Syk-dependent phosphorylation of Shc. A potential link between FcepsilonRI and the Ras/mitogen-activated protein kinase signaling pathway through SOS and Grb2 - Wikidata - wikimedia - TriplyDB

Syk-dependent phosphorylation of Shc. A potential link between FcepsilonRI and the Ras/mitogen-activated protein kinase signaling pathway through SOS and Grb2

Syk-dependent phosphorylation of Shc. A potential link between FcepsilonRI and the Ras/mitogen-activated protein kinase signaling pathway through SOS and Grb2

http://www.wikidata.org/entity/Q28610834

about

Protein kinase C-delta is a negative regulator of antigen-induced mast cell degranulation An essential role for RasGRP1 in mast cell function and IgE-mediated allergic response Mast cell activation: a complex interplay of positive and negative signaling pathways RabGEF1 is a negative regulator of mast cell activation and skin inflammation Fer kinase is required for sustained p38 kinase activation and maximal chemotaxis of activated mast cells Shc contains two Grb2 binding sites needed for efficient formation of complexes with SOS in B lymphocytes Tyrosine phosphorylation of the vav proto-oncogene product links FcepsilonRI to the Rac1-JNK pathway Regulation of the pp72syk protein tyrosine kinase by platelet integrin alpha IIb beta 3 TOM1L1 is a Lyn substrate involved in FcepsilonRI signaling in mast cells.Involvement of Fc receptors in disorders of the central nervous system.Independent and cooperative roles of adaptor molecules in proximal signaling during FcepsilonRI-mediated mast cell activation Adapters in the organization of mast cell signaling.The era of the immunoglobulin A Fc receptor FcαRI; its function and potential as target in disease.The high-affinity IgE receptor (FcepsilonRI): a critical regulator of airway smooth muscle cells?Impaired degranulation but enhanced cytokine production after Fc epsilonRI stimulation of diacylglycerol kinase zeta-deficient mast cells.Regulation of the mast cell response to the type 1 Fc epsilon receptor.Tetraspanin CD151 Is a Negative Regulator of FcεRI-Mediated Mast Cell Activation Quantitative time-resolved phosphoproteomic analysis of mast cell signaling.FcγRIIB-Independent Mechanisms Controlling Membrane Localization of the Inhibitory Phosphatase SHIP in Human B Cells.The tyrosine kinase Syk promotes phagocytosis of Francisella through the activation of Erk Rubiae Radix suppresses the activation of mast cells through the inhibition of Syk kinase for anti-allergic activity.Transcriptional regulation of the cyclooxygenase-2 gene in activated mast cells.Fcgamma receptor-mediated mitogen-activated protein kinase activation in monocytes is independent of Ras.Involvement of Ras in Bruton's tyrosine kinase-mediated JNK activation.VLA-4 integrin cross-linking on human monocytic THP-1 cells induces tissue factor expression by a mechanism involving mitogen-activated protein kinase.Destabilization of TNF-α mRNA by Rapamycin.Negative regulation of Fc epsilon RI-mediated degranulation by CD81.Piceatannol is an effective inhibitor of IgE-mediated secretion from human basophils but is neither selective for this receptor nor acts on syk kinase at concentrations where mediator release inhibition occurs.Differential regulation of mast cell cytokines by both dexamethasone and the p38 mitogen-activated protein kinase (MAPK) inhibitor SB203580.In-vitro and in-vivo anti-allergic actions of Arecae semen.Mechanisms of the action of adenine on anti-allergic effects in mast cells.Recruitment of GRB2:SOS to p-5Y-LAT Phosphorylation of SHC by SYK kinase Disruption of Raf-1/heat shock protein 90 complex and Raf signaling by dexamethasone in mast cells.

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Syk-dependent phosphorylation of Shc. A potential link between FcepsilonRI and the Ras/mitogen-activated protein kinase signaling pathway through SOS and Grb2

http://www.wikidata.org/entity/Q28610834

description

1996 թուականի Յուլիսին հրատարակուած գիտական յօդուած

@hyw

1996 թվականի հուլիսին հրատարակված գիտական հոդված

@hy

article publié dans la revue scientifique Journal of Biological Chemistry

@fr

artículu científicu espublizáu en 1996

@ast

im Juli 1996 veröffentlichter wissenschaftlicher Artikel

@de

scientific journal article

@en

vedecký článok (publikovaný 1996/07/05)

@sk

vědecký článek publikovaný v roce 1996

@cs

wetenschappelijk artikel (gepubliceerd op 1996/07/05)

@nl

наукова стаття, опублікована в липні 1996

@uk

name

Syk-dependent phosphorylation ...... g pathway through SOS and Grb2

@ast

Syk-dependent phosphorylation ...... g pathway through SOS and Grb2

@en

Syk-dependent phosphorylation ...... g pathway through SOS and Grb2

@nl

type

label

Syk-dependent phosphorylation ...... g pathway through SOS and Grb2

@ast

Syk-dependent phosphorylation ...... g pathway through SOS and Grb2

@en

Syk-dependent phosphorylation ...... g pathway through SOS and Grb2

@nl

prefLabel

Syk-dependent phosphorylation ...... g pathway through SOS and Grb2

@ast

Syk-dependent phosphorylation ...... g pathway through SOS and Grb2

@en

Syk-dependent phosphorylation ...... g pathway through SOS and Grb2

@nl

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JBC.271.27.16268

P1433

Journal of Biological Chemistry

P1476

Syk-dependent phosphorylation ...... g pathway through SOS and Grb2

@en

P2093

A. M. Scharenberg

http://www.w3.org/2001/XMLSchema#string

B. Jabril-Cuenod

http://www.w3.org/2001/XMLSchema#string

C. Zhang

http://www.w3.org/2001/XMLSchema#string

J. P. Kinet

http://www.w3.org/2001/XMLSchema#string

M. A. Beaven

http://www.w3.org/2001/XMLSchema#string

R. Numerof

http://www.w3.org/2001/XMLSchema#string

R. Paolini

http://www.w3.org/2001/XMLSchema#string

P2860

The SH2 and SH3 domain-containing protein GRB2 links receptor tyrosine kinases to ras signaling

A novel transforming protein (SHC) with an SH2 domain is implicated in mitogenic signal transduction

Transphosphorylation as the mechanism by which the high-affinity receptor for IgE is phosphorylated upon aggregation

The function of GRB2 in linking the insulin receptor to Ras signaling pathways

The SH2 and SH3 domains of mammalian Grb2 couple the EGF receptor to the Ras activator mSos1

Association of Sos Ras exchange protein with Grb2 is implicated in tyrosine kinase signal transduction and transformation

Grb2 mediates the EGF-dependent activation of guanine nucleotide exchange on Ras

Association of the Shc and Grb2/Sem5 SH2-containing proteins is implicated in activation of the Ras pathway by tyrosine kinases

The SH3 domain-binding T cell tyrosyl phosphoprotein p120. Demonstration of its identity with the c-cbl protooncogene product and in vivo complexes with Fyn, Grb2, and phosphatidylinositol 3-kinase.

The protein product of the c-cbl protooncogene is phosphorylated after B cell receptor stimulation and binds the SH3 domain of Bruton's tyrosine kinase.

P304

16268–16272

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scholarly article

P356

10.1074/JBC.271.27.16268

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P407

P433

27

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P478

271

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P577

1996-07-05T00:00:00Z

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P5875

14538173

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P698

8663278

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P921

phosphorylation