Negative regulation of the growth-promoting transcription factor E2F-1 by a stably bound cyclin A-dependent protein kinase
about
E2F transcriptional activation requires TRRAP and GCN5 cofactorsE2F-7: a distinctive E2F family member with an unusual organization of DNA-binding domainsEAPP, a novel E2F binding protein that modulates E2F-dependent transcriptionImpaired DNA damage checkpoint response in MIF-deficient miceRepression of transcriptional activity of C/EBPalpha by E2F-dimerization partner complexesRegulation of TopBP1 oligomerization by Akt/PKB for cell survivalDDB, a putative DNA repair protein, can function as a transcriptional partner of E2F1.Interaction of Sp1 with the growth- and cell cycle-regulated transcription factor E2FAssociation of human CUL-1 and ubiquitin-conjugating enzyme CDC34 with the F-box protein p45(SKP2): evidence for evolutionary conservation in the subunit composition of the CDC34-SCF pathwayHuman eukaryotic translation initiation factor 4G (eIF4G) recruits mnk1 to phosphorylate eIF4ETRIP-Br: a novel family of PHD zinc finger- and bromodomain-interacting proteins that regulate the transcriptional activity of E2F-1/DP-1Reversal of growth suppression by p107 via direct phosphorylation by cyclin D1/cyclin-dependent kinase 4HIRA, the human homologue of yeast Hir1p and Hir2p, is a novel cyclin-cdk2 substrate whose expression blocks S-phase progressionNonperiodic activity of the human anaphase-promoting complex-Cdh1 ubiquitin ligase results in continuous DNA synthesis uncoupled from mitosisIdentification of a novel E2F3 product suggests a mechanism for determining specificity of repression by Rb proteinsRb and prohibitin target distinct regions of E2F1 for repression and respond to different upstream signalsFunctions of cyclin A1 in the cell cycle and its interactions with transcription factor E2F-1 and the Rb family of proteinsThe consensus motif for phosphorylation by cyclin D1-Cdk4 is different from that for phosphorylation by cyclin A/E-Cdk2Inhibition of E2F-mediated transcription by p202E2F-4 and E2F-5, two members of the E2F family, are expressed in the early phases of the cell cycleStructural basis of DNA recognition by the heterodimeric cell cycle transcription factor E2F-DPExpression of NPAT, a novel substrate of cyclin E-CDK2, promotes S-phase entryCyclin A/CDK2 binds directly to E2F-1 and inhibits the DNA-binding activity of E2F-1/DP-1 by phosphorylationAnalysis of promoter binding by the E2F and pRB families in vivo: distinct E2F proteins mediate activation and repressionDP-2, a heterodimeric partner of E2F: identification and characterization of DP-2 proteins expressed in vivoThe subcellular localization of E2F-4 is cell-cycle dependentE2F activity is regulated by cell cycle-dependent changes in subcellular localizationInduction of S-phase entry by E2F transcription factors depends on their nuclear localizationSpecific regulation of E2F family members by cyclin-dependent kinasesFunctional interaction between DP-1 and p53E2F-4 switches from p130 to p107 and pRB in response to cell cycle reentryIn vivo structure of the human cdc2 promoter: release of a p130-E2F-4 complex from sequences immediately upstream of the transcription initiation site coincides with induction of cdc2 expressionIntrinsic negative cell cycle regulation provided by PIP box- and Cul4Cdt2-mediated destruction of E2f1 during S phaseIdentification of E-box factor TFE3 as a functional partner for the E2F3 transcription factorNetwork calisthenics: control of E2F dynamics in cell cycle entryCell cycle activation of the Swi6p transcription factor is linked to nucleocytoplasmic shuttling.Active nuclear import and export pathways regulate E2F-5 subcellular localizationThe concept of synthetic lethality in the context of anticancer therapyDifferential activities of E2F family members: unique functions in regulating transcriptionControl of cell cycle transcription during G1 and S phases
P2860
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P2860
Negative regulation of the growth-promoting transcription factor E2F-1 by a stably bound cyclin A-dependent protein kinase
description
1994 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
1994 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 1994
@ast
im Juli 1994 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 1994/07/15)
@sk
vědecký článek publikovaný v roce 1994
@cs
wetenschappelijk artikel (gepubliceerd op 1994/07/15)
@nl
наукова стаття, опублікована в липні 1994
@uk
مقالة علمية (نشرت في 15-7-1994)
@ar
name
Negative regulation of the gro ...... lin A-dependent protein kinase
@ast
Negative regulation of the gro ...... lin A-dependent protein kinase
@en
Negative regulation of the gro ...... lin A-dependent protein kinase
@nl
type
label
Negative regulation of the gro ...... lin A-dependent protein kinase
@ast
Negative regulation of the gro ...... lin A-dependent protein kinase
@en
Negative regulation of the gro ...... lin A-dependent protein kinase
@nl
prefLabel
Negative regulation of the gro ...... lin A-dependent protein kinase
@ast
Negative regulation of the gro ...... lin A-dependent protein kinase
@en
Negative regulation of the gro ...... lin A-dependent protein kinase
@nl
P2093
P1433
P1476
Negative regulation of the gro ...... lin A-dependent protein kinase
@en
P2093
D. M. Livingston
M. E. Ewen
S. Shirodkar
W. G. Kaelin
P304
P356
10.1016/0092-8674(94)90582-7
P407
P577
1994-07-15T00:00:00Z