Polycystin-dependent fluid flow sensing targets histone deacetylase 5 to prevent the development of renal cysts
about
Polycystin-1 regulates the stability and ubiquitination of transcription factor Jade-1Experimental therapies and ongoing clinical trials to slow down progression of ADPKDThe role of the cilium in normal and abnormal cell cycles: emphasis on renal cystic pathologiesRole of PKD2 in rheotaxis in DictyosteliumEpigenetics of Renal Development and DiseaseHDAC6 regulates epidermal growth factor receptor (EGFR) endocytic trafficking and degradation in renal epithelial cells.Tolvaptan inhibits ERK-dependent cell proliferation, Cl⁻ secretion, and in vitro cyst growth of human ADPKD cells stimulated by vasopressinTreatment of chronic kidney diseases with histone deacetylase inhibitors.Mice deficient in MIM expression are predisposed to lymphomagenesis.Inhibition of histone deacetylases targets the transcription regulator Id2 to attenuate cystic epithelial cell proliferation.Epigenetics and autosomal dominant polycystic kidney disease.Ablation of the Stimulatory G Protein α-Subunit in Renal Proximal Tubules Leads to Parathyroid Hormone-Resistance With Increased Renal Cyp24a1 mRNA Abundance and Reduced Serum 1,25-Dihydroxyvitamin D.Dimerization is necessary for MIM-mediated membrane deformation and endocytosisProximal tubule-dominant transfer of AT(1a) receptors induces blood pressure responses to intracellular angiotensin II in AT(1a) receptor-deficient mice.Little fish, big catch: zebrafish as a model for kidney diseaseTechniques and Approaches to Genetic Analyses in Nephrological Disorders.HDAC inhibitors in kidney development and disease.Gene regulation in the vascular endothelium: why epigenetics is important for the kidney.Targeting of receptor for advanced glycation end products suppresses cyst growth in polycystic kidney disease.Inhibition of Comt with tolcapone slows progression of polycystic kidney disease in the more severely affected PKD/Mhm (cy/+) substrain of the Hannover Sprague-Dawley rat.Polycystic kidney disease: pathogenesis and potential therapies.Molecular and cellular pathogenesis of autosomal dominant polycystic kidney disease.Histone deacetylases in kidney development: implications for disease and therapy.New treatments for autosomal dominant polycystic kidney diseaseSystems biology of the functional and dysfunctional endothelium.Expanding horizons: ciliary proteins reach beyond cilia.Developmental signaling: does it bridge the gap between cilia dysfunction and renal cystogenesis?Epigenetic Regulation in Cystogenesis.Deletion of ADP Ribosylation Factor-Like GTPase 13B Leads to Kidney Cysts.MIM regulates the trafficking of bone marrow cells via modulating surface expression of CXCR4.Therapeutic effects of histone deacetylase inhibitors on kidney disease.Missing-in-metastasis protein downregulates CXCR4 by promoting ubiquitylation and interaction with small Rab GTPases.Mtss1 promotes maturation and maintenance of cerebellar neurons via splice variant-specific effects.Fluid shear stress induces renal epithelial gene expression through polycystin-2-dependent trafficking of extracellular regulated kinase.Mechanism-based therapeutics for autosomal dominant polycystic kidney disease: recent progress and future prospects.Nitric oxide synthase and polycystic kidney disease.Activation of Calcium-Sensing Receptor increases intracellular calcium and decreases cAMP and mTOR in PKD1 deficient cells.
P2860
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P2860
Polycystin-dependent fluid flow sensing targets histone deacetylase 5 to prevent the development of renal cysts
description
2010 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2010
@ast
im April 2010 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2010/04/01)
@sk
vědecký článek publikovaný v roce 2010
@cs
wetenschappelijk artikel (gepubliceerd op 2010/04/01)
@nl
наукова стаття, опублікована у квітні 2010
@uk
مقالة علمية (نشرت في أبريل 2010)
@ar
name
Polycystin-dependent fluid flo ...... the development of renal cysts
@ast
Polycystin-dependent fluid flo ...... the development of renal cysts
@en
Polycystin-dependent fluid flo ...... the development of renal cysts
@nl
type
label
Polycystin-dependent fluid flo ...... the development of renal cysts
@ast
Polycystin-dependent fluid flo ...... the development of renal cysts
@en
Polycystin-dependent fluid flo ...... the development of renal cysts
@nl
prefLabel
Polycystin-dependent fluid flo ...... the development of renal cysts
@ast
Polycystin-dependent fluid flo ...... the development of renal cysts
@en
Polycystin-dependent fluid flo ...... the development of renal cysts
@nl
P2093
P2860
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P356
P1433
P1476
Polycystin-dependent fluid flo ...... the development of renal cysts
@en
P2093
Chris Seidel
Darren P. Wallace
Teri Johnson
Xiaogang Li
P2860
P304
P356
10.1242/DEV.049437
P407
P577
2010-04-01T00:00:00Z