Targeted deletion of protein kinase C lambda reveals a distribution of functions between the two atypical protein kinase C isoforms
about
Protein kinase C iota: human oncogene, prognostic marker and therapeutic targetInactivation of aPKClambda reveals a context dependent allocation of cell lineages in preimplantation mouse embryosProtein kinase C in the immune system: from signalling to chromatin regulationInvolvement of Girdin in the determination of cell polarity during cell migrationPhenotypical analysis of atypical PKCs in vivo function display a compensatory system at mouse embryonic day 7.5Essential role of PKC-zeta in normal and angiotensin II-accelerated neointimal growth after vascular injuryProtein kinase D2 potentiates MEK/ERK/RSK signaling, c-Fos accumulation and DNA synthesis induced by bombesin in Swiss 3T3 cellsPar6B and atypical PKC regulate mitotic spindle orientation during epithelial morphogenesisRegulation of neural progenitor cell motility by ceramide and potential implications for mouse brain developmentAtypical protein kinase C expression in phrenic motor neurons of the rat.Protein kinase Cδ is a therapeutic target in malignant melanoma with NRAS mutation.Ceramide regulates atypical PKCzeta/lambda-mediated cell polarity in primitive ectoderm cells. A novel function of sphingolipids in morphogenesis.Zebrafish pronephros tubulogenesis and epithelial identity maintenance are reliant on the polarity proteins Prkc iota and zeta.Protein complexes that control renal epithelial polarity.Regulation of glioblastoma cell invasion by PKC iota and RhoB.Protein kinase C zeta regulates human pancreatic cancer cell transformed growth and invasion through a STAT3-dependent mechanismRegulation of asymmetric division and CD8+ T lymphocyte fate specification by protein kinase Cζ and protein kinase Cλ/ι.Anergic CD8+ T lymphocytes have impaired NF-κB activation with defects in p65 phosphorylation and acetylationTh1/Th2 Differentiation and B Cell Function by the Atypical PKCs and Their Regulators.Atypical PKC-iota Controls Stem Cell Expansion via Regulation of the Notch Pathway.Functional comparison of protein domains within aPKCs involved in nucleocytoplasmic shuttling.aPKCλ/ι and aPKCζ contribute to podocyte differentiation and glomerular maturation.Protein kinase C isozymes as therapeutic targets for treatment of human cancers.Asymmetric cell division of T cells upon antigen presentation uses multiple conserved mechanisms.Interruption of RNA processing machinery by a small compound, 1-[(4-chlorophenyl)methyl]-1H-indole-3-carboxaldehyde (oncrasin-1).aPKCλ controls epidermal homeostasis and stem cell fate through regulation of division orientationAtypical protein kinase Cλ is critical for growth factor receptor-induced dorsal ruffle turnover and cell migrationAtypical protein kinase C activity in the hypothalamus is required for lipopolysaccharide-mediated sickness responses.Of the atypical PKCs, Par-4 and p62: recent understandings of the biology and pathology of a PB1-dominated complex.Polarized cells, polarized views: asymmetric cell division in hematopoietic cells.Protein kinase C inhibitors for immune disorders.DIDO as a Switchboard that Regulates Self-Renewal and Differentiation in Embryonic Stem Cells.Knockout of the PKN Family of Rho Effector Kinases Reveals a Non-redundant Role for PKN2 in Developmental Mesoderm ExpansionAtypical protein kinase C activity is required for extracellular matrix degradation and invasion by Src-transformed cellsThe carboxyl-terminal domain of atypical protein kinase Czeta binds to ceramide and regulates junction formation in epithelial cells.Atypical protein kinase Ciota plays a critical role in human lung cancer cell growth and tumorigenicity.Atypical Protein Kinase C-Dependent Polarized Cell Division Is Required for Myocardial Trabeculation.Analysis of aPKClambda and aPKCzeta reveals multiple and redundant functions during vertebrate retinogenesis.Regulation of mitochondrial function and cellular energy metabolism by protein kinase C-λ/ι: a novel mode of balancing pluripotency.Loss of podocyte aPKClambda/iota causes polarity defects and nephrotic syndrome.
P2860
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P2860
Targeted deletion of protein kinase C lambda reveals a distribution of functions between the two atypical protein kinase C isoforms
description
2004 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2004 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2004
@ast
im September 2004 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2004/09/01)
@sk
vědecký článek publikovaný v roce 2004
@cs
wetenschappelijk artikel (gepubliceerd op 2004/09/01)
@nl
наукова стаття, опублікована у вересні 2004
@uk
مقالة علمية (نشرت في سبتمبر 2004)
@ar
name
Targeted deletion of protein k ...... ical protein kinase C isoforms
@ast
Targeted deletion of protein k ...... ical protein kinase C isoforms
@en
Targeted deletion of protein k ...... ical protein kinase C isoforms
@nl
type
label
Targeted deletion of protein k ...... ical protein kinase C isoforms
@ast
Targeted deletion of protein k ...... ical protein kinase C isoforms
@en
Targeted deletion of protein k ...... ical protein kinase C isoforms
@nl
prefLabel
Targeted deletion of protein k ...... ical protein kinase C isoforms
@ast
Targeted deletion of protein k ...... ical protein kinase C isoforms
@en
Targeted deletion of protein k ...... ical protein kinase C isoforms
@nl
P2093
P1476
Targeted deletion of protein k ...... ical protein kinase C isoforms
@en
P2093
Carol Katayama
James R. Feramisco
Meei Yun Lin
Rachel S. Soloff
Stephen M. Hedrick
P304
P356
10.4049/JIMMUNOL.173.5.3250
P407
P577
2004-09-01T00:00:00Z