about
Revealing Atomic-Level Mechanisms of Protein Allostery with Molecular Dynamics SimulationsPrinciples and Overview of Sampling Methods for Modeling Macromolecular Structure and DynamicsSmall Molecule Targeting of Protein-Protein Interactions through Allosteric Modulation of DynamicsPrinciples of allosteric interactions in cell signalingStructure-Based Statistical Mechanical Model Accounts for the Causality and Energetics of Allosteric CommunicationRigid Residue Scan Simulations Systematically Reveal Residue Entropic Roles in Protein AllosteryAllostery: An Overview of Its History, Concepts, Methods, and ApplicationsNMR Characterization of Information Flow and Allosteric Communities in the MAP Kinase p38γEntropy Transfer between Residue Pairs and Allostery in Proteins: Quantifying Allosteric Communication in UbiquitinIntegrating atomistic molecular dynamics simulations, experiments, and network analysis to study protein dynamics: strength in unity.Mutations in Antibody Fragments Modulate Allosteric Response Via Hydrogen-Bond Network Fluctuations.DNA-binding protects p53 from interactions with cofactors involved in transcription-independent functions.Vibrational resonance, allostery, and activation in rhodopsin-like G protein-coupled receptors.Evolutionary Covariance Combined with Molecular Dynamics Predicts a Framework for Allostery in the MutS DNA Mismatch Repair Protein.Dynamic, structural and thermodynamic basis of insulin-like growth factor 1 kinase allostery mediated by activation loop phosphorylation.Structure-based dynamic arrays in regulatory domains of sodium-calcium exchanger (NCX) isoforms.High-Dimensional Mutant and Modular Thermodynamic Cycles, Molecular Switching, and Free Energy Transduction.Possible mechanism and clinical potentials of allostery.Prepaying the entropic cost for allosteric regulation in KIXThe structural basis of ATP as an allosteric modulatorSubstantial non-electrostatic forces are needed to induce allosteric disruption of thrombin's active site through exosite 2.The structural basis for cancer treatment decisions.Determinants of endogenous ligand specificity divergence among metabotropic glutamate receptorsRational Coupled Dynamics Network Manipulation Rescues Disease-Relevant Mutant Cystic Fibrosis Transmembrane Conductance Regulator.Dual allosteric activation mechanisms in monomeric human glucokinase.Coevolved Mutations Reveal Distinct Architectures for Two Core Proteins in the Bacterial Flagellar MotorTandem Domains with Tuned Interactions Are a Powerful Biological Design Principle.Dancing through Life: Molecular Dynamics Simulations and Network-Centric Modeling of Allosteric Mechanisms in Hsp70 and Hsp110 Chaperone Proteins.The Phylogenetic Signature Underlying ATP Synthase c-Ring Compliance.Mapping the Dynamics Landscape of Conformational Transitions in Enzyme: The Adenylate Kinase Case.Oncogenic mutations weaken the interactions that stabilize the p110α-p85α heterodimer in phosphatidylinositol 3-kinase α.The Role of Allostery in the Termination of Second Messenger Signaling.Kinetic Cooperativity in Human Pancreatic Glucokinase Originates from Millisecond Dynamics of the Small Domain.Computational Analysis of Residue Interaction Networks and Coevolutionary Relationships in the Hsp70 Chaperones: A Community-Hopping Model of Allosteric Regulation and CommunicationHigh Affinity vs. Native Fibronectin in the Modulation of αvβ3 Integrin Conformational Dynamics: Insights from Computational Analyses and Implications for Molecular DesignAIM for Allostery: Using the Ising Model to Understand Information Processing and Transmission in Allosteric Biomolecular Systems.GTP Binding and Oncogenic Mutations May Attenuate Hypervariable Region (HVR)-Catalytic Domain Interactions in Small GTPase K-Ras4B, Exposing the Effector Binding Site.Mechanistic Models Fit to Variable Temperature Calorimetric Data Provide Insights into Cooperativity.ASD v3.0: unraveling allosteric regulation with structural mechanisms and biological networks.An allosteric role for receptor activity-modifying proteins in defining GPCR pharmacology.
P2860
Q26747130-EB034A92-83B5-4733-9791-278FE9FFB44DQ26749162-8E5F5D3A-1268-4985-9C8D-13E2C77E079AQ26785992-D3B90BD1-83EA-47CB-B963-4BEAD231E45BQ26996431-2EB9D032-CEF1-4920-96AE-F2FFAA9F6371Q28550501-7C648834-30FF-4780-B223-DB465D8FCB3FQ28551601-DF556956-7681-4927-82E4-18406ED6BBABQ28552596-B7AA3DF7-C681-45D5-BBFD-ED59237CAF53Q28828493-948E3FFC-6C4D-45BF-BCF0-7A6649FCD2BEQ29248852-4E1CEF05-30DD-4C22-AC6D-80F132B3D34CQ30375668-9624F5C2-4D15-409D-BA51-DA636F0E8490Q30387960-6364C54F-53F4-44D6-BC9C-A8A6B43D4886Q30392650-9A6DD82D-1CD5-4651-9CD7-D2FD5C5EE5B7Q30395265-C320BB61-9553-4505-AC53-B02DA86CBCBBQ30841579-4CA0D52C-5AD1-4ED0-9BE8-871BB447BA07Q33640181-0A092E6D-2AA6-46EC-B105-6157FCE6253DQ33681272-B7AD3269-BC13-462F-81F6-225F4AB94382Q33802544-5F381408-51B8-4ABB-A63E-9AB46D3FEC97Q33880934-BC7EF641-A841-4A1E-98CB-D36C6434F561Q34082751-923EA77C-AE4F-4120-8B98-4176B2E1BDAEQ34165655-27479B9B-3293-4142-B0CF-96DA017B4BEDQ34264585-6FE2DBB0-B90D-49CB-9061-25725F465FECQ34365654-37A6CBF8-B073-4B4B-B9B6-BE7F41DF7AD2Q35048949-5FF87D12-8CC5-4AEB-B189-877A4987D05AQ35073390-11615BDB-950F-4C1A-8D11-D7A16F9D2DA2Q35748383-40995354-7538-4282-A1AF-9A459B5F24A1Q35839668-DACD09FA-A39F-47CA-BB52-53F0E709CFADQ35855522-E4DFA21B-9555-45AA-8C7D-3DADD5A5DF4AQ35855961-111C1BC4-1677-407D-893C-888D24E6D73EQ36043811-D423CE3F-5D67-40D3-8807-99DAF46D30EDQ36067046-1FB042E6-50D6-4AE7-AB16-8115960B9E43Q36070390-BEE5EDEF-C801-44E2-AC1B-56CCB3A2CB0EQ36076194-0F2A19F7-5DFF-449C-9FCB-C566F5B96F93Q36104359-0EF79F51-97BF-4153-A2D2-E5E7AFE396C4Q36251118-203B98D9-E204-42FD-8F64-3BCF05B7EA96Q36257638-7F7B7B4E-8001-4504-889B-3648546CB75BQ36299381-975413B3-FC92-46A0-8125-C13776EAD2E5Q36323471-CAC88D52-4B4C-4C82-9EF7-6A9AC71707D8Q36344658-1FFF0700-408B-4EC3-98E4-0DB2A8469D52Q36435052-CD3C1C89-3200-492E-9890-8913FB1D7079Q36907408-BD27BEDB-43A6-4AA2-B8F1-6C23B69373C7
P2860
description
2014 nî lūn-bûn
@nan
2014 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2014 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2014年の論文
@ja
2014年論文
@yue
2014年論文
@zh-hant
2014年論文
@zh-hk
2014年論文
@zh-mo
2014年論文
@zh-tw
2014年论文
@wuu
name
A unified view of "how allostery works"
@ast
A unified view of "how allostery works"
@en
A unified view of "how allostery works"
@nl
type
label
A unified view of "how allostery works"
@ast
A unified view of "how allostery works"
@en
A unified view of "how allostery works"
@nl
prefLabel
A unified view of "how allostery works"
@ast
A unified view of "how allostery works"
@en
A unified view of "how allostery works"
@nl
P2860
P3181
P1476
A unified view of "how allostery works"
@en
P2093
Chung-Jung Tsai
P2860
P304
P3181
P356
10.1371/JOURNAL.PCBI.1003394
P407
P577
2014-02-01T00:00:00Z