Membrane potential regulates nicotinic acid adenine dinucleotide phosphate (NAADP) dependence of the pH- and Ca2+-sensitive organellar two-pore channel TPC1
about
Two-pore channels function in calcium regulation in sea star oocytes and embryos.Regulation of lysosomal ion homeostasis by channels and transportersTwo-pore channels at the intersection of endolysosomal membrane trafficReconstituted human TPC1 is a proton-permeable ion channel and is activated by NAADP or Ca2+Expression of Ca²⁺-permeable two-pore channels rescues NAADP signalling in TPC-deficient cellsTPC: the NAADP discovery channel?Bidirectional Ca²⁺ signaling occurs between the endoplasmic reticulum and acidic organellesTwo-pore channels (TPCs): current controversiesConvergent regulation of the lysosomal two-pore channel-2 by Mg²⁺, NAADP, PI(3,5)P₂ and multiple protein kinasesThe voltage-gated sodium channel TPC1 confers endolysosomal excitability.Lysosomal physiology.Function and dysfunction of two-pore channels.Nicotinic Acid Adenine Dinucleotide Phosphate (NAADP) and Endolysosomal Two-pore Channels Modulate Membrane Excitability and Stimulus-Secretion Coupling in Mouse Pancreatic β Cells.Two-Pore Channels: Lessons from Mutant Mouse ModelsThe human two-pore channel 1 is modulated by cytosolic and luminal calcium.Two-pore channels provide insight into the evolution of voltage-gated Ca2+ and Na+ channels.The intracellular Ca²⁺ channels of membrane traffic.Characterization of Two-Pore Channel 2 by Nuclear Membrane ElectrophysiologyIntracellular sphingosine releases calcium from lysosomes.Nicotinic acid adenine dinucleotide phosphate (NAADP) activates global and heterogeneous local Ca2+ signals from NAADP- and ryanodine receptor-gated Ca2+ stores in pulmonary arterial myocytesMicroarray-Based Comparisons of Ion Channel Expression Patterns: Human Keratinocytes to Reprogrammed hiPSCs to Differentiated Neuronal and Cardiac Progeny.Calcium Signals from the Vacuole.Two-pore channels (TPCs): Novel voltage-gated ion channels with pleiotropic functions.Cyclic ADP-Ribose and NAADP in Vascular Regulation and Diseases.A link between LRRK2, autophagy and NAADP-mediated endolysosomal calcium signalling.Poring over two-pore channel pore mutants.TPC1 has two variant isoforms, and their removal has different effects on endo-lysosomal functions compared to loss of TPC2.On the structure and mechanism of two-pore channels.Questioning regulation of two-pore channels by NAADPActivity-Dependent Exocytosis of Lysosomes Regulates the Structural Plasticity of Dendritic Spines.A Link between Autophagy and the Pathophysiology of LRRK2 in Parkinson's Disease.The luminal Ca(2+) chelator, TPEN, inhibits NAADP-induced Ca(2+) release.The Molecular Basis for Ca2+ Signalling by NAADP: Two-Pore Channels in a Complex?The N-terminal region of two-pore channel 1 regulates trafficking and activation by NAADP.Structural insights into the voltage and phospholipid activation of the mammalian TPC1 channel.mTORC1 controls lysosomal Ca release through the two-pore channel TPC2
P2860
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P2860
Membrane potential regulates nicotinic acid adenine dinucleotide phosphate (NAADP) dependence of the pH- and Ca2+-sensitive organellar two-pore channel TPC1
description
2012 nî lūn-bûn
@nan
2012 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2012 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
name
Membrane potential regulates n ...... ganellar two-pore channel TPC1
@ast
Membrane potential regulates n ...... ganellar two-pore channel TPC1
@en
Membrane potential regulates n ...... ganellar two-pore channel TPC1
@nl
type
label
Membrane potential regulates n ...... ganellar two-pore channel TPC1
@ast
Membrane potential regulates n ...... ganellar two-pore channel TPC1
@en
Membrane potential regulates n ...... ganellar two-pore channel TPC1
@nl
prefLabel
Membrane potential regulates n ...... ganellar two-pore channel TPC1
@ast
Membrane potential regulates n ...... ganellar two-pore channel TPC1
@en
Membrane potential regulates n ...... ganellar two-pore channel TPC1
@nl
P2093
P2860
P3181
P356
P1476
Membrane potential regulates n ...... ganellar two-pore channel TPC1
@en
P2093
Dev Churamani
Jessica Coblentz
Krill Kiselyov
Malini Ahuja
Shmuel Muallem
Volodymyr Rybalchenko
P2860
P304
20407-20416
P3181
P356
10.1074/JBC.M112.359612
P407
P50
P577
2012-04-12T00:00:00Z