Liver-targeted disruption of Apc in mice activates beta-catenin signaling and leads to hepatocellular carcinomas
about
A Complex Interplay between Wnt/β-Catenin Signalling and the Cell Cycle in the Adult LiverFunctional interaction between Wnt3 and Frizzled-7 leads to activation of the Wnt/beta-catenin signaling pathway in hepatocellular carcinoma cellsAstrocyte elevated gene-1 regulates hepatocellular carcinoma development and progressionWnt signaling: the good and the badEpidermal growth factor receptor: a novel target of the Wnt/beta-catenin pathway in liverReport on the use of non-clinical studies in the regulatory evaluation of oncology drugsHepatocellular carcinoma mouse models: Hepatitis B virus-associated hepatocarcinogenesis and haploinsufficient tumor suppressor genesMouse models of liver cancer: Progress and recommendationsMouse models of cancer: Sleeping Beauty transposons for insertional mutagenesis screens and reverse genetic studiesA cryptic frizzled module in cell surface collagen 18 inhibits Wnt/beta-catenin signalingIdentification of Chemical Inhibitors of β-Catenin-Driven Liver Tumorigenesis in ZebrafishMouse models in liver cancer research: A review of current literatureGenetic alterations in hepatocellular carcinoma: An updateAberrant regulation of Wnt signaling in hepatocellular carcinomaPDGFRα in liver pathophysiology: emerging roles in development, regeneration, fibrosis, and cancerβ-Catenin Signaling and Roles in Liver Homeostasis, Injury, and TumorigenesisTumor suppressor and hepatocellular carcinomaDickkopfs and Wnt/β-catenin signalling in liver cancerGenetic dissection of differential signaling threshold requirements for the Wnt/beta-catenin pathway in vivoConstitutive turnover of cyclin E by Cul3 maintains quiescenceTranscriptomic characterization of hepatocellular carcinoma with CTNNB1 mutation.miR-372 down-regulates the oncogene ATAD2 to influence hepatocellular carcinoma proliferation and metastasis.Development of a mouse model for sporadic and metastatic colon tumors and its use in assessing drug treatment.Molecular genetics of hepatocellular neoplasia.Inducible loss of one Apc allele in Lrig1-expressing progenitor cells results in multiple distal colonic tumors with features of familial adenomatous polyposis.Expression of Wnt-5a and β-catenin in primary hepatocellular carcinoma.Role of Wnt/β-catenin signaling in liver metabolism and cancerCancer gene discovery in hepatocellular carcinomaOpposing effects of DNA hypomethylation on intestinal and liver carcinogenesisNf2/Merlin controls progenitor homeostasis and tumorigenesis in the liverLiver-specific β-catenin knockout mice have bile canalicular abnormalities, bile secretory defect, and intrahepatic cholestasis.MicroRNA-194 is a target of transcription factor 1 (Tcf1, HNF1α) in adult liver and controls expression of frizzled-6.The transcription factor c-Jun protects against liver damage following activated β-Catenin signaling.Experimental models of hepatocellular carcinomac-Myc and transforming growth factor α enhance the development of hepatic lesions due to mutant β-catenin in transgenic miceBeta-catenin signaling, liver regeneration and hepatocellular cancer: sorting the good from the bad.Histone Demethylases in Colon Cancer.Lysine-specific demethylase 1 (LSD1/KDM1A) contributes to colorectal tumorigenesis via activation of the Wnt/β-catenin pathway by down-regulating Dickkopf-1 (DKK1) [corrected].Effect of mutant β-catenin on liver growth homeostasis and hepatocarcinogenesis in transgenic miceDown-regulation of miR-129-5p inhibits growth and induces apoptosis in laryngeal squamous cell carcinoma by targeting APC.
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P2860
Liver-targeted disruption of Apc in mice activates beta-catenin signaling and leads to hepatocellular carcinomas
description
2004 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2004 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
article publié dans les Procee ...... f the United States of America
@fr
artículu científicu espublizáu en 2004
@ast
im Dezember 2004 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2004/12/07)
@sk
vědecký článek publikovaný v roce 2004
@cs
wetenschappelijk artikel (gepubliceerd op 2004/12/07)
@nl
наукова стаття, опублікована в грудні 2004
@uk
name
Liver-targeted disruption of A ...... s to hepatocellular carcinomas
@ast
Liver-targeted disruption of A ...... s to hepatocellular carcinomas
@en
Liver-targeted disruption of A ...... s to hepatocellular carcinomas
@nl
type
label
Liver-targeted disruption of A ...... s to hepatocellular carcinomas
@ast
Liver-targeted disruption of A ...... s to hepatocellular carcinomas
@en
Liver-targeted disruption of A ...... s to hepatocellular carcinomas
@nl
prefLabel
Liver-targeted disruption of A ...... s to hepatocellular carcinomas
@ast
Liver-targeted disruption of A ...... s to hepatocellular carcinomas
@en
Liver-targeted disruption of A ...... s to hepatocellular carcinomas
@nl
P2093
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P3181
P356
P1476
Liver-targeted disruption of A ...... s to hepatocellular carcinomas
@en
P2093
M. Giovannini
M. Niwa-Kawakita
T. Decaens
P2860
P304
17216–17221
P3181
P356
10.1073/PNAS.0404761101
P407
P577
2004-12-07T00:00:00Z