The tyrosine kinase Syk promotes phagocytosis of Francisella through the activation of Erk
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MiR-155 induction by F. novicida but not the virulent F. tularensis results in SHIP down-regulation and enhanced pro-inflammatory cytokine responseICAM-1 suppresses tumor metastasis by inhibiting macrophage M2 polarization through blockade of efferocytosis.Adherence and uptake of Francisella into host cellsAkt and SHIP modulate Francisella escape from the phagosome and induction of the Fas-mediated death pathway.Host factors required for modulation of phagosome biogenesis and proliferation of Francisella tularensis within the cytosol.Fcgamma receptor cross-linking stimulates cell proliferation of macrophages via the ERK pathway.A mathematical model of CR3/TLR2 crosstalk in the context of Francisella tularensis infection.Adiponectin inhibits neutrophil phagocytosis of Escherichia coli by inhibition of PKB and ERK 1/2 MAPK signalling and Mac-1 activationThe francisella intracellular life cycle: toward molecular mechanisms of intracellular survival and proliferation.Role of mTOR downstream effector signaling molecules in Francisella tularensis internalization by murine macrophages.Inflammasome priming is similar for francisella species that differentially induce inflammasome activation.Francisella tularensis Catalase Restricts Immune Function by Impairing TRPM2 Channel Activity.Temporal transcriptional response during infection of type II alveolar epithelial cells with Francisella tularensis live vaccine strain (LVS) supports a general host suppression and bacterial uptake by macropinocytosis.Comparative phosphoproteomics reveals components of host cell invasion and post-transcriptional regulation during Francisella infection.Lipoprotein accumulation in macrophages via toll-like receptor-4-dependent fluid phase uptake.Mitogen-activated protein kinases (MAPKs) are modulated during Francisella tularensis infection, but inhibition of extracellular-signal-regulated kinases (ERKs) is of limited therapeutic benefitMonocyte/macrophage inflammatory response pathways to combat Francisella infection: possible therapeutic targets?Keyhole limpet hemocyanin induces innate immunity via Syk and Erk phosphorylation.Triggering Ras signalling by intracellular Francisella tularensis through recruitment of PKCα and βI to the SOS2/GrB2 complex is essential for bacterial proliferation in the cytosol.Effective host response to Francisella tularensis requires functional mast cells.Increased Resistance to Intradermal Francisella tularensis LVS Infection by Inactivation of the Sts Phosphatases.Exploitation of host cell biology and evasion of immunity by francisella tularensis.A novel immunomodulatory function of PHLPP1: inhibition of iNOS via attenuation of STAT1 ser727 phosphorylation in mouse macrophages.Dexmedetomidine attenuates acute lung injury induced by lipopolysaccharide in mouse through inhibition of MAPK pathway.Quantitative phosphoproteomics reveals involvement of multiple signaling pathways in early phagocytosis by the retinal pigmented epithelium.The Early Dendritic Cell Signaling Induced by Virulent Francisella tularensis Strain Occurs in Phases and Involves the Activation of Extracellular Signal-Regulated Kinases (ERKs) and p38 In the Later Stage.Francisella Subverts Innate Immune Signaling: Focus On PI3K/Akt.
P2860
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P2860
The tyrosine kinase Syk promotes phagocytosis of Francisella through the activation of Erk
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
2008年论文
@zh
2008年论文
@zh-cn
name
The tyrosine kinase Syk promot ...... through the activation of Erk
@en
type
label
The tyrosine kinase Syk promot ...... through the activation of Erk
@en
prefLabel
The tyrosine kinase Syk promot ...... through the activation of Erk
@en
P2093
P2860
P1433
P1476
The tyrosine kinase Syk promot ...... through the activation of Erk
@en
P2093
Jonathan P Butchar
Kishore V L Parsa
Murugesan V S Rajaram
Susheela Tridandapani
Thomas J Cremer
P2860
P304
P356
10.1016/J.MOLIMM.2008.01.011
P577
2008-03-04T00:00:00Z