver.

@nl

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Nature Communications

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The LKB1-salt-inducible kinase ...... genic suppressor in the liver.

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Allison Marion

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David G Campbell

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Emilie Tournier

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Kei Sakamoto

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Klaus H Kaestner

http://www.w3.org/2001/XMLSchema#string

Mark Peggie

http://www.w3.org/2001/XMLSchema#string

Min Wan

http://www.w3.org/2001/XMLSchema#string

Nadia Boudaba

http://www.w3.org/2001/XMLSchema#string

Nathanael S Gray

http://www.w3.org/2001/XMLSchema#string

Olga Göransson

http://www.w3.org/2001/XMLSchema#string

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Role of AMP-activated protein kinase in mechanism of metformin action

Biguanides suppress hepatic glucagon signalling by decreasing production of cyclic AMP

Molecular mechanism of action of metformin: old or new insights?

14-3-3 cooperates with LKB1 to regulate the activity and localization of QSK and SIK

Phosphorylation of CRTC3 by the salt-inducible kinases controls the interconversion of classically activated and regulatory macrophages

LKB1 is a master kinase that activates 13 kinases of the AMPK subfamily, including MARK/PAR-1

The CREB coactivator TORC2 functions as a calcium- and cAMP-sensitive coincidence detector

Adipose-specific expression, phosphorylation of Ser794 in insulin receptor substrate-1, and activation in diabetic animals of salt-inducible kinase-2

The kinase LKB1 mediates glucose homeostasis in liver and therapeutic effects of metformin

The CREB coactivator TORC2 is a key regulator of fasting glucose metabolism

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10.1038/NCOMMS5535

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5

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Calum Sutherland

Morris J. Birnbaum

Kashyap A Patel

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2014-08-04T00:00:00Z

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264462899

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