Synergistic interaction and the role of C-terminus in the activation of TRAAK K+ channels by pressure, free fatty acids and alkali
about
Functional properties of four splice variants of a human pancreatic tandem-pore K+ channel, TALK-1Crystal structure of the human two-pore domain potassium channel K2P1Crystal structure of the human K2P TRAAK, a lipid- and mechano-sensitive K+ ion channelInteraction with 14-3-3 proteins promotes functional expression of the potassium channels TASK-1 and TASK-3Domain-swapped chain connectivity and gated membrane access in a Fab-mediated crystal of the human TRAAK K+ channel.Two-pore Domain Potassium Channels in AstrocytesThermosensitivity of the two-pore domain K+ channels TREK-2 and TRAAKSeparate gating mechanisms mediate the regulation of K2P potassium channel TASK-2 by intra- and extracellular pHPolymodal activation of the TREK-2 K2P channel produces structurally distinct open statesFunctional role for Piezo1 in stretch-evoked Ca²⁺ influx and ATP release in urothelial cell cultures.An intracellular proton sensor commands lipid- and mechano-gating of the K(+) channel TREK-1.Lysophosphatidic acid-operated K+ channels.Deletion of TRAAK potassium channel affects brain metabolism and protects against ischemia.Modulation of TRESK background K+ channel by membrane stretchTransmembrane helix straightening and buckling underlies activation of mechanosensitive and thermosensitive K(2P) channels.Molecular aspects of structure, gating, and physiology of pH-sensitive background K2P and Kir K+-transport channels.Tubulin binds to the cytoplasmic loop of TRESK background K⁺ channel in vitro.Acid-sensitive ion channels and receptorsMolecular regulations governing TREK and TRAAK channel functions.A unique alkaline pH-regulated and fatty acid-activated tandem pore domain potassium channel (K₂P) from a marine sponge.Stretch-activated channels: a mini-review. Are stretch-activated channels an ocular barometer?Transcriptional expression of voltage-gated Na⁺ and voltage-independent K⁺ channels in the developing rat superficial dorsal horn.Heterodimerization within the TREK channel subfamily produces a diverse family of highly regulated potassium channels.Arachidonic acid and ion channels: an updateThe Inhibition of TREK2 Channel by an Oxidizing Agent, 5,5'-dithio-bis (2-nitrobenzoic acid), via Interaction with the C-terminus Distal to the 353rd Amino Acid.Mechanosensitivity is mediated directly by the lipid membrane in TRAAK and TREK1 K+ channels.Molecular physiology of pH-sensitive background K(2P) channels.A Role for K2P Channels in the Operation of Somatosensory NociceptorsThe CNS under pathophysiologic attack--examining the role of K₂p channels.The family of K2P channels: salient structural and functional properties.Much more than a leak: structure and function of K₂p-channels.Alkaline pH sensor molecules.Piezo channels and GsMTx4: Two milestones in our understanding of excitatory mechanosensitive channels and their role in pathology.Expression of thermosensitive two-pore domain K+ channels in human keratinocytes cell line HaCaT cells.alpha(1C) (Ca(V)1.2) L-type calcium channel mediates mechanosensitive calcium regulation.C-terminal charged cluster of MscL, RKKEE, functions as a pH sensorBackground and tandem-pore potassium channels in magnocellular neurosecretory cells of the rat supraoptic nucleus.PIP2 hydrolysis underlies agonist-induced inhibition and regulates voltage gating of two-pore domain K+ channels.TWIK-related two-pore domain potassium channel TREK-1 in carotid endothelium of normotensive and hypertensive mice.Zebrafish and mouse TASK-2 K(+) channels are inhibited by increased CO2 and intracellular acidification.
P2860
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P2860
Synergistic interaction and the role of C-terminus in the activation of TRAAK K+ channels by pressure, free fatty acids and alkali
description
2001 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2001
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im April 2001 veröffentlichter wissenschaftlicher Artikel
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scientific journal article
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vedecký článok (publikovaný 2001/04/01)
@sk
vědecký článek publikovaný v roce 2001
@cs
wetenschappelijk artikel (gepubliceerd op 2001/04/01)
@nl
наукова стаття, опублікована у квітні 2001
@uk
مقالة علمية (نشرت في أبريل 2001)
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name
Synergistic interaction and th ...... e, free fatty acids and alkali
@ast
Synergistic interaction and th ...... e, free fatty acids and alkali
@en
Synergistic interaction and th ...... e, free fatty acids and alkali
@nl
type
label
Synergistic interaction and th ...... e, free fatty acids and alkali
@ast
Synergistic interaction and th ...... e, free fatty acids and alkali
@en
Synergistic interaction and th ...... e, free fatty acids and alkali
@nl
prefLabel
Synergistic interaction and th ...... e, free fatty acids and alkali
@ast
Synergistic interaction and th ...... e, free fatty acids and alkali
@en
Synergistic interaction and th ...... e, free fatty acids and alkali
@nl
P2093
P3181
P356
P1433
P1476
Synergistic interaction and th ...... e, free fatty acids and alkali
@en
P2093
P2888
P3181
P356
10.1007/S004240000496
P577
2001-04-01T00:00:00Z
P5875
P6179
1039927410