Hormonal regulation of an islet-specific enhancer in the pancreatic homeobox gene STF-1
about
Diabetes, defective pancreatic morphogenesis, and abnormal enteroendocrine differentiation in BETA2/neuroD-deficient miceConserved sequences in a tissue-specific regulatory region of the pdx-1 gene mediate transcription in Pancreatic beta cells: role for hepatocyte nuclear factor 3 beta and Pax6Novel transcriptional potentiation of BETA2/NeuroD on the secretin gene promoter by the DNA-binding protein Finb/RREB-1.Genes involved in pancreatic islet cell rejuvenationAutoregulation and maturity onset diabetes of the young transcription factors control the human PAX4 promoterDevelopment of diabetes mellitus in aging transgenic mice following suppression of pancreatic homeoprotein IDX-1Pcif1 modulates Pdx1 protein stability and pancreatic β cell function and survival in miceNeurogenin and NeuroD direct transcriptional targets and their regulatory enhancersThe forkhead transcription factor Foxo1 links insulin signaling to Pdx1 regulation of pancreatic beta cell growthTargeted deletion of a cis-regulatory region reveals differential gene dosage requirements for Pdx1 in foregut organ differentiation and pancreas formation.Foxa3 (HNF-3gamma) binds to and activates the rat proglucagon gene promoter but is not essential for proglucagon gene expressionPdx1 and BETA2/NeuroD1 participate in a transcriptional complex that mediates short-range DNA looping at the insulin gene.Altered expression of insulins I and II and their mRNAs in the islets of Langerhans in dexamethasone-induced diabetic rats.Glucose regulates steady-state levels of PDX1 via the reciprocal actions of GSK3 and AKT kinasesFoxa2 and Pdx1 cooperatively regulate postnatal maturation of pancreatic β-cellsMixed lineage kinase-3 stabilizes and functionally cooperates with TRIBBLES-3 to compromise mitochondrial integrity in cytokine-induced death of pancreatic beta cellsPancreatic development and adult diabetes.Dynamic regulation of Pdx1 enhancers by Foxa1 and Foxa2 is essential for pancreas development.Transcription factors in islet development and physiology: role of PDX-1 in beta-cell function.Twists and turns in the development and maintenance of the mammalian small intestine epithelium.Hepatocyte nuclear factor 3beta is involved in pancreatic beta-cell-specific transcription of the pdx-1 gene.Fetal PGC-1α overexpression programs adult pancreatic β-cell dysfunctionGenomic sequencing of key genes in mouse pancreatic cancer cells.Foxa2 regulates multiple pathways of insulin secretion.A newly identified mutation in an IPF1 binding site of the insulin gene promoter may predispose to type 2 diabetes mellitus.Defining a Novel Role for the PDX1 Transcription Factor in Islet β Cell Maturation and Proliferation During Weaning.Functional conservation of regulatory elements in the pdx-1 gene: PDX-1 and hepatocyte nuclear factor 3beta transcription factors mediate beta-cell-specific expression.Insulin promoter factor-1 gene mutation linked to early-onset type 2 diabetes mellitus directs expression of a dominant negative isoprotein.The basic helix-loop-helix transcription factor NeuroD1 facilitates interaction of Sp1 with the secretin gene enhancer.Regulation of pancreas duodenum homeobox-1 expression by early growth response-1.Glucocorticoids suppress beta-cell development and induce hepatic metaplasia in embryonic pancreasDistinct gene expression programs function in progenitor and mature islet cells.Upstream stimulatory factor regulates Pdx-1 gene expression in differentiated pancreatic beta-cells.Genetically Targeted Dipeptidyl Peptidase-4 Inhibitor Use in a Patient with a Novel Mutation of MODY type 4.Glucocorticoids impair fetal beta-cell development in rats.Involvement of thioredoxin-interacting protein (TXNIP) in glucocorticoid-mediated beta cell death.Pancreatic beta cell-specific transcription of the pdx-1 gene. The role of conserved upstream control regions and their hepatic nuclear factor 3beta sites.Identification of transcriptional targets during pancreatic growth after partial pancreatectomy and exendin-4 treatment.New functional aspects of the neuroendocrine marker secretagogin based on the characterization of its rat homolog
P2860
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P2860
Hormonal regulation of an islet-specific enhancer in the pancreatic homeobox gene STF-1
description
1997 nî lūn-bûn
@nan
1997 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
1997 թվականի մայիսին հրատարակված գիտական հոդված
@hy
1997年の論文
@ja
1997年論文
@yue
1997年論文
@zh-hant
1997年論文
@zh-hk
1997年論文
@zh-mo
1997年論文
@zh-tw
1997年论文
@wuu
name
Hormonal regulation of an islet-specific enhancer in the pancreatic homeobox gene STF-1
@ast
Hormonal regulation of an islet-specific enhancer in the pancreatic homeobox gene STF-1
@en
Hormonal regulation of an islet-specific enhancer in the pancreatic homeobox gene STF-1
@nl
type
label
Hormonal regulation of an islet-specific enhancer in the pancreatic homeobox gene STF-1
@ast
Hormonal regulation of an islet-specific enhancer in the pancreatic homeobox gene STF-1
@en
Hormonal regulation of an islet-specific enhancer in the pancreatic homeobox gene STF-1
@nl
prefLabel
Hormonal regulation of an islet-specific enhancer in the pancreatic homeobox gene STF-1
@ast
Hormonal regulation of an islet-specific enhancer in the pancreatic homeobox gene STF-1
@en
Hormonal regulation of an islet-specific enhancer in the pancreatic homeobox gene STF-1
@nl
P2093
P2860
P356
P1476
Hormonal regulation of an islet-specific enhancer in the pancreatic homeobox gene STF-1
@en
P2093
P2860
P304
P356
10.1128/MCB.17.5.2598
P407
P577
1997-05-01T00:00:00Z