Akt1 regulates a JNK scaffold during excitotoxic apoptosis
about
Modulation of interleukin-1 transcriptional response by the interaction between VRK2 and the JIP1 scaffold proteinMutually exclusive subsets of BH3-only proteins are activated by the p53 and c-Jun N-terminal kinase/c-Jun signaling pathways during cortical neuron apoptosis induced by arseniteAkt phosphorylates acinus and inhibits its proteolytic cleavage, preventing chromatin condensationNeurotrophin-regulated signalling pathwaysSrc family kinases directly regulate JIP1 module dynamics and activationProtein Kinases and Parkinson's DiseaseAkt2 negatively regulates assembly of the POSH-MLK-JNK signaling complexRecruitment of JNK to JIP1 and JNK-dependent JIP1 phosphorylation regulates JNK module dynamics and activationArgBP2gamma interacts with Akt and p21-activated kinase-1 and promotes cell survivalPIKE (phosphatidylinositol 3-kinase enhancer)-A GTPase stimulates Akt activity and mediates cellular invasionCross-talk between JIP3 and JIP1 during glucose deprivation: SEK1-JNK2 and Akt1 act as mediatorsPhenethyl isothiocyanate exhibits antileukemic activity in vitro and in vivo by inactivation of Akt and activation of JNK pathwaysCritical role of PTEN in the coupling between PI3K/Akt and JNK1/2 signaling in ischemic brain injuryRegulation of the Pro-apoptotic scaffolding protein POSH by Akt.All Akt isoforms (Akt1, Akt2, Akt3) are involved in normal hearing, but only Akt2 and Akt3 are involved in auditory hair cell survival in the mammalian inner ear.A corticotropin-releasing factor system expressed in the cochlea modulates hearing sensitivity and protects against noise-induced hearing lossDCX, a new mediator of the JNK pathway.Use of RNA interference-mediated gene silencing and adenoviral overexpression to elucidate the roles of AKT/protein kinase B isoforms in insulin actions.Melatonin Induces Akt Phosphorylation through Melatonin Receptor- and PI3K-Dependent Pathways in Primary Astrocytes.Fibrinogen triggers astrocyte scar formation by promoting the availability of active TGF-beta after vascular damageDifferential vulnerability of neurons in Huntington's disease: the role of cell type-specific features.JNK regulates lifespan in Caenorhabditis elegans by modulating nuclear translocation of forkhead transcription factor/DAF-16.Notch interferes with the scaffold function of JNK-interacting protein 1 to inhibit the JNK signaling pathwayRequirement of JIP1-mediated c-Jun N-terminal kinase activation for obesity-induced insulin resistance.A crucial role for GRK2 in regulation of endothelial cell nitric oxide synthase function in portal hypertension.The endoplasmic reticulum stress sensor IRE1α protects cells from apoptosis induced by the coronavirus infectious bronchitis virusProgrammed cell death and new discoveries in the genetics of parkinsonism.Uses for JNK: the many and varied substrates of the c-Jun N-terminal kinases.Apigenin induces apoptosis in human leukemia cells and exhibits anti-leukemic activity in vivo.Control of oncogenesis and cancer therapy resistance.Targeting WNT, protein kinase B, and mitochondrial membrane integrity to foster cellular survival in the nervous system.Activating Akt and the brain's resources to drive cellular survival and prevent inflammatory injuryErythropoietin on a tightrope: balancing neuronal and vascular protection between intrinsic and extrinsic pathways.Ursolic acid induces apoptosis in human leukaemia cells and exhibits anti-leukaemic activity in nude mice through the PKB pathwayDistinct roles of Akt1 and Akt2 in regulating cell migration and epithelial-mesenchymal transition.Dissociation of Akt1 from its negative regulator JIP1 is mediated through the ASK1-MEK-JNK signal transduction pathway during metabolic oxidative stress: a negative feedback loop.Inhibition of mitogen-activated protein kinase and stimulation of Akt kinase signaling pathways: Two approaches with therapeutic potential in the treatment of neurodegenerative diseaseContext Specificity of Stress-activated Mitogen-activated Protein (MAP) Kinase Signaling: The Story as Told by Caenorhabditis elegans.Mixed lineage kinases (MLKs): a role in dendritic cells, inflammation and immunity?IGF-I attenuates FFA-induced activation of JNK1 phosphorylation and TNFα expression in human subcutaneous preadipocytes
P2860
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P2860
Akt1 regulates a JNK scaffold during excitotoxic apoptosis
description
2002 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2002
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im August 2002 veröffentlichter wissenschaftlicher Artikel
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scientific journal article
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vedecký článok (publikovaný 2002/08/15)
@sk
vědecký článek publikovaný v roce 2002
@cs
wetenschappelijk artikel (gepubliceerd op 2002/08/15)
@nl
наукова стаття, опублікована в серпні 2002
@uk
مقالة علمية (نشرت في 15-8-2002)
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name
Akt1 regulates a JNK scaffold during excitotoxic apoptosis
@ast
Akt1 regulates a JNK scaffold during excitotoxic apoptosis
@en
Akt1 regulates a JNK scaffold during excitotoxic apoptosis
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type
label
Akt1 regulates a JNK scaffold during excitotoxic apoptosis
@ast
Akt1 regulates a JNK scaffold during excitotoxic apoptosis
@en
Akt1 regulates a JNK scaffold during excitotoxic apoptosis
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prefLabel
Akt1 regulates a JNK scaffold during excitotoxic apoptosis
@ast
Akt1 regulates a JNK scaffold during excitotoxic apoptosis
@en
Akt1 regulates a JNK scaffold during excitotoxic apoptosis
@nl
P2093
P3181
P1433
P1476
Akt1 regulates a JNK scaffold during excitotoxic apoptosis
@en
P2093
Albert H Kim
Ben Margolis
Debra Meyer
Hiroko Yano
P304
P3181
P356
10.1016/S0896-6273(02)00821-8
P407
P577
2002-08-01T00:00:00Z