Domain-specific gene disruption reveals critical regulation of neuregulin signaling by its cytoplasmic tail - Wikidata - wikimedia - TriplyDB

Domain-specific gene disruption reveals critical regulation of neuregulin signaling by its cytoplasmic tail

Domain-specific gene disruption reveals critical regulation of neuregulin signaling by its cytoplasmic tail

http://www.wikidata.org/entity/Q28590093

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Neuregulin 1 and susceptibility to schizophrenia.Mechanisms of neuregulin action Distinct phenotypes of new transmembrane-domain neuregulin 1 mutant mice and the rescue effects of valproate on the observed schizophrenia-related cognitive deficits Metalloproteinase-dependent cleavage of neuregulin and autocrine stimulation of vascular endothelial cells.Comprehensive analysis of NRG1 common and rare variants in Hirschsprung patients Neuregulins and the shaping of synapses.ErbB signaling in cardiac development and disease.Endothelial Jarid2/Jumonji is required for normal cardiac development and proper Notch1 expression Transautocrine signaling by membrane neuregulins requires cell surface targeting, which is controlled by multiple domains Neuregulin-1β for the treatment of systolic heart failure.Multiple personalities of neuregulin gene family members.Neuregulin-1 Administration Protocols Sufficient for Stimulating Cardiac Regeneration in Young Mice Do Not Induce Somatic, Organ, or Neoplastic Growth.Distinct Intracellular Domain Substrate Modifications Selectively Regulate Ectodomain Cleavage of NRG1 or CD44.Back signaling by the Nrg-1 intracellular domain Neuregulin in cardiovascular development and disease The role of Neuregulin-1beta/ErbB signaling in the heart.Neuregulin 1 in neural development, synaptic plasticity and schizophrenia.Metalloprotease-mediated ligand release regulates autocrine signaling through the epidermal growth factor receptor.Neuregulin-1 beta is associated with disease severity and adverse outcomes in chronic heart failure.Neurotrophins induce neuregulin release through protein kinase Cdelta activation.Signalling between microvascular endothelium and cardiomyocytes through neuregulin.Parenteral administration of recombinant human neuregulin-1 to patients with stable chronic heart failure produces favourable acute and chronic haemodynamic responses.Endogenous expression of Neuregulin-1 (Nrg1) as a potential modulator of prolactin (PRL) secretion in GH3 cells.Intact intracellular tail is critical for proper functioning of the tumor-associated, hypoxia-regulated carbonic anhydrase IX.Mitogen-activated protein kinase-dependent and -independent routes control shedding of transmembrane growth factors through multiple secretases.Gamma-heregulin: a fusion gene of DOC-4 and neuregulin-1 derived from a chromosome translocation.The N-terminal cytoplasmic domain of neuregulin 1 type III is intrinsically disordered.Synergistic roles of neuregulin-1 and insulin-like growth factor-I in activation of the phosphatidylinositol 3-kinase pathway and cardiac chamber morphogenesis.Neuregulin1 and ErbB expression in the uninjured and regenerating olfactory mucosa.In silico analysis of neuregulin 1 evolution in vertebrates.Protein processing and releases of neuregulin-1 are regulated in an activity-dependent manner.Release of the neuregulin functional polypeptide requires its cytoplasmic tail.Mutations in the NRG1 gene are associated with Hirschsprung disease

P2860

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P2860

Domain-specific gene disruption reveals critical regulation of neuregulin signaling by its cytoplasmic tail

http://www.wikidata.org/entity/Q28590093

description

1998 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած

@hyw

1998 թվականի հոտեմբերին հրատարակված գիտական հոդված

@hy

article publié dans les Procee ...... f the United States of America

@fr

artículu científicu espublizáu en 1998

@ast

im Oktober 1998 veröffentlichter wissenschaftlicher Artikel

@de

scientific journal article

@en

vedecký článok (publikovaný 1998/10/27)

@sk

vědecký článek publikovaný v roce 1998

@cs

wetenschappelijk artikel (gepubliceerd op 1998/10/27)

@nl

наукова стаття, опублікована в жовтні 1998

@uk

name

Domain-specific gene disruptio ...... naling by its cytoplasmic tail

@ast

Domain-specific gene disruptio ...... naling by its cytoplasmic tail

@en

Domain-specific gene disruptio ...... naling by its cytoplasmic tail

@nl

type

label

Domain-specific gene disruptio ...... naling by its cytoplasmic tail

@ast

Domain-specific gene disruptio ...... naling by its cytoplasmic tail

@en

Domain-specific gene disruptio ...... naling by its cytoplasmic tail

@nl

prefLabel

Domain-specific gene disruptio ...... naling by its cytoplasmic tail

@ast

Domain-specific gene disruptio ...... naling by its cytoplasmic tail

@en

Domain-specific gene disruptio ...... naling by its cytoplasmic tail

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P1433

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PNAS.95.22.13024

P1433

Proceedings of the National Academy of Sciences of the United States of America

P1476

Domain-specific gene disruptio ...... naling by its cytoplasmic tail

@en

P2093

A. Cunningham

http://www.w3.org/2001/XMLSchema#string

H. Hwang

http://www.w3.org/2001/XMLSchema#string

J. Chen

http://www.w3.org/2001/XMLSchema#string

K. R. Chien

http://www.w3.org/2001/XMLSchema#string

L. Cao

http://www.w3.org/2001/XMLSchema#string

M. Buckland

http://www.w3.org/2001/XMLSchema#string

M. Zhou

http://www.w3.org/2001/XMLSchema#string

R. M. Graham

http://www.w3.org/2001/XMLSchema#string

X. Liu

http://www.w3.org/2001/XMLSchema#string

P2860

Glial growth factors are alternatively spliced erbB2 ligands expressed in the nervous system

Aberrant neural and cardiac development in mice lacking the ErbB4 neuregulin receptor

Multiple essential functions of neuregulin in development

Neuregulins with an Ig-like domain are essential for mouse myocardial and neuronal development

Disruption of the proto-oncogene int-2 in mouse embryo-derived stem cells: a general strategy for targeting mutations to non-selectable genes

Targeted disruption of the c-src proto-oncogene leads to osteopetrosis in mice

Axon-induced mitogenesis of human Schwann cells involves heregulin and p185erbB2.

ARIA, a protein that stimulates acetylcholine receptor synthesis, is a member of the neu ligand family.

Axonal neuregulin signals cells of the oligodendrocyte lineage through activation of HER4 and Schwann cells through HER2 and HER3.

Structural and functional aspects of the multiplicity of Neu differentiation factors.

P304

13024–13029

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P31

scholarly article

P3181

1660006

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P356

10.1073/PNAS.95.22.13024

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22

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1998-10-27T00:00:00Z

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13497420

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9789034

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23694

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