Targeting of the 67-kDa isoform of glutamic acid decarboxylase to intracellular organelles is mediated by its interaction with the NH2-terminal region of the 65-kDa isoform of glutamic acid decarboxylase
about
betaIV spectrin, a new spectrin localized at axon initial segments and nodes of ranvier in the central and peripheral nervous systemMFR, a putative receptor mediating the fusion of macrophages.Two distinct mechanisms target GAD67 to vesicular pathways and presynaptic clustersGABA expression and regulation by sensory experience in the developing visual systemDemonstration of functional coupling between gamma -aminobutyric acid (GABA) synthesis and vesicular GABA transport into synaptic vesiclesCompartmentalization of GABA synthesis by GAD67 differs between pancreatic beta cells and neuronsOverexpression of Glutamate Decarboxylase in Mesenchymal Stem Cells Enhances Their Immunosuppressive Properties and Increases GABA and Nitric Oxide Levels.Cleft palate and decreased brain gamma-aminobutyric acid in mice lacking the 67-kDa isoform of glutamic acid decarboxylase.Molecular characterization of caveolin association with the Golgi complex: identification of a cis-Golgi targeting domain in the caveolin moleculeMotifs and structural fold of the cofactor binding site of human glutamate decarboxylaseThe role of the synthetic enzyme GAD65 in the control of neuronal gamma-aminobutyric acid release.Antigen presentation of detergent-free glutamate decarboxylase (GAD65) is affected by human serum albumin as carrier protein.GAD-reactive CD4+ Th1 cells induce diabetes in NOD/SCID mice.Transplantation of GABA-producing cells for seizure control in models of temporal lobe epilepsyAssessment of Developmental Toxicants using Human Embryonic Stem Cells.GABA(A) receptor and glycine receptor activation by paracrine/autocrine release of endogenous agonists: more than a simple communication pathway.Expression of properly folded human glutamate decarboxylase 65 as a fusion protein in Escherichia coli.The hydrophilic isoform of glutamate decarboxylase, GAD67, is targeted to membranes and nerve terminals independent of dimerization with the hydrophobic membrane-anchored isoform, GAD65.Mitochondrial heterogeneity in the brain at the cellular level.Glutamate-induced over-expression of GAD is down-regulated by acetyl-L-carnitine in rat islet cells.Post-translational modifications of ICA512, a receptor tyrosine phosphatase-like protein of secretory granules.Glutamate and GABA-metabolizing enzymes in post-mortem cerebellum in Alzheimer's disease: phosphate-activated glutaminase and glutamic acid decarboxylase.Antigen-presenting cells expressing glutamate decarboxylase 67 were identified as epithelial cells in glutamate decarboxylase 67-GFP knock-in mouse thymus.GADA and anti-ZnT8 complicate the outcome of phenotypic type 2 diabetes of adults.
P2860
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P2860
Targeting of the 67-kDa isoform of glutamic acid decarboxylase to intracellular organelles is mediated by its interaction with the NH2-terminal region of the 65-kDa isoform of glutamic acid decarboxylase
description
1995 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
1995 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
article publié dans la revue scientifique Journal of Biological Chemistry
@fr
artículu científicu espublizáu en 1995
@ast
im Februar 1995 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 1995/02/03)
@sk
vědecký článek publikovaný v roce 1995
@cs
wetenschappelijk artikel (gepubliceerd op 1995/02/03)
@nl
наукова стаття, опублікована в лютому 1995
@uk
name
Targeting of the 67-kDa isofor ...... of glutamic acid decarboxylase
@ast
Targeting of the 67-kDa isofor ...... of glutamic acid decarboxylase
@en
Targeting of the 67-kDa isofor ...... of glutamic acid decarboxylase
@nl
type
label
Targeting of the 67-kDa isofor ...... of glutamic acid decarboxylase
@ast
Targeting of the 67-kDa isofor ...... of glutamic acid decarboxylase
@en
Targeting of the 67-kDa isofor ...... of glutamic acid decarboxylase
@nl
prefLabel
Targeting of the 67-kDa isofor ...... of glutamic acid decarboxylase
@ast
Targeting of the 67-kDa isofor ...... of glutamic acid decarboxylase
@en
Targeting of the 67-kDa isofor ...... of glutamic acid decarboxylase
@nl
P2093
P2860
P3181
P356
P1476
Targeting of the 67-kDa isofor ...... of glutamic acid decarboxylase
@en
P2093
A. Lernmark
M. Solimena
P. De Camilli
R. S. Sherwin
P2860
P304
P3181
P356
10.1074/JBC.270.5.2241
P407
P577
1995-02-03T00:00:00Z