Presenilin/gamma-secretase-dependent processing of beta-amyloid precursor protein regulates EGF receptor expression
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Transthyretin and the brain re-visited: is neuronal synthesis of transthyretin protective in Alzheimer's disease?Presenilin modulates EGFR signaling and cell transformation by regulating the ubiquitin ligase Fbw7Sorting nexin 12 interacts with BACE1 and regulates BACE1-mediated APP processingSuppressor role of activating transcription factor 2 (ATF2) in skin cancerAmyloid precursor protein regulates brain apolipoprotein E and cholesterol metabolism through lipoprotein receptor LRP1Soluble amyloid precursor protein (APP) regulates transthyretin and Klotho gene expression without rescuing the essential function of APPInsights into the physiological function of the β-amyloid precursor protein: beyond Alzheimer's diseaseTargeting γ-secretase in breast cancerAmyloid β precursor protein as a molecular target for amyloid β--induced neuronal degeneration in Alzheimer's diseaseNeuregulin 1 improves cognitive deficits and neuropathology in an Alzheimer's disease model.APP processing in Alzheimer's diseaseProteolytic processing of Alzheimer's β-amyloid precursor proteinThe Ubiquitin-Proteasome System and Molecular Chaperone Deregulation in Alzheimer's DiseaseΓ-secretase components as predictors of breast cancer outcomeAmyloid precursor protein trafficking, processing, and functionEpidermal growth factor receptor is a preferred target for treating amyloid-β-induced memory loss.Co-localization of the amyloid precursor protein and Notch intracellular domains in nuclear transcription factories.FoxO mediates APP-induced AICD-dependent cell death.Role of X11 and ubiquilin as in vivo regulators of the amyloid precursor protein in DrosophilaGenomic convergence and network analysis approach to identify candidate genes in Alzheimer's disease.Comparative transcriptome profiling of amyloid precursor protein family members in the adult cortexIdentification and characterization of a neuronal enriched novel transcript encoding the previously described p60Fe65 isoform.AICD Overexpression in Neuro 2A Cells Regulates Expression of PTCH1 and TRPC5.Transient axonal glycoprotein-1 induces apoptosis-related gene expression without triggering apoptosis in U251 glioma cellsMolecular signatures in post-mortem brain tissue of younger individuals at high risk for Alzheimer's disease as based on APOE genotype.Central role of the EGF receptor in neurometabolic aging.The γ-secretase complex: from structure to function.Genome-wide identification of molecular pathways and biomarkers in response to arsenic exposure in zebrafish liver.Epigenetic induction of EGR-1 expression by the amyloid precursor protein during exposure to novelty.Intracellular APP Domain Regulates Serine-Palmitoyl-CoA Transferase Expression and Is Affected in Alzheimer's Disease.APP regulates NGF receptor trafficking and NGF-mediated neuronal differentiation and survival.p53-dependent control of transactivation of the Pen2 promoter by presenilinsAmyloid Precursor Protein Translation Is Regulated by a 3'UTR Guanine QuadruplexDAP12 Stabilizes the C-terminal Fragment of the Triggering Receptor Expressed on Myeloid Cells-2 (TREM2) and Protects against LPS-induced Pro-inflammatory Response.Presenilin 1 is necessary for neuronal, but not glial, EGFR expression and neuroprotection via γ-secretase-independent transcriptional mechanisms.All in the Family: How the APPs Regulate NeurogenesisAmyloid Precursor Protein (APP) Metabolites APP Intracellular Fragment (AICD), Aβ42, and Tau in Nuclear Roles.Appoptosin is a novel pro-apoptotic protein and mediates cell death in neurodegeneration.Evidence that the Amyloid beta Precursor Protein-intracellular domain lowers the stress threshold of neurons and has a "regulated" transcriptional roleHistopathological and molecular heterogeneity among individuals with dementia associated with Presenilin mutations
P2860
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P248
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P2860
Presenilin/gamma-secretase-dependent processing of beta-amyloid precursor protein regulates EGF receptor expression
description
2007 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2007 թվականի հունիսին հրատարակված գիտական հոդված
@hy
article publié dans les Procee ...... f the United States of America
@fr
artículu científicu espublizáu en 2007
@ast
im Juni 2007 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2007/06/19)
@sk
vědecký článek publikovaný v roce 2007
@cs
wetenschappelijk artikel (gepubliceerd op 2007/06/19)
@nl
наукова стаття, опублікована в червні 2007
@uk
name
Presenilin/gamma-secretase-dep ...... ulates EGF receptor expression
@ast
Presenilin/gamma-secretase-dep ...... ulates EGF receptor expression
@en
Presenilin/gamma-secretase-dep ...... ulates EGF receptor expression
@nl
type
label
Presenilin/gamma-secretase-dep ...... ulates EGF receptor expression
@ast
Presenilin/gamma-secretase-dep ...... ulates EGF receptor expression
@en
Presenilin/gamma-secretase-dep ...... ulates EGF receptor expression
@nl
prefLabel
Presenilin/gamma-secretase-dep ...... ulates EGF receptor expression
@ast
Presenilin/gamma-secretase-dep ...... ulates EGF receptor expression
@en
Presenilin/gamma-secretase-dep ...... ulates EGF receptor expression
@nl
P2093
P2860
P921
P3181
P356
P1476
Presenilin/gamma-secretase-dep ...... ulates EGF receptor expression
@en
P2093
Francesca-Fang Liao
Ruishan Wang
Yun-wu Zhang
P2860
P304
10613–10618
P3181
P356
10.1073/PNAS.0703903104
P407
P577
2007-06-19T00:00:00Z