Targeted deletion of a cis-regulatory region reveals differential gene dosage requirements for Pdx1 in foregut organ differentiation and pancreas formation.
about
Stomach development, stem cells and diseasePancreatic ductal cells in development, regeneration, and neoplasiaTranscription factor regulation of pancreatic organogenesis, differentiation and maturationvon Hippel-Lindau gene disruption in mouse pancreatic progenitors and its consequences on endocrine differentiation in vivo: importance of HIF1-α and VEGF-A upregulationPcif1 modulates Pdx1 protein stability and pancreatic β cell function and survival in miceArx is required for normal enteroendocrine cell development in mice and humansSOX9 is required for maintenance of the pancreatic progenitor cell poolA dosage-dependent requirement for Sox9 in pancreatic endocrine cell formationInsm1 promotes endocrine cell differentiation by modulating the expression of a network of genes that includes Neurog3 and Ripply3Maternal deprivation alters epithelial secretory cell lineages in rat duodenum: role of CRF-related peptidesThe zinc-finger factor Insm1 (IA-1) is essential for the development of pancreatic beta cells and intestinal endocrine cellsRB regulates pancreas development by stabilizing Pdx1Early pancreatic development requires the vertebrate Suppressor of Hairless (RBPJ) in the PTF1 bHLH complexGenomic organisation of the seven ParaHox genes of coelacanthsA feat of metabolic proportions: Pdx1 orchestrates islet development and function in the maintenance of glucose homeostasis.Functional evaluation of ES cell-derived endodermal populations reveals differences between Nodal and Activin A-guided differentiation.β-Cell regeneration mediated by human bone marrow mesenchymal stem cells.A map of open chromatin in human pancreatic islets.A novel hypomorphic PDX1 mutation responsible for permanent neonatal diabetes with subclinical exocrine deficiencyFoxa2 and Pdx1 cooperatively regulate postnatal maturation of pancreatic β-cellsRecessive mutations in the INS gene result in neonatal diabetes through reduced insulin biosynthesis.Requirement for Pdx1 in specification of latent endocrine progenitors in zebrafish.Pancreatic stem/progenitor cells for the treatment of diabetes.Transcriptional regulation of α-cell differentiation.A fate map of the murine pancreas buds reveals a multipotent ventral foregut organ progenitor.Dynamic regulation of Pdx1 enhancers by Foxa1 and Foxa2 is essential for pancreas development.Sox9: a master regulator of the pancreatic program.Context-specific α- to-β-cell reprogramming by forced Pdx1 expression.Nkx2.2 repressor complex regulates islet β-cell specification and prevents β-to-α-cell reprogramming.TEAD and YAP regulate the enhancer network of human embryonic pancreatic progenitors.FGF10 signaling controls stomach morphogenesis.Genetic tracing of Nav1.8-expressing vagal afferents in the mouse.Ptf1a binds to and activates area III, a highly conserved region of the Pdx1 promoter that mediates early pancreas-wide Pdx1 expression.Tshz1 Regulates Pancreatic β-Cell Maturation.Four and a Half LIM Domains 1b (Fhl1b) Is Essential for Regulating the Liver versus Pancreas Fate Decision and for β-Cell RegenerationNegative regulation of pancreatic and duodenal homeobox-1 by somatostatin receptor subtype 5.The Chromatin Modifier MSK1/2 Suppresses Endocrine Cell Fates during Mouse Pancreatic Development.Inactivating the permanent neonatal diabetes gene Mnx1 switches insulin-producing β-cells to a δ-like fate and reveals a facultative proliferative capacity in aged β-cells.A distal intergenic region controls pancreatic endocrine differentiation by acting as a transcriptional enhancer and as a polycomb response element.REST represses a subset of the pancreatic endocrine differentiation program.
P2860
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P2860
Targeted deletion of a cis-regulatory region reveals differential gene dosage requirements for Pdx1 in foregut organ differentiation and pancreas formation.
description
2006 nî lūn-bûn
@nan
2006 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2006 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
name
Targeted deletion of a cis-reg ...... tiation and pancreas formation
@nl
Targeted deletion of a cis-reg ...... iation and pancreas formation.
@ast
Targeted deletion of a cis-reg ...... iation and pancreas formation.
@en
type
label
Targeted deletion of a cis-reg ...... tiation and pancreas formation
@nl
Targeted deletion of a cis-reg ...... iation and pancreas formation.
@ast
Targeted deletion of a cis-reg ...... iation and pancreas formation.
@en
prefLabel
Targeted deletion of a cis-reg ...... tiation and pancreas formation
@nl
Targeted deletion of a cis-reg ...... iation and pancreas formation.
@ast
Targeted deletion of a cis-reg ...... iation and pancreas formation.
@en
P2093
P2860
P356
P1433
P1476
Targeted deletion of a cis-reg ...... iation and pancreas formation.
@en
P2093
Christopher V E Wright
Daniel F Boyer
Masakazu Shiota
Maureen Gannon
Michael Ray
Roland W Stein
Shuko Fujitani
Yoshio Fujitani
Yoshiya Kawaguchi
P2860
P304
P356
10.1101/GAD.1360106
P577
2006-01-01T00:00:00Z