Release of the neuregulin functional polypeptide requires its cytoplasmic tail.
about
CALEB/NGC interacts with the Golgi-associated protein PISTAutolytic processing at Glu586-Ser587 within the cysteine-rich domain of human adamalysin 19/disintegrin-metalloproteinase 19 is necessary for its proteolytic activityDomain-specific gene disruption reveals critical regulation of neuregulin signaling by its cytoplasmic tailDistinct phenotypes of new transmembrane-domain neuregulin 1 mutant mice and the rescue effects of valproate on the observed schizophrenia-related cognitive deficitsExpression of transmembrane serine protease TMPRSS2 in mouse and human tissues.Rhomboid and Star facilitate presentation and processing of the Drosophila TGF-alpha homolog SpitzMetalloproteinase-dependent cleavage of neuregulin and autocrine stimulation of vascular endothelial cells.Comprehensive analysis of NRG1 common and rare variants in Hirschsprung patientsNeuregulins and the shaping of synapses.Activity-dependent transcription regulation of PSD-95 by neuregulin-1 and Eos.Transautocrine signaling by membrane neuregulins requires cell surface targeting, which is controlled by multiple domainsEffects of schizophrenia risk variation in the NRG1 gene on NRG1-IV splicing during fetal and early postnatal human neocortical development.Multiple personalities of neuregulin gene family members.Inside-out Regulation of Ectodomain Cleavage of Cluster-of-Differentiation-44 (CD44) and of Neuregulin-1 Requires Substrate Dimerization.Distinct Intracellular Domain Substrate Modifications Selectively Regulate Ectodomain Cleavage of NRG1 or CD44.Back signaling by the Nrg-1 intracellular domainA common missense variant in the neuregulin 1 gene is associated with both schizophrenia and sudden cardiac death.Neurotrophins induce neuregulin release through protein kinase Cdelta activation.A deletion mutant of heregulin increases the sensitivity of breast cancer cells to chemotherapy without promoting tumorigenicity.Expression in mammalian cell cultures reveals interdependent, but distinct, functions for Star and Rhomboid proteins in the processing of the Drosophila transforming-growth-factor-alpha homologue Spitz.Mitogen-activated protein kinase-dependent and -independent routes control shedding of transmembrane growth factors through multiple secretases.The proamphiregulin cytoplasmic domain is required for basolateral sorting, but is not essential for constitutive or stimulus-induced processing in polarized Madin-Darby canine kidney cells.Gamma-heregulin: a fusion gene of DOC-4 and neuregulin-1 derived from a chromosome translocation.The N-terminal cytoplasmic domain of neuregulin 1 type III is intrinsically disordered.Neuregulin1 and ErbB expression in the uninjured and regenerating olfactory mucosa.Protein processing and releases of neuregulin-1 are regulated in an activity-dependent manner.Cardiac functional improvement in rats with myocardial infarction by up-regulating cardiac myosin light chain kinase with neuregulin.Mutations in the NRG1 gene are associated with Hirschsprung disease
P2860
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P2860
Release of the neuregulin functional polypeptide requires its cytoplasmic tail.
description
1998 nî lūn-bûn
@nan
1998年の論文
@ja
1998年学术文章
@wuu
1998年学术文章
@zh-cn
1998年学术文章
@zh-hans
1998年学术文章
@zh-my
1998年学术文章
@zh-sg
1998年學術文章
@yue
1998年學術文章
@zh
1998年學術文章
@zh-hant
name
Release of the neuregulin functional polypeptide requires its cytoplasmic tail.
@en
Release of the neuregulin functional polypeptide requires its cytoplasmic tail.
@nl
type
label
Release of the neuregulin functional polypeptide requires its cytoplasmic tail.
@en
Release of the neuregulin functional polypeptide requires its cytoplasmic tail.
@nl
prefLabel
Release of the neuregulin functional polypeptide requires its cytoplasmic tail.
@en
Release of the neuregulin functional polypeptide requires its cytoplasmic tail.
@nl
P2093
P2860
P356
P1476
Release of the neuregulin functional polypeptide requires its cytoplasmic tail.
@en
P2093
P2860
P304
34335-34340
P356
10.1074/JBC.273.51.34335
P407
P577
1998-12-01T00:00:00Z