MHC class II-associated invariant chain contains a sorting signal for endosomal compartments
about
CD74 interacts with APP and suppresses the production of AbetaDeficient peptide loading and MHC class II endosomal sorting in a human genetic immunodeficiency disease: the Chediak-Higashi syndromeMapping the HLA-DO/HLA-DM complex by FRET and mutagenesisNuclear and mitochondrial forms of human uracil-DNA glycosylase are encoded by the same geneMHC class I-related neonatal Fc receptor for IgG is functionally expressed in monocytes, intestinal macrophages, and dendritic cellsMajor histocompatibility complex class II-peptide complexes internalize using a clathrin- and dynamin-independent endocytosis pathwayHLA-DR associates with specific stress proteins and is retained in the endoplasmic reticulum in invariant chain negative cellsMajor histocompatibility complex class II-associated p41 invariant chain fragment is a strong inhibitor of lysosomal cathepsin LMapping functional regions in the lumenal domain of the class II-associated invariant chainThe role of major histocompatibility complex molecules in luteal functionThe Role of FcRn in Antigen PresentationMHC class II association with lipid rafts on the antigen presenting cell surfaceRoles for major histocompatibility complex glycosylation in immune functionSusceptibility to HLA-DM Protein Is Determined by a Dynamic Conformation of Major Histocompatibility Complex Class II Molecule Bound with PeptideAchieving stability through editing and chaperoning: regulation of MHC class II peptide binding and expressionDiffering processing requirements of four recombinant antigens containing a single defined T-cell epitope for presentation by major histocompatibility complex class IIThe p41 isoform of invariant chain is a chaperone for cathepsin LThe invariant chain is required for intracellular transport and function of major histocompatibility complex class II moleculesDefective major histocompatibility complex class II assembly, transport, peptide acquisition, and CD4+ T cell selection in mice lacking invariant chain expressionMHC class II antigen presentation pathway in murine tumours: tumour evasion from immunosurveillance?Direct transport of newly synthesized HLA-DR from the trans-Golgi network to major histocompatibility complex class II containing compartments (MIICS) demonstrated using a novel tyrosine-sulfated chimeraThe leucine-based sorting motifs in the cytoplasmic domain of the invariant chain are recognized by the clathrin adaptors AP1 and AP2 and their medium chainsStructure-activity relationship of the leucine-based sorting motifs in the cytosolic tail of the major histocompatibility complex-associated invariant chainA role for acidic residues in di-leucine motif-based targeting to the endocytic pathwayStructural features of the invariant chain fragment CLIP controlling rapid release from HLA-DR molecules and inhibition of peptide bindingEndosomal aspartic proteinases are required for invariant-chain processingA role for calnexin (IP90) in the assembly of class II MHC moleculesDirect vesicular transport of MHC class II molecules from lysosomal structures to the cell surfaceExpression of major histocompatibility complex class II molecules in HeLa cells promotes the recruitment of AP-1 Golgi-specific assembly proteins on Golgi membranesEditing of the HLA-DR-peptide repertoire by HLA-DMInvariant chain made in Escherichia coli has an exposed N-terminal segment that blocks antigen binding to HLA-DR1 and a trimeric C-terminal segment that binds empty HLA-DR1The impact of the non-classical MHC proteins HLA-DM and HLA-DO on loading of MHC class II moleculesIi-Key/MHC class II epitope hybrids: a strategy that enhances MHC class II epitope loading to create more potent peptide vaccines.Polarized expression of CD74 by gastric epithelial cells.Assembly of major histocompatibility complex class II subunits with invariant chain.Cytosolic N-terminal arginine-based signals together with a luminal signal target a type II membrane protein to the plant ER.Truncation of the class II beta-chain cytoplasmic domain influences the level of class II/invariant chain-derived peptide complexes.Evolution of the mammalian MHC: natural selection, recombination, and convergent evolution.Cytomegaloviral control of MHC class I function in the mouse.Phagocytic antigen processing and effects of microbial products on antigen processing and T-cell responses.
P2860
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P2860
MHC class II-associated invariant chain contains a sorting signal for endosomal compartments
description
1990 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
1990 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 1990
@ast
im November 1990 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 1990/11/16)
@sk
vědecký článek publikovaný v roce 1990
@cs
wetenschappelijk artikel (gepubliceerd op 1990/11/16)
@nl
наукова стаття, опублікована в листопаді 1990
@uk
مقالة علمية (نشرت في 16-11-1990)
@ar
name
MHC class II-associated invari ...... nal for endosomal compartments
@ast
MHC class II-associated invari ...... nal for endosomal compartments
@en
MHC class II-associated invari ...... nal for endosomal compartments
@nl
type
label
MHC class II-associated invari ...... nal for endosomal compartments
@ast
MHC class II-associated invari ...... nal for endosomal compartments
@en
MHC class II-associated invari ...... nal for endosomal compartments
@nl
prefLabel
MHC class II-associated invari ...... nal for endosomal compartments
@ast
MHC class II-associated invari ...... nal for endosomal compartments
@en
MHC class II-associated invari ...... nal for endosomal compartments
@nl
P1433
P1476
MHC class II-associated invari ...... nal for endosomal compartments
@en
P2093
B. Dobberstein
P304
P356
10.1016/0092-8674(90)90137-4
P407
P577
1990-11-16T00:00:00Z