Differential vulnerability of neurons in Huntington's disease: the role of cell type-specific features.
about
Modeling Huntington's disease with induced pluripotent stem cellsMutant huntingtin downregulates myelin regulatory factor-mediated myelin gene expression and affects mature oligodendrocytesTranscriptome tomography for brain analysis in the web-accessible anatomical spaceThe ubiquitin proteasome system in glia and its role in neurodegenerative diseasesTranslating neurobehavioural endpoints of developmental neurotoxicity tests into in vitro assays and readoutsProbucol increases striatal glutathione peroxidase activity and protects against 3-nitropropionic acid-induced pro-oxidative damage in ratsAxonal transport and neurodegenerative disease: can we see the elephant?Restricted transgene expression in the brain with cell-type specific neuronal promoters.Striatal Vulnerability in Huntington's Disease: Neuroprotection Versus Neurotoxicity.Cell type-specific spatial and functional coupling between mammalian brain Kv2.1 K+ channels and ryanodine receptors.Impaired heat shock response in cells expressing full-length polyglutamine-expanded huntingtin.Protection by glia-conditioned medium in a cell model of Huntington diseaseDeep white matter in Huntington's diseaseEarly deficits in glycolysis are specific to striatal neurons from a rat model of huntington disease.Epigenetic dysregulation of hairy and enhancer of split 4 (HES4) is associated with striatal degeneration in postmortem Huntington brains.Specific reactions of different striatal neuron types in morphology induced by quinolinic acid in rats.Huntington's Disease: From Mutant Huntingtin Protein to Neurotrophic Factor Therapy.Cortical metabolites as biomarkers in the R6/2 model of Huntington's disease.Analysis of YFP(J16)-R6/2 reporter mice and postmortem brains reveals early pathology and increased vulnerability of callosal axons in Huntington's disease.Rhes: a GTP-binding protein integral to striatal physiology and pathology.Transcellular spreading of huntingtin aggregates in the Drosophila brain.Oscillating PDF in termini of circadian pacemaker neurons and synchronous molecular clocks in downstream neurons are not sufficient for sustenance of activity rhythms in constant darknessStriatal oligodendrogliogenesis and neuroblast recruitment are increased in the R6/2 mouse model of Huntington's diseaseMelatonin ameliorates injury and specific responses of ischemic striatal neurons in ratsWidespread AAV1- and AAV2-mediated transgene expression in the nonhuman primate brain: implications for Huntington's disease.Inhibition of mitochondrial fragmentation diminishes Huntington's disease-associated neurodegeneration.Proteostasis of polyglutamine varies among neurons and predicts neurodegeneration.Huntington's disease and the striatal medium spiny neuron: cell-autonomous and non-cell-autonomous mechanisms of diseaseThe mechanism of degeneration of striatal neuronal subtypes in Huntington diseaseOxidative metabolism and Ca2+ handling in striatal mitochondria from YAC128 mice, a model of Huntington's disease.The role of the cofilin-actin rod stress response in neurodegenerative diseases uncovers potential new drug targets.Regulation of motor proteins, axonal transport deficits and adult-onset neurodegenerative diseases.Impaired Levels of Gangliosides in the Corpus Callosum of Huntington Disease Animal ModelsThe heat shock response in neurons and astroglia and its role in neurodegenerative diseases.Protective Effects of Aqueous Extract of Luehea divaricata against Behavioral and Oxidative Changes Induced by 3-Nitropropionic Acid in Rats.The Ubiquitin-Proteasome System in Huntington's Disease: Are Proteasomes Impaired, Initiators of Disease, or Coming to the Rescue?Effects of eribulin, vincristine, paclitaxel and ixabepilone on fast axonal transport and kinesin-1 driven microtubule gliding: implications for chemotherapy-induced peripheral neuropathy.Voluntary saccade inhibition deficits correlate with extended white-matter cortico-basal atrophy in Huntington's disease.The Corticospinal Tract in Huntington's Disease.Early pridopidine treatment improves behavioral and transcriptional deficits in YAC128 Huntington disease mice.
P2860
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P2860
Differential vulnerability of neurons in Huntington's disease: the role of cell type-specific features.
description
2010 nî lūn-bûn
@nan
2010 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի մարտին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Differential vulnerability of ...... f cell type-specific features.
@ast
Differential vulnerability of ...... f cell type-specific features.
@en
type
label
Differential vulnerability of ...... f cell type-specific features.
@ast
Differential vulnerability of ...... f cell type-specific features.
@en
prefLabel
Differential vulnerability of ...... f cell type-specific features.
@ast
Differential vulnerability of ...... f cell type-specific features.
@en
P2093
P2860
P1476
Differential vulnerability of ...... f cell type-specific features.
@en
P2093
Gerardo A Morfini
Scott T Brady
P2860
P304
P356
10.1111/J.1471-4159.2010.06672.X
P407
P577
2010-03-17T00:00:00Z