Proteolysis of AKAP121 regulates mitochondrial activity during cellular hypoxia and brain ischaemia
about
Control of PKA stability and signalling by the RING ligase praja2mAKAP compartmentalizes oxygen-dependent control of HIF-1alphaMitochondrial Dysfunction in Alzheimer's Disease and the Rationale for Bioenergetics Based TherapiesA dynamic interface between ubiquitylation and cAMP signalingRole of protein kinase A in regulating mitochondrial function and neuronal development: implications to neurodegenerative diseasesAkap1 Deficiency Promotes Mitochondrial Aberrations and Exacerbates Cardiac Injury Following Permanent Coronary Ligation via Enhanced Mitophagy and ApoptosisMechanism of neuroprotective mitochondrial remodeling by PKA/AKAP1Genome-wide map of nuclear protein degradation shows NCoR1 turnover as a key to mitochondrial gene regulationSuborganelle sensing of mitochondrial cAMP-dependent protein kinase activity.Compensatory proteome adjustments imply tissue-specific structural and metabolic reorganization following episodic hypoxia or anoxia in the epaulette shark (Hemiscyllium ocellatum).Hypoxic regulation of pulmonary vascular smooth muscle cyclic guanosine monophosphate-dependent kinase by the ubiquitin conjugating systemFine-tuning of Drp1/Fis1 availability by AKAP121/Siah2 regulates mitochondrial adaptation to hypoxia.Anchoring proteins as regulators of signaling pathways.Creating order from chaos: cellular regulation by kinase anchoring.Pivotal role of AKAP121 in mitochondrial physiology.Proteolysis of MOB1 by the ubiquitin ligase praja2 attenuates Hippo signalling and supports glioblastoma growth.PINK1 disables the anti-fission machinery to segregate damaged mitochondria for mitophagy.The role of the ubiquitin proteasome system in ischemia and ischemic tolerance.Mitochondrial protein phosphorylation: instigator or target of lipotoxicity?Mitochondria: a kinase anchoring protein 1, a signaling platform for mitochondrial form and function.Regulators and effectors of Siah ubiquitin ligases.Mitochondrial AKAP1 supports mTOR pathway and tumor growth.Regulation of mRNA following brain ischemia and reperfusion.Oxidative stress induced mitochondrial protein kinase A mediates cytochrome c oxidase dysfunction.PTPD1 supports receptor stability and mitogenic signaling in bladder cancer cellspraja2 regulates KSR1 stability and mitogenic signalingSeven in Absentia E3 Ubiquitin Ligases: Central Regulators of Neural Cell Fate and Neuronal Polarity.Induction of HIF-1alpha and the glycolytic pathway alters apoptotic and differentiation profiles of activated human T cells.Mitochondrial Reactive Oxygen Species in Lipotoxic Hearts Induces Post-Translational Modifications of AKAP121, DRP1 and OPA1 That Promote Mitochondrial Fission.MicroRNA-148a-3p enhances cisplatin cytotoxicity in gastric cancer through mitochondrial fission induction and cyto-protective autophagy suppression.PINK1 regulates mitochondrial trafficking in dendrites of cortical neurons through mitochondrial PKA.Regulation of Mitochondrial Dynamics and Autophagy by the Mitochondria-Associated Membrane.How AMPK and PKA Interplay to Regulate Mitochondrial Function and Survival in Models of Ischemia and Diabetes.Loss of Akap1 Exacerbates Pressure Overload-Induced Cardiac Hypertrophy and Heart Failure.Higher expression of A-kinase anchoring-protein 1 predicts poor prognosis in human hepatocellular carcinoma.AKAP1 Protects from Cerebral Ischemic Stroke by Inhibiting Drp1-Dependent Mitochondrial FissionAKAP121 downregulation impairs protective cAMP signals, promotes mitochondrial dysfunction, and increases oxidative stressMitochondrial dysfunction in cancer
P2860
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P2860
Proteolysis of AKAP121 regulates mitochondrial activity during cellular hypoxia and brain ischaemia
description
2008 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2008
@ast
im April 2008 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2008/04/09)
@sk
vědecký článek publikovaný v roce 2008
@cs
wetenschappelijk artikel (gepubliceerd op 2008/04/09)
@nl
наукова стаття, опублікована у квітні 2008
@uk
مقالة علمية نشرت في 9-4-2008 حول موضوع: دماغ
@ar
name
Proteolysis of AKAP121 regulat ...... ar hypoxia and brain ischaemia
@ast
Proteolysis of AKAP121 regulat ...... ar hypoxia and brain ischaemia
@en
Proteolysis of AKAP121 regulat ...... ar hypoxia and brain ischaemia
@nl
type
label
Proteolysis of AKAP121 regulat ...... ar hypoxia and brain ischaemia
@ast
Proteolysis of AKAP121 regulat ...... ar hypoxia and brain ischaemia
@en
Proteolysis of AKAP121 regulat ...... ar hypoxia and brain ischaemia
@nl
prefLabel
Proteolysis of AKAP121 regulat ...... ar hypoxia and brain ischaemia
@ast
Proteolysis of AKAP121 regulat ...... ar hypoxia and brain ischaemia
@en
Proteolysis of AKAP121 regulat ...... ar hypoxia and brain ischaemia
@nl
P2093
P2860
P50
P921
P3181
P356
P1433
P1476
Proteolysis of AKAP121 regulat ...... ar hypoxia and brain ischaemia
@en
P2093
Annalisa Carlucci
Antonella Scorziello
Mariapaola Foca
Max Gottesman
P2860
P304
P3181
P356
10.1038/EMBOJ.2008.33
P407
P577
2008-03-06T00:00:00Z