Activation of MAP kinase kinase (MEK) and Ras by cholecystokinin in rat pancreatic acini
about
Interleukin-6 is required for pancreatic cancer progression by promoting MAPK signaling activation and oxidative stress resistanceBeta-catenin blocks Kras-dependent reprogramming of acini into pancreatic cancer precursor lesions in mice.MAPK signaling is required for dedifferentiation of acinar cells and development of pancreatic intraepithelial neoplasia in mice.Disruption of the murine protein kinase Cbeta gene promotes gallstone formation and alters biliary lipid and hepatic cholesterol metabolismEffect of mitogen-activated protein kinases on chemokine synthesis induced by substance P in mouse pancreatic acinar cells.PKCθ activation in pancreatic acinar cells by gastrointestinal hormones/neurotransmitters and growth factors is needed for stimulation of numerous important cellular signaling cascades.An NF-κB pathway-mediated positive feedback loop amplifies Ras activity to pathological levels in mice.Characterization of the antiproliferative signal mediated by the somatostatin receptor subtype sst5.Overexpression of Rab3D enhances regulated amylase secretion from pancreatic acini of transgenic mice.Ras activity in acinar cells links chronic pancreatitis and pancreatic cancer.Molecular biology of pancreatic ductal adenocarcinoma progression: aberrant activation of developmental pathways.Ras activity levels control the development of pancreatic diseases.Bombesin stimulates cholecystokinin secretion through mitogen-activated protein-kinase-dependent and -independent mechanisms in the enteroendocrine STC-1 cell line.Cholecystokinin octapeptide inhibits Ca2+-dependent amylase secretion from permeabilized pancreatic acini by blocking the MgATP-dependent priming of exocytosis.CD4+ T lymphocyte ablation prevents pancreatic carcinogenesis in mice.Ras activation in response to phorbol ester proceeds independently of the EGFR via an unconventional nucleotide-exchange factor system in COS-7 cells.Nicotine as a mitogenic stimulus for pancreatic acinar cell proliferation.Cholecystokinin-stimulated tyrosine phosphorylation of p125FAK and paxillin is mediated by phospholipase C-dependent and -independent mechanisms and requires the integrity of the actin cytoskeleton and participation of p21rho.
P2860
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P2860
Activation of MAP kinase kinase (MEK) and Ras by cholecystokinin in rat pancreatic acini
description
1995 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
1995 թվականի հունիսին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 1995
@ast
im Juni 1995 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 1995/06/01)
@sk
vědecký článek publikovaný v roce 1995
@cs
wetenschappelijk artikel (gepubliceerd op 1995/06/01)
@nl
наукова стаття, опублікована в червні 1995
@uk
مقالة علمية (نشرت في يونيو 1995)
@ar
name
Activation of MAP kinase kinase (MEK) and Ras by cholecystokinin in rat pancreatic acini
@ast
Activation of MAP kinase kinase (MEK) and Ras by cholecystokinin in rat pancreatic acini
@en
Activation of MAP kinase kinase (MEK) and Ras by cholecystokinin in rat pancreatic acini
@nl
type
label
Activation of MAP kinase kinase (MEK) and Ras by cholecystokinin in rat pancreatic acini
@ast
Activation of MAP kinase kinase (MEK) and Ras by cholecystokinin in rat pancreatic acini
@en
Activation of MAP kinase kinase (MEK) and Ras by cholecystokinin in rat pancreatic acini
@nl
prefLabel
Activation of MAP kinase kinase (MEK) and Ras by cholecystokinin in rat pancreatic acini
@ast
Activation of MAP kinase kinase (MEK) and Ras by cholecystokinin in rat pancreatic acini
@en
Activation of MAP kinase kinase (MEK) and Ras by cholecystokinin in rat pancreatic acini
@nl
P2093
P1476
Activation of MAP kinase kinase (MEK) and Ras by cholecystokinin in rat pancreatic acini
@en
P2093
C. F. Zheng
J. A. Williams
K. L. Guan
R. D. Duan
P304
G1060–1065
P356
10.1152/AJPGI.1995.268.6.G1060
P407
P433
P577
1995-06-01T00:00:00Z