Cholesterol esterification by ACAT2 is essential for efficient intestinal cholesterol absorption: evidence from thoracic lymph duct cannulation
about
Lipidomic and spatio-temporal imaging of fat by mass spectrometry in mice duodenum during lipid digestionTG-interacting factor 1 acts as a transcriptional repressor of sterol O-acyltransferase 2.Acute sterol o-acyltransferase 2 (SOAT2) knockdown rapidly mobilizes hepatic cholesterol for fecal excretion.Hepatic entrapment of esterified cholesterol drives continual expansion of whole body sterol pool in lysosomal acid lipase-deficient miceCholesterol esters (CE) derived from hepatic sterol O-acyltransferase 2 (SOAT2) are associated with more atherosclerosis than CE from intestinal SOAT2Tissue-specific knockouts of ACAT2 reveal that intestinal depletion is sufficient to prevent diet-induced cholesterol accumulation in the liver and blood.Intestine-specific MTP and global ACAT2 deficiency lowers acute cholesterol absorption with chylomicrons and HDLsEzetimibe blocks the internalization of NPC1L1 and cholesterol in mouse small intestine.Sterol O-Acyltransferase 2 Contributes to the Yolk Cholesterol Trafficking during Zebrafish EmbryogenesisCholesteryl ester accumulation and accelerated cholesterol absorption in intestine-specific hormone sensitive lipase-null miceACAT2 and ABCG5/G8 are both required for efficient cholesterol absorption in mice: evidence from thoracic lymph duct cannulation.Novel role of a triglyceride-synthesizing enzyme: DGAT1 at the crossroad between triglyceride and cholesterol metabolism.Sterol O-Acyltransferase 2-Driven Cholesterol Esterification Opposes Liver X Receptor-Stimulated Fecal Neutral Sterol Loss.Ezetimibe markedly attenuates hepatic cholesterol accumulation and improves liver function in the lysosomal acid lipase-deficient mouse, a model for cholesteryl ester storage disease.Inhibition of cholesterol absorption: targeting the intestine.Intestinal nuclear receptors in HDL cholesterol metabolism.Quantitation of the rates of hepatic and intestinal cholesterol synthesis in lysosomal acid lipase-deficient mice before and during treatment with ezetimibe.Impact of loss of SOAT2 function on disease progression in the lysosomal acid lipase-deficient mouse.Blackcurrant anthocyanins stimulated cholesterol transport via post-transcriptional induction of LDL receptor in Caco-2 cells.Molecular Pathways Underlying Cholesterol Homeostasis.ABCG5 and ABCG8: more than a defense against xenosterolsUpdate on the Benefits and Mechanisms of Action of the Bioactive Vegetal Alkaloid Berberine on Lipid Metabolism and Homeostasis
P2860
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P2860
Cholesterol esterification by ACAT2 is essential for efficient intestinal cholesterol absorption: evidence from thoracic lymph duct cannulation
description
2012 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2012 թվականի հունվարին հրատարակված գիտական հոդված
@hy
artikull shkencor
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artículu científicu espublizáu en 2012
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im Januar 2012 veröffentlichter wissenschaftlicher Artikel
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scientific journal article
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wetenschappelijk artikel
@nl
наукова стаття, опублікована в січні 2012
@uk
مقالة علمية (نشرت عام 2012)
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name
Cholesterol esterification by ...... horacic lymph duct cannulation
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Cholesterol esterification by ...... horacic lymph duct cannulation
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Cholesterol esterification by ...... horacic lymph duct cannulation
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type
label
Cholesterol esterification by ...... horacic lymph duct cannulation
@ast
Cholesterol esterification by ...... horacic lymph duct cannulation
@en
Cholesterol esterification by ...... horacic lymph duct cannulation
@nl
prefLabel
Cholesterol esterification by ...... horacic lymph duct cannulation
@ast
Cholesterol esterification by ...... horacic lymph duct cannulation
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Cholesterol esterification by ...... horacic lymph duct cannulation
@nl
P2093
P2860
P356
P1476
Cholesterol esterification by ...... horacic lymph duct cannulation
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P2093
Janet K. Sawyer
Kathryn L. Kelley
Lawrence L. Rudel
Matthew A. Davis
Tam M. Nguyen
P2860
P304
P356
10.1194/JLR.M018820
P577
2012-01-01T00:00:00Z