MDM2 regulates MYCN mRNA stabilization and translation in human neuroblastoma cells
about
Neuroblastoma: oncogenic mechanisms and therapeutic exploitation of necroptosisNoscapine induced apoptosis via downregulation of survivin in human neuroblastoma cells having wild type or null p53A cell-based high-throughput screen addressing 3'UTR-dependent regulation of the MYCN gene.Stress-induced alternative splice forms of MDM2 and MDMX modulate the p53-pathway in distinct waysInhibition of MDM2 homodimerization by XIAP IRES stabilizes MDM2, influencing cancer cell survival.Mdm2 promotes myogenesis through the ubiquitination and degradation of CCAAT/enhancer-binding protein β.Crosstalk between MYCN and MDM2-p53 signal pathways regulates tumor cell growth and apoptosis in neuroblastomaTargeting MYCN IRES in MYCN-amplified neuroblastoma with miR-375 inhibits tumor growth and sensitizes tumor cells to radiationDiscovery of Dual Inhibitors of MDM2 and XIAP for Cancer Treatment.Cell survival signaling in neuroblastoma.Neuroblastoma and MYCNPolysome Preparation, RNA Isolation and Analysis.The Gpr1/Zdbf2 locus provides new paradigms for transient and dynamic genomic imprinting in mammals.Mdm2 and MdmX as Regulators of Gene ExpressionMDM2's social network.MDM2 but not MDM4 promotes retinoblastoma cell proliferation through p53-independent regulation of MYCN translation.p53, SKP2, and DKK3 as MYCN Target Genes and Their Potential Therapeutic Significance.A novel mouse model of rhabdomyosarcoma underscores the dichotomy of MDM2-ALT1 function in vivo.Cell death-based treatment of neuroblastoma.
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MDM2 regulates MYCN mRNA stabilization and translation in human neuroblastoma cells
description
2011 nî lūn-bûn
@nan
2011 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2011年の論文
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2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
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name
MDM2 regulates MYCN mRNA stabilization and translation in human neuroblastoma cells
@ast
MDM2 regulates MYCN mRNA stabilization and translation in human neuroblastoma cells
@en
type
label
MDM2 regulates MYCN mRNA stabilization and translation in human neuroblastoma cells
@ast
MDM2 regulates MYCN mRNA stabilization and translation in human neuroblastoma cells
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prefLabel
MDM2 regulates MYCN mRNA stabilization and translation in human neuroblastoma cells
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MDM2 regulates MYCN mRNA stabilization and translation in human neuroblastoma cells
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MDM2 regulates MYCN mRNA stabilization and translation in human neuroblastoma cells
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10.1038/ONC.2011.343
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2011-08-08T00:00:00Z
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1033494223