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A functional screen to identify novel effectors of hematopoietic stem cell activity

A functional screen to identify novel effectors of hematopoietic stem cell activity

http://www.wikidata.org/entity/Q28513837

about

MicroRNAs enriched in hematopoietic stem cells differentially regulate long-term hematopoietic output UBAP2L is a novel BMI1-interacting protein essential for hematopoietic stem cell activity Maintaining tissue homeostasis: dynamic control of somatic stem cell activity High-mobility group box 1: an amplifier of stem and progenitor cell activity after stroke Increased learning and brain long-term potentiation in aged mice lacking DNA polymerase μ Tcf7 is an important regulator of the switch of self-renewal and differentiation in a multipotential hematopoietic cell line Hemp, an mbt domain-containing protein, plays essential roles in hematopoietic stem cell function and skeletal formation Sox4 links tumor suppression to accelerated aging in mice by modulating stem cell activation Sox4 is a key oncogenic target in C/EBPα mutant acute myeloid leukemia Identification of sexually dimorphic genes in the neonatal mouse cortex and hippocampus Ectopic expression of HOXC6 blocks myeloid differentiation and predisposes to malignant transformation.Wnt4 enhances murine hematopoietic progenitor cell expansion through a planar cell polarity-like pathway Aging-like phenotype and defective lineage specification in SIRT1-deleted hematopoietic stem and progenitor cells Downstream targets of HOXB4 in a cell line model of primitive hematopoietic progenitor cells Prdm16 promotes stem cell maintenance in multiple tissues, partly by regulating oxidative stress The HOXB4 homeoprotein promotes the ex vivo enrichment of functional human embryonic stem cell-derived NK cells A novel molecular mechanism involved in multiple myeloma development revealed by targeting MafB to haematopoietic progenitors.Stem cells and the niche: a dynamic duo.An in vivo functional screen uncovers miR-150-mediated regulation of hematopoietic injury response.Pathogenic microRNA's in myeloid malignancies.EGF signaling regulates the proliferation of intestinal stem cells in Drosophila HMGB1 in health and disease.SCL, LMO1 and Notch1 reprogram thymocytes into self-renewing cells Cord blood-derived hematopoietic stem/progenitor cells: current challenges in engraftment, infection, and ex vivo expansion.Prdm16 is a physiologic regulator of hematopoietic stem cells.SOX4 interacts with EZH2 and HDAC3 to suppress microRNA-31 in invasive esophageal cancer cells A pooled shRNA screen for regulators of primary mammary stem and progenitor cells identifies roles for Asap1 and Prox1.Ontogeny stage-independent and high-level clonal expansion in vitro of mouse hematopoietic stem cells stimulated by an engineered NUP98-HOX fusion transcription factor Integrin-αvβ3 regulates thrombopoietin-mediated maintenance of hematopoietic stem cells.Genome-wide analysis of target genes regulated by HoxB4 in hematopoietic stem and progenitor cells developing from embryonic stem cells.Myeloid translocation gene 16 is required for maintenance of haematopoietic stem cell quiescence.A role for GPx3 in activity of normal and leukemia stem cells A New Triggering Receptor Expressed on Myeloid Cells (TREM) Family Member, TLT-6, is Involved in Activation and Proliferation of Macrophages A Mouse Model of Targeted Musashi1 Expression in Whole Intestinal Epithelium Suggests Regulatory Roles in Cell Cycle and Stemness Functional screen identifies regulators of murine hematopoietic stem cell repopulation An MLL-dependent network sustains hematopoiesis.Highly Efficient Genome Editing of Murine and Human Hematopoietic Progenitor Cells by CRISPR/Cas9.Posttranslational regulation of self-renewal capacity: insights from proteome and phosphoproteome analyses of stem cell leukemia.RNAi screen identifies Jarid1b as a major regulator of mouse HSC activity.PRDM proteins: important players in differentiation and disease.

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P2860

A functional screen to identify novel effectors of hematopoietic stem cell activity

http://www.wikidata.org/entity/Q28513837

description

2009 թուականի Ապրիլին հրատարակուած գիտական յօդուած

@hyw

2009 թվականի ապրիլին հրատարակված գիտական հոդված

@hy

artículu científicu espublizáu en 2009

@ast

im April 2009 veröffentlichter wissenschaftlicher Artikel

@de

scientific journal article

@en

vedecký článok (publikovaný 2009/04/17)

@sk

vědecký článek publikovaný v roce 2009

@cs

wetenschappelijk artikel (gepubliceerd op 2009/04/17)

@nl

наукова стаття, опублікована у квітні 2009

@uk

مقالة علمية (نشرت في 17-4-2009)

@ar

name

A functional screen to identify novel effectors of hematopoietic stem cell activity

@ast

A functional screen to identify novel effectors of hematopoietic stem cell activity

@en

A functional screen to identify novel effectors of hematopoietic stem cell activity

@nl

type

label

A functional screen to identify novel effectors of hematopoietic stem cell activity

@ast

A functional screen to identify novel effectors of hematopoietic stem cell activity

@en

A functional screen to identify novel effectors of hematopoietic stem cell activity

@nl

prefLabel

A functional screen to identify novel effectors of hematopoietic stem cell activity

@ast

A functional screen to identify novel effectors of hematopoietic stem cell activity

@en

A functional screen to identify novel effectors of hematopoietic stem cell activity

@nl

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J.CELL.2009.03.026

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A functional screen to identify novel effectors of hematopoietic stem cell activity

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Amélie Faubert

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Eric Deneault

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Guy Sauvageau

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Jalila Chagraoui

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Jean-Philippe Laverdure

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Martin Sauvageau

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Mélanie Fréchette

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Nadine Mayotte

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Sonia Cellot

http://www.w3.org/2001/XMLSchema#string

Stephen B Ting

http://www.w3.org/2001/XMLSchema#string

P2860

Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors

Stem cells, the molecular circuitry of pluripotency and nuclear reprogramming

SLAM family receptors distinguish hematopoietic stem and progenitor cells and reveal endothelial niches for stem cells

Sustained in vitro trigger of self-renewal divisions in Hoxb4hiPbx1(10) hematopoietic stem cells.

ABC transporter activities of murine hematopoietic stem cells vary according to their developmental and activation status.

Genome-scale loss-of-function screening with a lentiviral RNAi library.

Quantitative assay for totipotent reconstituting hematopoietic stem cells by a competitive repopulation strategy

Overexpression of the myeloid leukemia-associated Hoxa9 gene in bone marrow cells induces stem cell expansion.

Hematopoietic stem cells proliferate until after birth and show a reversible phase-specific engraftment defect.

Genetic programs regulating HSC specification, maintenance and expansion.

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369-379

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10.1016/J.CELL.2009.03.026

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