Differential regulation of E2F transactivation by cyclin/cdk2 complexes
about
The decision to enter mitosis: feedback and redundancy in the mitotic entry networkDDB, a putative DNA repair protein, can function as a transcriptional partner of E2F1.Roscovitine, a specific inhibitor of cellular cyclin-dependent kinases, inhibits herpes simplex virus DNA synthesis in the presence of viral early proteinsAssociation of human CUL-1 and ubiquitin-conjugating enzyme CDC34 with the F-box protein p45(SKP2): evidence for evolutionary conservation in the subunit composition of the CDC34-SCF pathwayThe ETS protein MEF is regulated by phosphorylation-dependent proteolysis via the protein-ubiquitin ligase SCFSkp2.HIRA, the human homologue of yeast Hir1p and Hir2p, is a novel cyclin-cdk2 substrate whose expression blocks S-phase progressionThe consensus motif for phosphorylation by cyclin D1-Cdk4 is different from that for phosphorylation by cyclin A/E-Cdk2Inhibition of E2F-mediated transcription by p202E2F-4 and E2F-5, two members of the E2F family, are expressed in the early phases of the cell cycleGenetic characterization of a mammalian protein-protein interaction domain by using a yeast reverse two-hybrid systemStructural basis of DNA recognition by the heterodimeric cell cycle transcription factor E2F-DPExpression of NPAT, a novel substrate of cyclin E-CDK2, promotes S-phase entryCyclin A/CDK2 binds directly to E2F-1 and inhibits the DNA-binding activity of E2F-1/DP-1 by phosphorylationAnalysis of promoter binding by the E2F and pRB families in vivo: distinct E2F proteins mediate activation and repressionDP-2, a heterodimeric partner of E2F: identification and characterization of DP-2 proteins expressed in vivoThe subcellular localization of E2F-4 is cell-cycle dependentE2F activity is regulated by cell cycle-dependent changes in subcellular localizationInduction of S-phase entry by E2F transcription factors depends on their nuclear localizationSpecific regulation of E2F family members by cyclin-dependent kinasesFunctional interaction between DP-1 and p53E2F-4 switches from p130 to p107 and pRB in response to cell cycle reentryIn vivo structure of the human cdc2 promoter: release of a p130-E2F-4 complex from sequences immediately upstream of the transcription initiation site coincides with induction of cdc2 expressionIntrinsic negative cell cycle regulation provided by PIP box- and Cul4Cdt2-mediated destruction of E2f1 during S phaseAn artificial cell-cycle inhibitor isolated from a combinatorial libraryDifferent roles for cyclins D1 and E in regulation of the G1-to-S transitionNlk is a murine protein kinase related to Erk/MAP kinases and localized in the nucleusStructural basis for the recognition of the E2F transactivation domain by the retinoblastoma tumor suppressorRetinoblastoma family genesCyclin partners determine Pho85 protein kinase substrate specificity in vitro and in vivo: control of glycogen biosynthesis by Pcl8 and Pcl10.Phosphorylation of the CCAAT displacement protein (CDP)/Cux transcription factor by cyclin A-Cdk1 modulates its DNA binding activity in G(2)Control of cell cycle transcription during G1 and S phasesCooperation between the Cdk inhibitors p27(KIP1) and p57(KIP2) in the control of tissue growth and developmentSubcellular compartmentalization of E2F family members is required for maintenance of the postmitotic state in terminally differentiated muscleE2f4 is required for normal development of the airway epitheliumE2F-3B is a physiological target of cyclin ACyclin D1/Cdk4 regulates retinoblastoma protein-mediated cell cycle arrest by site-specific phosphorylationp130 and p107 use a conserved domain to inhibit cellular cyclin-dependent kinase activityIdentification of a substrate-targeting domain in cyclin E necessary for phosphorylation of the retinoblastoma proteinRetinoblastoma protein contains a C-terminal motif that targets it for phosphorylation by cyclin-cdk complexesAccumulation of human papillomavirus type 16 E7 protein bypasses G1 arrest induced by serum deprivation and by the cell cycle inhibitor p21
P2860
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P2860
Differential regulation of E2F transactivation by cyclin/cdk2 complexes
description
1994 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
1994 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 1994
@ast
im August 1994 veröffentlichter wissenschaftlicher Artikel
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scientific journal article
@en
vedecký článok (publikovaný 1994/08/01)
@sk
vědecký článek publikovaný v roce 1994
@cs
wetenschappelijk artikel (gepubliceerd op 1994/08/01)
@nl
наукова стаття, опублікована в серпні 1994
@uk
مقالة علمية (نشرت في أغسطس 1994)
@ar
name
Differential regulation of E2F transactivation by cyclin/cdk2 complexes
@ast
Differential regulation of E2F transactivation by cyclin/cdk2 complexes
@en
Differential regulation of E2F transactivation by cyclin/cdk2 complexes
@nl
type
label
Differential regulation of E2F transactivation by cyclin/cdk2 complexes
@ast
Differential regulation of E2F transactivation by cyclin/cdk2 complexes
@en
Differential regulation of E2F transactivation by cyclin/cdk2 complexes
@nl
prefLabel
Differential regulation of E2F transactivation by cyclin/cdk2 complexes
@ast
Differential regulation of E2F transactivation by cyclin/cdk2 complexes
@en
Differential regulation of E2F transactivation by cyclin/cdk2 complexes
@nl
P2093
P356
P1433
P1476
Differential regulation of E2F transactivation by cyclin/cdk2 complexes
@en
P2093
B. D. Dynlacht
J. A. Lees
P304
P356
10.1101/GAD.8.15.1772
P577
1994-08-01T00:00:00Z