Sec24b selectively sorts Vangl2 to regulate planar cell polarity during neural tube closure - Wikidata - wikimedia - TriplyDB

Sec24b selectively sorts Vangl2 to regulate planar cell polarity during neural tube closure

Sec24b selectively sorts Vangl2 to regulate planar cell polarity during neural tube closure

http://www.wikidata.org/entity/Q28584955

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Mutations in the planar cell polarity genes CELSR1 and SCRIB are associated with the severe neural tube defect craniorachischisis Vesicle-mediated ER export of proteins and lipids Comparison of phenotypes between different vangl2 mutants demonstrates dominant effects of the Looptail mutation during hair cell development Molecular characterisation of endogenous Vangl2/Vangl1 heteromeric protein complexes Disruption of the Sec24d gene results in early embryonic lethality in the mouse Syndecan 4 interacts genetically with Vangl2 to regulate neural tube closure and planar cell polarity The novel mouse mutant, chuzhoi, has disruption of Ptk7 protein and exhibits defects in neural tube, heart and lung development and abnormal planar cell polarity in the ear.Role of chromatin remodeling gene Cecr2 in neurulation and inner ear development Rack1 is required for Vangl2 membrane localization and planar cell polarity signaling while attenuating canonical Wnt activity The trafficking protein Tmed2/p24beta(1) is required for morphogenesis of the mouse embryo and placenta Mice deficient in LMAN1 exhibit FV and FVIII deficiencies and liver accumulation of α1-antitrypsin Mammalian COPII coat component SEC24C is required for embryonic development in mice All Dact (Dapper/Frodo) scaffold proteins dimerize and exhibit conserved interactions with Vangl, Dvl, and serine/threonine kinases SEC24A deficiency lowers plasma cholesterol through reduced PCSK9 secretion.Dlg5 regulates dendritic spine formation and synaptogenesis by controlling subcellular N-cadherin localization.Distinct apical and basolateral mechanisms drive planar cell polarity-dependent convergent extension of the mouse neural plate.PTK7 regulates myosin II activity to orient planar polarity in the mammalian auditory epithelium.Genetics of auditory mechano-electrical transduction.Molecular analysis and intestinal expression of SAR1 genes and proteins in Anderson's disease (Chylomicron retention disease)Initiation of synapse formation by Wnt-induced MuSK endocytosis.Anderson's disease/chylomicron retention disease in a Japanese patient with uniparental disomy 7 and a normal SAR1B gene protein coding sequence Heterozygous Vangl2Looptail mice reveal novel roles for the planar cell polarity pathway in adult lung homeostasis and repair.Gipc1 has a dual role in Vangl2 trafficking and hair bundle integrity in the inner ear.Wolbachia bacteria reside in host Golgi-related vesicles whose position is regulated by polarity proteins Regulation of coat assembly--sorting things out at the ER.Brainstem respiratory oscillators develop independently of neuronal migration defects in the Wnt/PCP mouse mutant looptail.Genetic interactions between planar cell polarity genes cause diverse neural tube defects in mice.Absence of a red blood cell phenotype in mice with hematopoietic deficiency of SEC23B.Charting the secretory pathway in a simple eukaryote.Vangl-dependent planar cell polarity signalling is not required for neural crest migration in mammals.Molecular basis of LMAN1 in coordinating LMAN1-MCFD2 cargo receptor formation and ER-to-Golgi transport of FV/FVIII A forward genetic screen in mice identifies mutants with abnormal cortical patterning.Wnt signaling gradients establish planar cell polarity by inducing Vangl2 phosphorylation through Ror2 The serotonin transporter is an exclusive client of the coat protein complex II (COPII) component SEC24C.The Arf GAP CNT-2 regulates the apoptotic fate in C. elegans asymmetric neuroblast divisions Vangl1 and Vangl2: planar cell polarity components with a developing role in cancer.Identification of novel CELSR1 mutations in spina bifida.Evidence for the involvement of the Arabidopsis SEC24A in male transmission Planar cell polarity signaling in craniofacial development.Phosphoregulatory protein 14-3-3 facilitates SAC1 transport from the endoplasmic reticulum.

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P2860

Sec24b selectively sorts Vangl2 to regulate planar cell polarity during neural tube closure

http://www.wikidata.org/entity/Q28584955

description

2010 թուականի Յունուարին հրատարակուած գիտական յօդուած

@hyw

2010 թվականի հունվարին հրատարակված գիտական հոդված

@hy

artikull shkencor

@sq

artículu científicu espublizáu en 2010

@ast

im Januar 2010 veröffentlichter wissenschaftlicher Artikel

@de

scientific journal article

@en

wetenschappelijk artikel

@nl

наукова стаття, опублікована в січні 2010

@uk

مقالة علمية (نشرت عام 2010)

@ar

name

Sec24b selectively sorts Vangl ...... ity during neural tube closure

@ast

Sec24b selectively sorts Vangl ...... ity during neural tube closure

@en

Sec24b selectively sorts Vangl ...... ity during neural tube closure

@nl

type

label

Sec24b selectively sorts Vangl ...... ity during neural tube closure

@ast

Sec24b selectively sorts Vangl ...... ity during neural tube closure

@en

Sec24b selectively sorts Vangl ...... ity during neural tube closure

@nl

prefLabel

Sec24b selectively sorts Vangl ...... ity during neural tube closure

@ast

Sec24b selectively sorts Vangl ...... ity during neural tube closure

@en

Sec24b selectively sorts Vangl ...... ity during neural tube closure

@nl

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Nature Cell Biology

P1476

Sec24b selectively sorts Vangl ...... ity during neural tube closure

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P2093

Devon Jensen

http://www.w3.org/2001/XMLSchema#string

Janna Merte

http://www.w3.org/2001/XMLSchema#string

Kevin Wright

http://www.w3.org/2001/XMLSchema#string

Sarah Sarsfield

http://www.w3.org/2001/XMLSchema#string

Yanshu Wang

http://www.w3.org/2001/XMLSchema#string

P2860

A phenotype-based screen for embryonic lethal mutations in the mouse.

Structure of the Sec23/24-Sar1 pre-budding complex of the COPII vesicle coat

Multiple cargo binding sites on the COPII subunit Sec24p ensure capture of diverse membrane proteins into transport vesicles.

Cargo selection into COPII vesicles is driven by the Sec24p subunit.

Lst1p and Sec24p cooperate in sorting of the plasma membrane ATPase into COPII vesicles in Saccharomyces cerevisiae.

Mutation of Celsr1 disrupts planar polarity of inner ear hair cells and causes severe neural tube defects in the mouse

Convergent extension: the molecular control of polarized cell movement during embryonic development

Disruption of scribble (Scrb1) causes severe neural tube defects in the circletail mouse

Wnt5a functions in planar cell polarity regulation in mice.

Dishevelled 2 is essential for cardiac outflow tract development, somite segmentation and neural tube closure

P2888

P304

41–46; sup pp 1-8

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scholarly article

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2047283

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P356

10.1038/NCB2002

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1

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12

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19966784

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P921

Amyloid beta (A4) precursor protein

Catenin (cadherin associated protein), beta 1

VANGL planar cell polarity 2

Frizzled class receptor 3

GTP-binding protein SAR1a

Lectin, mannose-binding, 1

SEC13 homolog, nuclear pore and COPII coat complex component

Prolyl 4-hydroxylase, beta polypeptide

SEC23 homolog A, COPII coat complex component

SEC23 homolog B, COPII coat complex component

P932

2823131

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