A NUDEL-dependent mechanism of neurofilament assembly regulates the integrity of CNS neurons
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The cytoskeletal protein Ndel1 regulates dynamin 2 GTPase activityInhibition of NUDEL (nuclear distribution element-like)-oligopeptidase activity by disrupted-in-schizophrenia 1Functional genomics in postmortem human brain: abnormalities in a DISC1 molecular pathway in schizophreniaIntermediate Filaments and Polarization in the Intestinal EpitheliumHerpesviruses and intermediate filaments: close encounters with the third typeRegulation of the actin cytoskeleton by the Ndel1-Tara complex is critical for cell migration.A frameshift mutation in Disrupted in Schizophrenia 1 in an American family with schizophrenia and schizoaffective disorderDisrupted-In-Schizophrenia 1 regulates integration of newly generated neurons in the adult brainNdel1 promotes axon regeneration via intermediate filamentsSIRT1 deacetylase protects against neurodegeneration in models for Alzheimer's disease and amyotrophic lateral sclerosisLis1 is essential for cortical microtubule organization and desmosome stability in the epidermisp600 regulates spindle orientation in apical neural progenitors and contributes to neurogenesis in the developing neocortex.Morphological homeostasis in cortical dendrites.Identification of a novel dynein binding domain in nudel essential for spindle pole organization in Xenopus egg extractGenetic mosaic dissection of Lis1 and Ndel1 in neuronal migrationRequirement for Nudel and dynein for assembly of the lamin B spindle matrix.Mechanical systems biology of C. elegans touch sensation.Local translation of extranuclear lamin B promotes axon maintenanceMisfolded Gβ is recruited to cytoplasmic dynein by Nudel for efficient clearance.Nudel is crucial for the WAVE complex assembly in vivo by selectively promoting subcomplex stability and formation through direct interactions.APC binds intermediate filaments and is required for their reorganization during cell migration.Changes in the structural complexity of the aged brainA Ca2+-dependent mechanism of neuronal survival mediated by the microtubule-associated protein p600NDE1 and NDEL1: twin neurodevelopmental proteins with similar 'nature' but different 'nurture'.MSC p43 required for axonal development in motor neurons.The interaction of neurofilaments with the microtubule motor cytoplasmic dynein.Ndel1, Nudel (Noodle): flexible in the cell?Structures and interactions in 'bottlebrush' neurofilaments: the role of charged disordered proteins in forming hydrogel networks.NDE1 and NDEL1 from genes to (mal)functions: parallel but distinct roles impacting on neurodevelopmental disorders and psychiatric illness.Lessons from Animal Models of Cytoplasmic Intermediate Filament Proteins.Targeting protein for xenopus kinesin-like protein 2 (TPX2) regulates γ-histone 2AX (γ-H2AX) levels upon ionizing radiation.PKA phosphorylation of NDE1 is DISC1/PDE4 dependent and modulates its interaction with LIS1 and NDEL1Status epilepticus stimulates NDEL1 expression via the CREB/CRE pathway in the adult mouse brainControl of cortical microtubule organization and desmosome stability by centrosomal proteins.Neurofilament sidearms modulate parallel and crossed-filament orientations inducing nematic to isotropic and re-entrant birefringent hydrogels.Tangled NUDELs?Morphological determinants of dendritic arborization neurons in Drosophila larva.
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P2860
A NUDEL-dependent mechanism of neurofilament assembly regulates the integrity of CNS neurons
description
2004 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2004 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2004
@ast
im Juli 2004 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2004/07/01)
@sk
vědecký článek publikovaný v roce 2004
@cs
wetenschappelijk artikel (gepubliceerd op 2004/07/01)
@nl
наукова стаття, опублікована в липні 2004
@uk
مقالة علمية (نشرت في يوليو 2004)
@ar
name
A NUDEL-dependent mechanism of ...... s the integrity of CNS neurons
@ast
A NUDEL-dependent mechanism of ...... s the integrity of CNS neurons
@en
A NUDEL-dependent mechanism of ...... s the integrity of CNS neurons
@nl
type
label
A NUDEL-dependent mechanism of ...... s the integrity of CNS neurons
@ast
A NUDEL-dependent mechanism of ...... s the integrity of CNS neurons
@en
A NUDEL-dependent mechanism of ...... s the integrity of CNS neurons
@nl
prefLabel
A NUDEL-dependent mechanism of ...... s the integrity of CNS neurons
@ast
A NUDEL-dependent mechanism of ...... s the integrity of CNS neurons
@en
A NUDEL-dependent mechanism of ...... s the integrity of CNS neurons
@nl
P2093
P2860
P921
P3181
P356
P1433
P1476
A NUDEL-dependent mechanism of ...... s the integrity of CNS neurons
@en
P2093
Huang-Chun Tseng
Jean-Pierre Julien
Li-Huei Tsai
Minh Dang Nguyen
Sang Ki Park
Tianzhi Shu
P2860
P2888
P304
P3181
P356
10.1038/NCB1139
P577
2004-07-01T00:00:00Z
P5875
P6179
1006687135