Reconstitution and characterization of a nicotinic acid adenine dinucleotide phosphate (NAADP)-sensitive Ca2+ release channel from liver lysosomes of rats
about
Essential requirement for two-pore channel 1 in NAADP-mediated calcium signalingTPC: the NAADP discovery channel?Membrane potential regulates nicotinic acid adenine dinucleotide phosphate (NAADP) dependence of the pH- and Ca2+-sensitive organellar two-pore channel TPC1Linking NAADP to ion channel activity: a unifying hypothesisAn ancestral deuterostome family of two-pore channels mediates nicotinic acid adenine dinucleotide phosphate-dependent calcium release from acidic organellesIsolated ocular disease is associated with decreased mucolipin-1 channel conductanceBidirectional Ca²⁺ signaling occurs between the endoplasmic reticulum and acidic organellesTwo-pore channels (TPCs): current controversiesIn vivo and ex vivo evaluation of L-type calcium channel blockers on acid beta-glucosidase in Gaucher disease mouse modelsReconstitution of lysosomal NAADP-TRP-ML1 signaling pathway and its function in TRP-ML1(-/-) cells.High resolution structural evidence suggests the Sarcoplasmic Reticulum forms microdomains with Acidic Stores (lysosomes) in the heartActivating mutations of the TRPML1 channel revealed by proline-scanning mutagenesis.Mucolipins: Intracellular TRPML1-3 channelsTPCs: Endolysosomal channels for Ca2+ mobilization from acidic organelles triggered by NAADPLysosome-dependent Ca(2+) release response to Fas activation in coronary arterial myocytes through NAADP: evidence from CD38 gene knockouts.Two-pore channels for integrative Ca signaling.TRP channels of intracellular membranesCalcium- and polyphosphate-containing acidic granules of sea urchin eggs are similar to acidocalcisomes, but are not the targets for NAADPTwo-pore channels: Regulation by NAADP and customized roles in triggering calcium signalsNAADP receptors.The Ca(2+) channel TRPML3 regulates membrane trafficking and autophagyFunction and dysfunction of two-pore channels.Two pore channel 2 differentially modulates neural differentiation of mouse embryonic stem cells.Transient receptor potential mucolipin 1 (TRPML1) and two-pore channels are functionally independent organellar ion channelsRole of TRP channels in the regulation of the endosomal pathway.Nicotinic acid adenine dinucleotide phosphate (NAADP) activates global and heterogeneous local Ca2+ signals from NAADP- and ryanodine receptor-gated Ca2+ stores in pulmonary arterial myocytesNicotinic acid adenine dinucleotide phosphate (NAADP)-mediated calcium signaling and arrhythmias in the heart evoked by β-adrenergic stimulation.Mitochondrial Ca2+ homeostasis in lysosomal storage diseases.TRP-ML1 functions as a lysosomal NAADP-sensitive Ca2+ release channel in coronary arterial myocytesTRPMLs: in sickness and in health.NAADP-mediated Ca2+ signaling via type 1 ryanodine receptor in T cells revealed by a synthetic NAADP antagonistCompartmentalized signalling: Ca2+ compartments, microdomains and the many facets of Ca2+ signalling.The acid test: the discovery of two-pore channels (TPCs) as NAADP-gated endolysosomal Ca(2+) release channels.Simvastatin promotes NPC1-mediated free cholesterol efflux from lysosomes through CYP7A1/LXRα signalling pathway in oxLDL-loaded macrophages.In with the TRP channels: intracellular functions for TRPM1 and TRPM2.Sarcoplasmic reticulum function in smooth muscle.Cyclic ADP-Ribose and NAADP in Vascular Regulation and Diseases.The role of transient receptor potential cation channels in Ca2+ signalingThe endo-lysosomal system as an NAADP-sensitive acidic Ca(2+) store: role for the two-pore channels.Physiological roles of NAADP-mediated Ca2+ signaling.
P2860
Q24316454-0E96A158-A678-4174-9B8B-7886D117CE3AQ28262391-AB6404A7-ACFD-4BD6-9286-2820526BBF1DQ28264441-405C78D3-F859-46D4-9403-44C9BF49F10FQ28265293-9A9F9F46-CC58-4DAD-89EE-71CD20948134Q28265825-7697EFD8-0400-4C34-87B9-BB57757C4DD6Q28271915-40D47040-5161-4C96-BE63-D2FC30190B64Q28286984-DB955AD7-F33B-40C9-8CE1-F76AF3ECF97CQ28302766-C343CB34-7EE4-4504-8554-FEEEDFDED038Q28476287-148510F2-7058-4010-AC5C-EA943C9C7A03Q30503399-F90D3A7F-BE60-4428-8868-1AC4B94E328CQ30835214-19669CC4-AA36-484F-93F5-0B4361C5A6E7Q33553835-9B538F01-A0FA-428A-BC26-86B84E12C6CAQ33838349-26F47439-6D1D-44D5-A6DD-860E33AE3541Q33840138-357B3240-0C37-4109-95F1-93AB28DEF6B4Q33840424-F9B8E037-8B69-4164-B7E9-904BBC621A5BQ33895752-B53C10CF-8676-4891-AC88-B1B16432AD41Q34001734-F348755D-EE5A-4149-BD63-C2BDAED71E4EQ34010331-DED112C5-6AC5-491E-9DA9-7EB91541AEF2Q34065665-61FEE50B-7D55-4E46-8E7A-8A58FC857BBAQ34147867-AD544445-B210-4F97-8113-958EAA564B83Q34359731-68FE954D-F5A7-4017-9D4C-A6D452DD76B6Q34483905-461FABF8-8D04-40F4-9042-A659AF6EA916Q34776238-7D30EC93-DA9B-4A01-AE0D-810A5DF0FEB3Q35067713-2EBA2648-08D6-4663-B27F-238D2379036AQ36126724-7A9C3884-473C-482F-BD65-AB1BB2B9F97CQ36760302-A55B9AE3-3DA6-4F18-A16D-DCEDF08DCFCCQ36890713-0E0F3192-7FB0-46D3-9A36-2368A38DD6B9Q37074786-A77B4036-23C3-4F67-80A5-FC8B043C703CQ37118266-877AD4E9-42B2-40E7-8C60-82A2BB33490CQ37216903-E642B8D2-E571-4413-98EF-760356C3E3F2Q37229250-3F2727FA-A215-4257-A9D7-7DA88FF46B48Q37401394-9D2A8EDE-C497-448D-B80E-A480135B0A5FQ37498502-9EFAF833-1F28-41D8-A1C1-C6F0BBE69E7DQ37604358-12939F0F-06C7-4856-B929-9F4B766436F4Q37627045-90533939-0328-44DB-9187-35ABE38C6B24Q37677917-A00420B9-CEBE-4505-A789-468037A5F9C4Q37704928-26ECF631-07C0-4EF4-8595-2CB55BD4CD18Q37791280-A4D28583-A43C-4DF3-9F7F-7FA91CCA7B3CQ37870269-A93C50B0-A9E2-485E-BBD3-7C04E50BD3AEQ37904890-8912D425-7002-49F0-829F-A2568AF0793A
P2860
Reconstitution and characterization of a nicotinic acid adenine dinucleotide phosphate (NAADP)-sensitive Ca2+ release channel from liver lysosomes of rats
description
2007 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2007 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
article publié dans la revue scientifique Journal of Biological Chemistry
@fr
artículu científicu espublizáu en 2007
@ast
im August 2007 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2007/08/31)
@sk
vědecký článek publikovaný v roce 2007
@cs
wetenschappelijk artikel (gepubliceerd op 2007/08/31)
@nl
наукова стаття, опублікована в серпні 2007
@uk
name
Reconstitution and characteriz ...... l from liver lysosomes of rats
@ast
Reconstitution and characteriz ...... l from liver lysosomes of rats
@en
Reconstitution and characteriz ...... l from liver lysosomes of rats
@nl
type
label
Reconstitution and characteriz ...... l from liver lysosomes of rats
@ast
Reconstitution and characteriz ...... l from liver lysosomes of rats
@en
Reconstitution and characteriz ...... l from liver lysosomes of rats
@nl
prefLabel
Reconstitution and characteriz ...... l from liver lysosomes of rats
@ast
Reconstitution and characteriz ...... l from liver lysosomes of rats
@en
Reconstitution and characteriz ...... l from liver lysosomes of rats
@nl
P2860
P356
P1476
Reconstitution and characteriz ...... l from liver lysosomes of rats
@en
P2093
P2860
P304
25259–25269
P356
10.1074/JBC.M701614200
P407
P577
2007-08-31T00:00:00Z