Isoforms of kalirin, a neuronal Dbl family member, generated through use of different 5'- and 3'-ends along with an internal translational initiation site
about
The Guanine nucleotide exchange factor kalirin-7 is a novel synphilin-1 interacting protein and modifies synphilin-1 aggregate transport and formationCritical role for Kalirin in nerve growth factor signaling through TrkA.Mechanisms of synapse and dendrite maintenance and their disruption in psychiatric and neurodegenerative disordersKalirin-7 is required for synaptic structure and functionKalirin regulates cortical spine morphogenesis and disease-related behavioral phenotypesThe trio guanine nucleotide exchange factor is a RhoA target. Binding of RhoA to the trio immunoglobulin-like domainKalrn plays key roles within and outside of the nervous systemA role for Kalirin-7 in nociceptive sensitization via activity-dependent modulation of spinal synapsesRegulation of Kalirin by Cdk5Elimination of Kalrn expression in POMC cells reduces anxiety-like behavior and contextual fear learning.Hippocampal phenotypes in kalirin-deficient mice.Arf6 recruits the Rac GEF Kalirin to the plasma membrane facilitating Rac activation.Kalirin12 interacts with dynamin.Kalirin loss results in cortical morphological alterationsKalrn promoter usage and isoform expression respond to chronic cocaine exposureBehavioral and morphological responses to cocaine require kalirin7.Kalirin-7 is necessary for normal NMDA receptor-dependent synaptic plasticityA sequence variant in human KALRN impairs protein function and coincides with reduced cortical thickness.High-throughput single-cell manipulation in brain tissue.Genetic analysis of polymorphisms in the kalirin gene for association with age-at-onset in European Huntington disease patients.Identification of novel neuronal isoforms of the Rho-GEF Trio.Dendritic spine dynamics--a key role for kalirin-7.Solo/Trio8, a membrane-associated short isoform of Trio, modulates endosome dynamics and neurite elongation.Control of synapse development and plasticity by Rho GTPase regulatory proteins.Skeletal muscle deformity and neuronal disorder in Trio exchange factor-deficient mouse embryos.Increased expression of Kalirin-9 in the auditory cortex of schizophrenia subjects: its role in dendritic pathologyResequencing and association analysis of the KALRN and EPHB1 genes and their contribution to schizophrenia susceptibility.β-Amyloid 42/40 ratio and kalirin expression in Alzheimer disease with psychosisKalirin: a dual Rho guanine nucleotide exchange factor that is so much more than the sum of its many parts.Kalirin-9 and Kalirin-12 Play Essential Roles in Dendritic Outgrowth and Branching.Kalirin/Trio Rho guanine nucleotide exchange factors regulate a novel step in secretory granule maturationA role for kalirin in the response of rat medium spiny neurons to cocaine.Kalirin-7 is an essential component of both shaft and spine excitatory synapses in hippocampal interneurons.Synaptic plasticity, a symphony in GEF.Rho-guanine nucleotide exchange factors during development: Force is nothing without control.Deconstructing signal transduction pathways that regulate the actin cytoskeleton in dendritic spines.Kalirin, a key player in synapse formation, is implicated in human diseases.Reversing synapse loss in Alzheimer's disease: Rho-guanosine triphosphatases and insights from other brain disorders.A Novel Long Non-coding RNA, durga Modulates Dendrite Density and Expression of kalirin in ZebrafishAge-dependent increase in Kalirin-9 and Kalirin-12 transcripts in human orbitofrontal cortex.
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P2860
Isoforms of kalirin, a neuronal Dbl family member, generated through use of different 5'- and 3'-ends along with an internal translational initiation site
description
2000 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2000 թվականի հունիսին հրատարակված գիտական հոդված
@hy
article publié dans la revue scientifique Journal of Biological Chemistry
@fr
artículu científicu espublizáu en 2000
@ast
im Juni 2000 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2000/06/23)
@sk
vědecký článek publikovaný v roce 2000
@cs
wetenschappelijk artikel (gepubliceerd op 2000/06/23)
@nl
наукова стаття, опублікована в червні 2000
@uk
name
Isoforms of kalirin, a neurona ...... translational initiation site
@ast
Isoforms of kalirin, a neurona ...... translational initiation site
@en
Isoforms of kalirin, a neurona ...... translational initiation site
@nl
type
label
Isoforms of kalirin, a neurona ...... translational initiation site
@ast
Isoforms of kalirin, a neurona ...... translational initiation site
@en
Isoforms of kalirin, a neurona ...... translational initiation site
@nl
prefLabel
Isoforms of kalirin, a neurona ...... translational initiation site
@ast
Isoforms of kalirin, a neurona ...... translational initiation site
@en
Isoforms of kalirin, a neurona ...... translational initiation site
@nl
P2093
P2860
P356
P1476
Isoforms of kalirin, a neurona ...... translational initiation site
@en
P2093
B. A. Eipper
R. C. Johnson
R. E. Mains
P2860
P304
19324–19333
P356
10.1074/JBC.M000676200
P407
P577
2000-06-23T00:00:00Z