Mouse deformed epidermal autoregulatory factor 1 recruits a LIM domain factor, LMO-4, and CLIM coregulators
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MLH3: a DNA mismatch repair gene associated with mammalian microsatellite instabilityThe LIM domain protein LMO4 interacts with the cofactor CtIP and the tumor suppressor BRCA1 and inhibits BRCA1 activityDeaf-1 regulates epithelial cell proliferation and side-branching in the mammary glandStructural and Functional Analysis of the DEAF-1 and BS69 MYND DomainsThe POU domain factor Skin-1a represses the keratin 14 promoter independent of DNA binding. A possible role for interactions between Skn-1a and CREB-binding protein/p300PDCD2 is a negative regulator of HCF-1 (C1)Islet-to-LMO stoichiometries control the function of transcription complexes that specify motor neuron and V2a interneuron identityNull mutation of the Lmo4 gene or a combined null mutation of the Lmo1/Lmo3 genes causes perinatal lethality, and Lmo4 controls neural tube development in miceA novel role for transcription factor Lmo4 in thymus development through genetic interaction with Cited2Defective neural tube closure and anteroposterior patterning in mice lacking the LIM protein LMO4 or its interacting partner Deaf-1Co-factors of LIM domains (Clims/Ldb/Nli) regulate corneal homeostasis and maintenance of hair follicle stem cellsMIZIP, a highly conserved, vertebrate specific melanin-concentrating hormone receptor 1 interacting zinc-finger protein.The LIM domain protein Lmo2 binds to AF6, a translocation partner of the MLL oncogene.In situ multiphoton optical tomography of hair follicles in mice.The highly related LIM factors, LMO1, LMO3 and LMO4, play different roles in the regulation of the pituitary glycoprotein hormone alpha-subunit (alpha GSU) gene.Screening candidate microRNAs (miRNAs) in different lambskin hair follicles in Hu sheep.The LIM domain gene LMO4 inhibits differentiation of mammary epithelial cells in vitro and is overexpressed in breast cancer.The co-factor of LIM domains (CLIM/LDB/NLI) maintains basal mammary epithelial stem cells and promotes breast tumorigenesis.Contribution of DEAF1 structural domains to the interaction with the breast cancer oncogene LMO4.Modulation of the interleukin-6 receptor subunit glycoprotein 130 complex and its signaling by LMO4 interaction.Islet1 and its co-factor Ldb1 are expressed in quiescent cells of mouse intestinal epitheliumThe structure of an LIM-only protein 4 (LMO4) and Deformed epidermal autoregulatory factor-1 (DEAF1) complex reveals a common mode of binding to LMO4.Deformed epidermal autoregulatory factor-1 (DEAF1) interacts with the Ku70 subunit of the DNA-dependent protein kinase complex.Identification of a TAL1 target gene reveals a positive role for the LIM domain-binding protein Ldb1 in erythroid gene expression and differentiation.Expression of LMO4 and outcome in pancreatic ductal adenocarcinoma.LDB1 overexpression is a negative prognostic factor in colorectal cancer.Controlling Hox gene expression and activity to build the vertebrate axial skeleton.LIM-domain-only proteins: multifunctional nuclear transcription coregulators that interacts with diverse proteins.The LIM-only factor LMO4 regulates expression of the BMP7 gene through an HDAC2-dependent mechanism, and controls cell proliferation and apoptosis of mammary epithelial cells.The LIM-only protein, LMO4, and the LIM domain-binding protein, LDB1, expression in squamous cell carcinomas of the oral cavityE2F-HDAC complexes negatively regulate the tumor suppressor gene ARHI in breast cancer.LMO4 functions as a co-activator of neurogenin 2 in the developing cortex.LMO4 is an essential mediator of ErbB2/HER2/Neu-induced breast cancer cell cycle progression.Expression of an engrailed-LMO4 fusion protein in mammary epithelial cells inhibits mammary gland development in mice.The LIM-domain only protein 4 contributes to lung epithelial cell proliferation but is not essential for tumor progression.Requirement for Lmo4 in the vestibular morphogenesis of mouse inner ear.The LIM domain protein Lmo4 is highly expressed in proliferating mouse epithelial tissues.The sickness unto DeafLmo4 in the nucleus accumbens regulates cocaine sensitivityBackbone and side-chain assignments of a tethered complex between LMO4 and DEAF-1.
P2860
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P2860
Mouse deformed epidermal autoregulatory factor 1 recruits a LIM domain factor, LMO-4, and CLIM coregulators
description
1998 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
1998 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
article publié dans les Procee ...... f the United States of America
@fr
artículu científicu espublizáu en 1998
@ast
im Dezember 1998 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 1998/12/22)
@sk
vědecký článek publikovaný v roce 1998
@cs
wetenschappelijk artikel (gepubliceerd op 1998/12/22)
@nl
наукова стаття, опублікована в грудні 1998
@uk
name
Mouse deformed epidermal autor ...... , LMO-4, and CLIM coregulators
@ast
Mouse deformed epidermal autor ...... , LMO-4, and CLIM coregulators
@en
Mouse deformed epidermal autor ...... , LMO-4, and CLIM coregulators
@nl
type
label
Mouse deformed epidermal autor ...... , LMO-4, and CLIM coregulators
@ast
Mouse deformed epidermal autor ...... , LMO-4, and CLIM coregulators
@en
Mouse deformed epidermal autor ...... , LMO-4, and CLIM coregulators
@nl
prefLabel
Mouse deformed epidermal autor ...... , LMO-4, and CLIM coregulators
@ast
Mouse deformed epidermal autor ...... , LMO-4, and CLIM coregulators
@en
Mouse deformed epidermal autor ...... , LMO-4, and CLIM coregulators
@nl
P2093
P2860
P356
P1476
Mouse deformed epidermal autor ...... , LMO-4, and CLIM coregulators
@en
P2093
B. Andersen
M. G. Rosenfeld
T. M. Sugihara
P2860
P304
15418–15423
P356
10.1073/PNAS.95.26.15418
P407
P577
1998-12-22T00:00:00Z