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A specific PP2A regulatory subunit, B56gamma, mediates DNA damage-induced dephosphorylation of p53 at Thr55ATM-mediated phosphorylation activates the tumor-suppressive function of B56γ-PP2AB56-containing PP2A dephosphorylate ERK and their activity is controlled by the early gene IEX-1 and ERKRegulation of XIAP translation and induction by MDM2 following irradiationProtein kinases and phosphatases in the control of cell fateCyclin G Functions as a Positive Regulator of Growth and Metabolism in DrosophilaThe genetics of the p53 pathway, apoptosis and cancer therapy.TP53/MicroRNA Interplay in Hepatocellular CarcinomaImmediate-early response 5 (IER5) interacts with protein phosphatase 2A and regulates the phosphorylation of ribosomal protein S6 kinase and heat shock factor 1p53 ubiquitination: Mdm2 and beyondNGF-mediated transcriptional targets of p53 in PC12 neuronal differentiation.Targeted disruption of the PME-1 gene causes loss of demethylated PP2A and perinatal lethality in mice.Cyclin F is degraded during G2-M by mechanisms fundamentally different from other cyclins.Germline variation in TP53 regulatory network genes associates with breast cancer survival and treatment outcome.PP2A:B56{epsilon}, a substrate of caspase-3, regulates p53-dependent and p53-independent apoptosis during development.Genetic networks lead and follow tumor development: microRNA regulation of cell cycle and apoptosis in the p53 pathways.Tumor suppressor p53 meets microRNAs.A tumor suppressor role for PP2A-B56alpha through negative regulation of c-Myc and other key oncoproteins.Suppression of p53 by Notch3 is mediated by Cyclin G1 and sustained by MDM2 and miR-221 axis in hepatocellular carcinomaRibosomal proteins RPL37, RPS15 and RPS20 regulate the Mdm2-p53-MdmX networkLysine-independent turnover of cyclin G1 can be stabilized by B'alpha subunits of protein phosphatase 2A.Abolition of cyclin-dependent kinase inhibitor p16Ink4a and p21Cip1/Waf1 functions permits Ras-induced anchorage-independent growth in telomerase-immortalized human fibroblasts.Signal transduction mediated by the Ras/Raf/MEK/ERK pathway from cytokine receptors to transcription factors: potential targeting for therapeutic intervention.miR-27b synergizes with anticancer drugs via p53 activation and CYP1B1 suppression.MDM2 regulates MYCN mRNA stabilization and translation in human neuroblastoma cellsUltraviolet-A radiation induces changes in cyclin G gene expression in mouse melanoma B16-F1 cells.Drosophila Cyclin G Is a Regulator of the Notch Signalling Pathway during Wing DevelopmentUpregulation of microRNA-122 by farnesoid X receptor suppresses the growth of hepatocellular carcinoma cells.Mdm2 in growth signaling and cancer.The Regulation of Multiple p53 Stress Responses is Mediated through MDM2Adenovirus-mediated p53 tumor suppressor gene therapy of osteosarcoma.Triptolide inhibits MDM2 and induces apoptosis in acute lymphoblastic leukemia cells through a p53-independent pathway.Protein phosphatase 1 inhibits p53 signaling by dephosphorylating and stabilizing Mdmx.The miR27b-CCNG1-P53-miR-508-5p axis regulates multidrug resistance of gastric cancer.A role for the cyclin box in the ubiquitin-mediated degradation of cyclin G1.BUBR1 recruits PP2A via the B56 family of targeting subunits to promote chromosome congression.PR55α Subunit of Protein Phosphatase 2A Supports the Tumorigenic and Metastatic Potential of Pancreatic Cancer Cells by Sustaining Hyperactive Oncogenic Signaling.Hepatitis B virus X protein mediated suppression of miRNA-122 expression enhances hepatoblastoma cell proliferation through cyclin G1-p53 axisMicroRNA involvement in hepatocellular carcinoma.Comprehensive phenotypic analysis of knockout mice deficient in cyclin G1 and cyclin G2.
P2860
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P2860
description
2002 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2002
@ast
im April 2002 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2002/04/01)
@sk
vědecký článek publikovaný v roce 2002
@cs
wetenschappelijk artikel (gepubliceerd op 2002/04/01)
@nl
наукова стаття, опублікована у квітні 2002
@uk
مقالة علمية (نشرت في أبريل 2002)
@ar
name
Cyclin G recruits PP2A to dephosphorylate Mdm2
@ast
Cyclin G recruits PP2A to dephosphorylate Mdm2
@en
Cyclin G recruits PP2A to dephosphorylate Mdm2
@nl
type
label
Cyclin G recruits PP2A to dephosphorylate Mdm2
@ast
Cyclin G recruits PP2A to dephosphorylate Mdm2
@en
Cyclin G recruits PP2A to dephosphorylate Mdm2
@nl
prefLabel
Cyclin G recruits PP2A to dephosphorylate Mdm2
@ast
Cyclin G recruits PP2A to dephosphorylate Mdm2
@en
Cyclin G recruits PP2A to dephosphorylate Mdm2
@nl
P2093
P3181
P1433
P1476
Cyclin G recruits PP2A to dephosphorylate Mdm2
@en
P2093
Carol Prives
Hongyun Li
Koji Okamoto
Michael R. Jensen
Snorri S. Thorgeirsson
Tingting Zhang
Yoichi Taya
P304
P3181
P356
10.1016/S1097-2765(02)00504-X
P577
2002-04-01T00:00:00Z