Human alpha-L-iduronidase: cDNA isolation and expression
about
Sanfilippo syndrome: causes, consequences, and treatmentsHuman α-l-iduronidase uses its own N -glycan as a substrate-binding and catalytic moduleMucopolysaccharidosis type I: characterization of novel mutations affecting alpha-L-iduronidase activityIdentification of mutations in the alpha-L-iduronidase gene (IDUA) that cause Hurler and Scheie syndromesMucopolysaccharidosis type I: identification of novel mutations that cause Hurler/Scheie syndrome in Chinese families.Comparison of Endovascular and Intraventricular Gene Therapy With Adeno-Associated Virus-α-L-Iduronidase for Hurler DiseaseThe human metabolic reconstruction Recon 1 directs hypotheses of novel human metabolic functionsSafe, efficient, and reproducible gene therapy of the brain in the dog models of Sanfilippo and Hurler syndromes.A novel p.E276K IDUA mutation decreasing α-L-iduronidase activity causes mucopolysaccharidosis type I.When cells stop making sense: effects of nonsense codons on RNA metabolism in vertebrate cells.Molecular analysis of mucopolysaccharidosis type I in Tunisia: identification of novel mutation and eight Novel polymorphisms.Mucopolysaccharidosis type I: molecular characteristics of two novel alpha-L-iduronidase mutations in Tunisian patientsMolecular analysis of Hurler syndrome in Druze and Muslim Arab patients in Israel: multiple allelic mutations of the IDUA gene in a small geographic area.Molecular genetic defect underlying alpha-L-iduronidase pseudodeficiency.IgG-enzyme fusion protein: pharmacokinetics and anti-drug antibody response in rhesus monkeys.Carbohydrate structures of recombinant human alpha-L-iduronidase secreted by Chinese hamster ovary cells.Efficient IDUA Gene Mutation Detection with Combined Use of dHPLC and Dried Blood Samples.AGT-181: expression in CHO cells and pharmacokinetics, safety, and plasma iduronidase enzyme activity in Rhesus monkeys.Reprogramming erythroid cells for lysosomal enzyme production leads to visceral and CNS cross-correction in mice with Hurler syndrome.Biopharmaceutical drug targeting to the brain.Long-term in vitro correction of alpha-L-iduronidase deficiency (Hurler syndrome) in human bone marrow.Human alpha-L-iduronidase. Catalytic properties and an integrated role in the lysosomal degradation of heparan sulphate.Identification of glu-277 as the catalytic nucleophile of Thermoanaerobacterium saccharolyticum beta-xylosidase using electrospray MS.Adeno-associated viral gene therapy for mucopolysaccharidoses exhibiting neurodegeneration.Recombinant alpha-L-iduronidase: characterization of the purified enzyme and correction of mucopolysaccharidosis type I fibroblasts.In vitro gene therapy of mucopolysaccharidosis type I by lentiviral vectors.p.X654R IDUA variant among Thai individuals with intermediate mucopolysaccharidosis type I and its residual activity as demonstrated in COS-7 cells.An Integrated Computational Framework to Assess the Mutational Landscape of α-L-Iduronidase IDUA Gene.IDUA hydrolyses Heparan sulfate chain(1)IDUA hydrolyses Heparan sulfate chain(6)IDUA) hydrolyses the unsulfated alpha-L-iduronosidic link in DSNovel splice site IDUA gene mutation in Tunisian pedigrees with hurler syndrome.New nucleotide sequence data on the EMBL File Server
P2860
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P2860
Human alpha-L-iduronidase: cDNA isolation and expression
description
1991 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
1991 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
article publié dans les Procee ...... f the United States of America
@fr
artículu científicu espublizáu en 1991
@ast
im November 1991 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 1991/11/01)
@sk
vědecký článek publikovaný v roce 1991
@cs
wetenschappelijk artikel (gepubliceerd op 1991/11/01)
@nl
наукова стаття, опублікована в листопаді 1991
@uk
name
Human alpha-L-iduronidase: cDNA isolation and expression
@ast
Human alpha-L-iduronidase: cDNA isolation and expression
@en
Human alpha-L-iduronidase: cDNA isolation and expression
@nl
type
label
Human alpha-L-iduronidase: cDNA isolation and expression
@ast
Human alpha-L-iduronidase: cDNA isolation and expression
@en
Human alpha-L-iduronidase: cDNA isolation and expression
@nl
prefLabel
Human alpha-L-iduronidase: cDNA isolation and expression
@ast
Human alpha-L-iduronidase: cDNA isolation and expression
@en
Human alpha-L-iduronidase: cDNA isolation and expression
@nl
P2093
P2860
P356
P1476
Human alpha-L-iduronidase: cDNA isolation and expression
@en
P2093
A M Orsborn
J J Hopwood
P R Clements
P V Nelson
P2860
P304
P356
10.1073/PNAS.88.21.9695
P407
P577
1991-11-01T00:00:00Z