Interaction of Shc with Grb2 regulates association of Grb2 with mSOS
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Characterization of RasGRP2, a plasma membrane-targeted, dual specificity Ras/Rap exchange factorThe role of a lymphoid-restricted, Grb2-like SH3-SH2-SH3 protein in T cell receptor signalingCripto enhances the tyrosine phosphorylation of Shc and activates mitogen-activated protein kinase (MAPK) in mammary epithelial cellsThe Grb2-mSos1 complex binds phosphopeptides with higher affinity than Grb2Epidermal growth factor receptor and the adaptor protein p52Shc are specific substrates of T-cell protein tyrosine phosphatase.Tandem SH2 binding sites mediate the RasGAP-RhoGAP interaction: a conformational mechanism for SH3 domain regulationThe heterotrimeric G q protein-coupled angiotensin II receptor activates p21 ras via the tyrosine kinase-Shc-Grb2-Sos pathway in cardiac myocytesTight association of GRB2 with receptor protein-tyrosine phosphatase alpha is mediated by the SH2 and C-terminal SH3 domainsThe 145-kDa protein induced to associate with Shc by multiple cytokines is an inositol tetraphosphate and phosphatidylinositol 3,4,5-triphosphate 5-phosphataseSLAP, a dimeric adapter protein, plays a functional role in T cell receptor signalingTyrosine phosphorylation mapping of the epidermal growth factor receptor signaling pathwayShcB and ShcC activation by the Trk family of receptor tyrosine kinasesT cell activation through the CD43 molecule leads to Vav tyrosine phosphorylation and mitogen-activated protein kinase pathway activationGrb2 forms an inducible protein complex with CD28 through a Src homology 3 domain-proline interactionRoles of Lck, Syk and ZAP-70 tyrosine kinases in TCR-mediated phosphorylation of the adapter protein ShcTyrosine phosphorylation of ACK in response to temperature shift-down, hyperosmotic shock, and epidermal growth factor stimulationFunctional importance of Shc tyrosine 317 on insulin signaling in Rat1 fibroblasts expressing insulin receptorsSteel factor induces tyrosine phosphorylation of CRKL and binding of CRKL to a complex containing c-kit, phosphatidylinositol 3-kinase, and p120(CBL)ShcA tyrosine phosphorylation sites can replace ShcA binding in signalling by middle T-antigenThe PTB domain of ShcA couples receptor activation to the cytoskeletal regulator IQGAP1Evidence for a physical association between the Shc-PTB domain and the beta c chain of the granulocyte-macrophage colony-stimulating factor receptorShc interaction with Src homology 2 domain containing inositol phosphatase (SHIP) in vivo requires the Shc-phosphotyrosine binding domain and two specific phosphotyrosines on SHIPEvidence for a role for the phosphotyrosine-binding domain of Shc in interleukin 2 signalingShc contains two Grb2 binding sites needed for efficient formation of complexes with SOS in B lymphocytesAssociation of p59(fyn) with the T lymphocyte costimulatory receptor CD2. Binding of the Fyn Src homology (SH) 3 domain is regulated by the Fyn SH2 domain.Association between receptor protein-tyrosine phosphatase RPTPalpha and the Grb2 adaptor. Dual Src homology (SH) 2/SH3 domain requirement and functional consequences.Role of the Lck Src homology 2 and 3 domains in protein tyrosine phosphorylation.CD16-mediated p21ras activation is associated with Shc and p36 tyrosine phosphorylation and their binding with Grb2 in human natural killer cells.The Grb2 adaptor.ShcA regulates thymocyte proliferation through specific transcription factors and a c-Abl-dependent signaling axis.Evidence for a requirement for both phospholipid and phosphotyrosine binding via the Shc phosphotyrosine-binding domain in vivoLymphocyte antigen receptor signal integration and regulation by the SHC adaptor.Signal transduction in T lymphocytes using a conditional allele of SosGrowth factor-independent proliferation of erythroid cells infected with Friend spleen focus-forming virus is protein kinase C dependent but does not require Ras-GTP.Genetic evidence for Shc requirement in TCR-induced c-Rel nuclear translocation and IL-2 expression.Identification of K-ras as the major regulator for cytokine-dependent Akt activation in erythroid progenitors in vivo.Anti-angiogenic tyrosine kinase inhibitors: what is their mechanism of action?Comparative proteomic profiling of mammalian cell lysates using phosphopeptide microarrays.Kinetic perspectives of T cell antigen receptor signaling. A two-tier model for T cell full activation.Identification of a novel pathway important for proliferation and differentiation of primary erythroid progenitors.
P2860
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P2860
Interaction of Shc with Grb2 regulates association of Grb2 with mSOS
description
1995 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
1995 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 1995
@ast
im Februar 1995 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 1995/02/01)
@sk
vědecký článek publikovaný v roce 1995
@cs
wetenschappelijk artikel (gepubliceerd op 1995/02/01)
@nl
наукова стаття, опублікована в лютому 1995
@uk
مقالة علمية (نشرت في فبراير 1995)
@ar
name
Interaction of Shc with Grb2 regulates association of Grb2 with mSOS
@ast
Interaction of Shc with Grb2 regulates association of Grb2 with mSOS
@en
Interaction of Shc with Grb2 regulates association of Grb2 with mSOS
@nl
type
label
Interaction of Shc with Grb2 regulates association of Grb2 with mSOS
@ast
Interaction of Shc with Grb2 regulates association of Grb2 with mSOS
@en
Interaction of Shc with Grb2 regulates association of Grb2 with mSOS
@nl
prefLabel
Interaction of Shc with Grb2 regulates association of Grb2 with mSOS
@ast
Interaction of Shc with Grb2 regulates association of Grb2 with mSOS
@en
Interaction of Shc with Grb2 regulates association of Grb2 with mSOS
@nl
P2093
P2860
P356
P1476
Interaction of Shc with Grb2 regulates association of Grb2 with mSOS
@en
P2093
K S Ravichandran
S E Shoelson
S J Burakoff
P2860
P304
P356
10.1128/MCB.15.2.593
P407
P50
P577
1995-02-01T00:00:00Z