Deficient peptide loading and MHC class II endosomal sorting in a human genetic immunodeficiency disease: the Chediak-Higashi syndrome
about
A unique region of RILP distinguishes it from its related proteins in its regulation of lysosomal morphology and interaction with Rab7 and Rab34Distinct protein sorting and localization to premelanosomes, melanosomes, and lysosomes in pigmented melanocytic cellsHigh-Throughput GoMiner, an 'industrial-strength' integrative gene ontology tool for interpretation of multiple-microarray experiments, with application to studies of Common Variable Immune Deficiency (CVID).Elevated oxidative membrane damage associated with genetic modifiers of Lyst-mutant phenotypesImpact of lysosome status on extracellular vesicle content and releaseA thiol proteinase inhibitor, E-64-d, corrects the abnormalities in concanavalin A cap formation and the lysosomal enzyme activity in leucocytes from patients with Chediak-Higashi syndrome by reversing the down-regulated protein kinase C activityNovel organization and properties of annexin 2-membrane complexes.EBAG9 tempers lymphocyte killing activity.Differences in Granule Morphology yet Equally Impaired Exocytosis among Cytotoxic T Cells and NK Cells from Chediak-Higashi Syndrome PatientsHuman pathogen subversion of antigen presentation.Dictyostelium LvsB mutants model the lysosomal defects associated with Chediak-Higashi syndrome.Analysis of the lysosomal storage disease Chediak-Higashi syndrome.Hermansky-Pudlak syndrome and related disorders of organelle formation.MicroRNA-mediated networks underlie immune response regulation in papillary thyroid carcinoma.Autoimmunity and the immunotherapy of cancer: targeting the "self" to destroy the "other".Novel Heterogenous CHS1 Mutations Identified in Five Japanese Patients with Chediak-Higashi SyndromeTranscriptome analysis of newt lens regeneration reveals distinct gradients in gene expression patterns.Chediak-Higashi Syndrome: a rare disorder of lysosomes and lysosome related organelles.Lysosomes and the plasma membrane: trypanosomes reveal a secret relationshipDefective CTLA-4 cycling pathway in Chediak-Higashi syndrome: a possible mechanism for deregulation of T lymphocyte activation.blue cheese mutations define a novel, conserved gene involved in progressive neural degeneration.Haplotype Association Mapping Identifies a Candidate Gene Region in Mice Infected With Staphylococcus aureusPrimary hemophagocytic syndromes point to a direct link between lymphocyte cytotoxicity and homeostasis.Functional dichotomy in natural killer cell signaling: Vav1-dependent and -independent mechanisms.The Sar1 GTPase coordinates biosynthetic cargo selection with endoplasmic reticulum export site assembly.Chediak-Higashi syndrome: Lysosomal trafficking regulator domains regulate exocytosis of lytic granules but not cytokine secretion by natural killer cells.Endothelial peroxisomal dysfunction and impaired pexophagy promotes oxidative damage in lipopolysaccharide-induced acute kidney injury.Small interfering RNA-mediated silencing of nicotinamide phosphoribosyltransferase (NAMPT) and lysosomal trafficking regulator (LYST) induce growth inhibition and apoptosis in human multiple myeloma cells: A preliminary study.Whole Genome Sequencing Identifies Novel Compound Heterozygous Lysosomal Trafficking Regulator Gene Mutations Associated with Autosomal Recessive Chediak-Higashi Syndrome.Defective lysosomal exocytosis and plasma membrane repair in Chediak-Higashi/beige cells.In the crosshairs: investigating lytic granules by high-resolution microscopy and electrophysiology.LYST affects lysosome size and quantity, but not trafficking or degradation through autophagy or endocytosis.LAMP-2-deficient human B cells exhibit altered MHC class II presentation of exogenous antigens.The BEACH Protein LRBA Promotes the Localization of the Heterotrimeric G-protein Golf to Olfactory Cilia.HIV-1 p55Gag encoded in the lysosome-associated membrane protein-1 as a DNA plasmid vaccine chimera is highly expressed, traffics to the major histocompatibility class II compartment, and elicits enhanced immune responses.LIP5 interacts with aquaporin 2 and facilitates its lysosomal degradation.Gene expression profiles during human CD4+ T cell differentiation.Physical, Functional and Genetic Interactions between the BEACH Domain Protein SPIRRIG and LIP5 and SKD1 and Its Role in Endosomal Trafficking to the Vacuole in Arabidopsis.Periodontitis in Chédiak-Higashi Syndrome: An Altered Immunoinflammatory Response.An actin cytoskeletal barrier inhibits lytic granule release from Natural Killer cells in Chediak-Higashi syndrome.
P2860
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P2860
Deficient peptide loading and MHC class II endosomal sorting in a human genetic immunodeficiency disease: the Chediak-Higashi syndrome
description
1998 nî lūn-bûn
@nan
1998 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
1998 թվականի հունիսին հրատարակված գիտական հոդված
@hy
1998年の論文
@ja
1998年論文
@yue
1998年論文
@zh-hant
1998年論文
@zh-hk
1998年論文
@zh-mo
1998年論文
@zh-tw
1998年论文
@wuu
name
Deficient peptide loading and ...... : the Chediak-Higashi syndrome
@ast
Deficient peptide loading and ...... : the Chediak-Higashi syndrome
@en
Deficient peptide loading and ...... : the Chediak-Higashi syndrome
@en-gb
Deficient peptide loading and ...... : the Chediak-Higashi syndrome
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type
label
Deficient peptide loading and ...... : the Chediak-Higashi syndrome
@ast
Deficient peptide loading and ...... : the Chediak-Higashi syndrome
@en
Deficient peptide loading and ...... : the Chediak-Higashi syndrome
@en-gb
Deficient peptide loading and ...... : the Chediak-Higashi syndrome
@nl
prefLabel
Deficient peptide loading and ...... : the Chediak-Higashi syndrome
@ast
Deficient peptide loading and ...... : the Chediak-Higashi syndrome
@en
Deficient peptide loading and ...... : the Chediak-Higashi syndrome
@en-gb
Deficient peptide loading and ...... : the Chediak-Higashi syndrome
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P2093
P2860
P50
P356
P1476
Deficient peptide loading and ...... : the Chediak-Higashi syndrome
@en
P2093
G de Saint-Basile
H Kropshofer
P2860
P304
P356
10.1083/JCB.141.5.1121
P407
P577
1998-06-01T00:00:00Z