The p53 tumor suppressor gene: from molecular biology to clinical investigation.
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Tip60 is targeted to proteasome-mediated degradation by Mdm2 and accumulates after UV irradiationComparative analysis of cancer genes in the human and chimpanzee genomes.Constitutive activation of the Ras-Raf signaling pathway in metastatic melanoma is associated with poor prognosisModulation of p53 activity by IkappaBalpha: evidence suggesting a common phylogeny between NF-kappaB and p53 transcription factors.An Omics Perspective on Molecular Biomarkers for Diagnosis, Prognosis, and Therapeutics of CholangiocarcinomaThe important molecular markers on chromosome 17 and their clinical impact in breast cancerThe laminin response in inflammatory bowel disease: protection or malignancy?p53 Proteoforms and Intrinsic Disorder: An Illustration of the Protein Structure-Function Continuum ConceptMolecular predictors of survival after adjuvant chemotherapy for colon cancerLiver-targeted disruption of Apc in mice activates beta-catenin signaling and leads to hepatocellular carcinomasMetaplastic breast cancer: histologic characteristics, prognostic factors and systemic treatment strategies.Characterization of 9-nitrocamptothecin liposomes: anticancer properties and mechanisms on hepatocellular carcinoma in vitro and in vivo.Predictive and prognostic angiogenic markers in a gynecologic oncology group phase II trial of bevacizumab in recurrent and persistent ovarian or peritoneal cancer.Mutant p53-associated myosin-X upregulation promotes breast cancer invasion and metastasis.ING proteins as potential anticancer drug targets.Mutant p53 drives metastasis and overcomes growth arrest/senescence in pancreatic cancerAllelotyping identification of genomic alterations in rectal chromosomally unstable tumors without preoperative treatment.TESTIN suppresses tumor growth and invasion via manipulating cell cycle progression in endometrial carcinoma.Inhibition of NAD(P)H:quinone oxidoreductase 1 activity and induction of p53 degradation by the natural phenolic compound curcumin.Dysregulation of apoptotic signaling in cancer: molecular mechanisms and therapeutic opportunitiesProteomic analysis of chikungunya virus infected microgial cells.P53 hot-spot mutants are resistant to ubiquitin-independent degradation by increased binding to NAD(P)H:quinone oxidoreductase 1Stabilization of p53 by CP-31398 inhibits ubiquitination without altering phosphorylation at serine 15 or 20 or MDM2 binding.Clonality analysis of neuroendocrine cells in gastric adenocarcinoma.TP53 status and response to treatment in breast cancersThe role of p53 in the immunobiology of cutaneous squamous cell carcinoma.MIF family members cooperatively inhibit p53 expression and activityCo-mutation of p53, K-ras genes and accumulation of p53 protein and its correlation to clinicopathological features in rectal cancerGlucocorticoid receptor activation inhibits p53-induced apoptosis of MCF10Amyc cells via induction of protein kinase Cε.Micronuclei to detect in vivo chemotherapy damage in a p53 mutated solid tumour.Discovery of novel tumor suppressor p53 response elements using information theory.p53-targeted LSD1 functions in repression of chromatin structure and transcription in vivoDeletion of chromosome 17 as a novel cytogenetic finding in chronic neutrophilic leukemia: A case report.Correlation of p53 over-expression and alteration in p53 gene detected by polymerase chain reaction-single strand conformation polymorphism in adenocarcinoma of gastric cancer patients from IndiaGenetic polymorphisms and endometrial cancer risk.Multistage vectored siRNA targeting ataxia-telangiectasia mutated for breast cancer therapy.Serum p53 Antibody Is Not Associated with p53 Immunoreactivity in Patients with Pancreatobiliary Cancers.Reviewing the current classification of inhibitor of growth family proteins.5-FU targets rpL3 to induce mitochondrial apoptosis via cystathionine-β-synthase in colon cancer cells lacking p53.Chemotherapeutic potential of curcumin-bearing microcells against hepatocellular carcinoma in model animals.
P2860
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P2860
The p53 tumor suppressor gene: from molecular biology to clinical investigation.
description
2000 nî lūn-bûn
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2000 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2000 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2000年の論文
@ja
2000年論文
@yue
2000年論文
@zh-hant
2000年論文
@zh-hk
2000年論文
@zh-mo
2000年論文
@zh-tw
2000年论文
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name
The p53 tumor suppressor gene: from molecular biology to clinical investigation.
@ast
The p53 tumor suppressor gene: from molecular biology to clinical investigation.
@en
type
label
The p53 tumor suppressor gene: from molecular biology to clinical investigation.
@ast
The p53 tumor suppressor gene: from molecular biology to clinical investigation.
@en
prefLabel
The p53 tumor suppressor gene: from molecular biology to clinical investigation.
@ast
The p53 tumor suppressor gene: from molecular biology to clinical investigation.
@en
P1476
The p53 tumor suppressor gene: from molecular biology to clinical investigation
@en
P2093
P304
121-37; discussion 137-9
P356
10.1111/J.1749-6632.2000.TB06705.X
P407
P577
2000-06-01T00:00:00Z